Award Data

Project Summary/AbstractFunding Opportunity Number: USDA-NIFA-SBIR-009301Topic Area 8.8: Biofuels and Biobased ProductsTitle of Project: Designer Biochar - Low-cost adsorbents and fertilizers for nitrate and phosphateadsorption and nutrient deliveryPD/PI: Brigano Frank A. Glanris Inc.Co PD/PI: Mlsna Todd E. Mississippi State UniversityCo PD/PI: Pittman Charles Mississippi State UniversityGlanris I ...

The use of high throughput genetic data has transformed animal agriculture dramatically overthe last 17 years.Large breed associations and national breeding programs are collecting genomewide genotypes and implementing genomic selection to improve production phenotypes.Thesetechnologies have proven both powerful and transformative.They have also become inexpensive.Whole genome genotypes can be gen ...

ABSTRACT Approximately 700,000 people in the United States are diagnosed with a primary brain tumor. Of these, malignant gliomas (MGs) account for approximately 40% of all intracranial tumors, with an overall survival rate of only ~34%. Surgical resection remains the cornerstone of therapy and the extent of resection correlates with survival. Fluorescence imaging has emerged as an adjunctive techn ...

ABSTRACT Continuous monitoring of neonatal brain development is crucial for effective management of brain injury and associated complications, thus reducing healthcare burden and costs. One rapidly developing method for early characterization of abnormal brain development is to map resting-state functional connectivity (rs-FC) across distinct regions of the brain. However, currently available neur ...

Project Summary I-RED Southeast XLerator Network, powered by XLerateHealth, LLC in collaboration with the University of Kentucky as the lead academic partner institution, proposes to develop a suite of experience-based entrepreneurship education products and commercialization education tools to address the needs of academic institutions and their faculty, researchers, innovators, and graduate/unde ...

Modern pharmaceuticals have greatly improved the quality of life for many patients suffering a variety of illnesses. Unfortunately, among the 17 most commonly prescribed drugs, only 6 are highly effective for most patients, 5 have a modest effect, and 6 show little clinical effect. Worse still, unwanted illness and death from treatment of patients with the incorrect drug or dosage causes over 275, ...

Project Summary/Abstract: Due to decreased mobility, deterioration in activities of daily living, and neurological decline that contributes to loss of bladder control, incontinence is a leading comorbidity for those individuals suffering from Alzheimer’s disease and related dementias (ADRD). Further, individuals with incontinence are susceptible to the development of pressure ulcers (PUs), with ...

ABSTRACT The identification and removal of process-related protein impurities (PRPI) from biologic products is a critical step in drug development. Despite recent improvements in the purification and processing of biologics, the presence of immunogenic PRPI continue to raise concerns about drug safety and efficacy. We propose an innovative approach for assessing immunogenicity risk of PRPI using o ...

Project Summary Model cells for cancer research and drug discovery are currently stored using cryogenic methods that necessitate powerful freezers and liquid nitrogen. Frozen cells require regular upkeep, have high energy costs, take up a lot of space, and rapidly degrade if cooling devices fail. Efforts to develop a lyophilization protocol for model cell lines have been ongoing for decades, howev ...

Project Summary This proposal develops key aspects of an ultrasensitive pathogen detection system for rodent animal health surveillance and is in response to the NIH FOA PAR-21-225 to develop novel tools and devices for animal research facilities and to support the care of animal models. The goal of the project is to develop a microfluidic device for rapid and inexpensive pathogen detection direct ...