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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. N/A

    SBC: ABACUS HEALTH SOLUTIONS, LLC            Topic: N/A

    N/A

    STTR Phase I 2000 Department of Health and Human ServicesNational Institutes of Health
  2. Inhibition of methanogenesis

    SBC: BIONEBRASKA, INC.            Topic: N/A

    DESCRIPTION:(provided by applicant) The goal of this project is to develop a novel inhibitor of methane formation in ruminant animals. Currently, monensin, a relatively nonspecific antibiotic, is widely used in the livestock industry. Monensin increases agricultural productivity by decreasing methane and increasing propionate production; however, it also inhibits ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  3. Transmucosal Intra-Oral Drug Delivery System for THC

    SBC: ElSohly Laboratories, Incorporated            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this research project is to develop an effective, hot-melt extruded "Transmucosal Matrix Patch" (TMP) as a delivery system for Delta-9-Tetrahydrocannabinol (THC). THC will be incorporated into a stable, bioadhesive drug delivery system that is applied to a subject's buccal or labial oral mucosa. The controlled release of THC is delivered to ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  4. Compositions for Prevention/Prophylactic Treatment of Poison Ivy Dermatitis

    SBC: ElSohly Laboratories, Incorporated            Topic: N/A

    DESCRIPTION (provided by applicant): The long term objectives of this proposal are aimed at the development of new composition(s) to be used for the prophylactic treatment/prevention of poison ivy contact dermatitis in sensitive individuals. Poison ivy/poison oak and another related species poison sumac are the main cause of occupational hazards for outdoor workers in the United States. Most of th ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Transmucosal Intra-Oral Drug Delivery System for THC

    SBC: ElSohly Laboratories, Incorporated            Topic: N/A

    DESCRIPTION (provided by applicant): Delta-9-Tetrahydrocannabinol (THC), the active ingredient in the cannabis plant, has a wide range of pharmacological properties of therapeutic value. The drug has been approved by the Food and Drug Administration (FDA) (Marinol(r) soft gelatin capsules) for the treatment of nausea and vomiting associated with chemotherapy and for appetite stimulation in AIDS p ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  6. Compositions for Prevention/Prophylactic Treatment of Poison Ivy Dermatitis

    SBC: ElSohly Laboratories, Incorporated            Topic: N/A

    DESCRIPTION (provided by applicant): Poison ivy/oak contact dermatitis is the most prevalent skin allergy in the United States, affecting gt50% of the adult population. The condition is the major cause of occupational hazard among outdoor workers in forestry, agriculture and firefighting, resulting in significant medical expenses and workers disability. Attempts have been made to provide prophyla ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  7. Generation of Human Hepatocytes

    SBC: IN VIVO TECHNOLOGIES            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to produce "humanized" livers in large animal models such as sheep and pigs that can serve as a reliable source of significant numbers of functional human hepatocytes. The isolated human hepatocytes and/or "humanized" livers can be used for drug toxicity studies as well as for possible clinical use in patients with liver failure. Tra ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  8. Electro-Mechanical Micro-Post Array to Detect In Vitro Muscle Contraction

    SBC: MYOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Myomics? technology to be developed in this Phase 1 project is based upon an in vitro skeletal muscle tissue force measurement technique for high throughput screening (HTS) of compounds to attenuate muscle weakness. The technology, termed Patterned Micro-Post-Arrays (P-fPA), is comprised of bioengineered skeletal muscle tissue attached to micro-mechanical senso ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  9. A Peptide-Based Vaccine to Nicotine

    SBC: Prommune, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The primary objective of this Phase I STTR project is to develop an effective, peptide-based nicotine vaccine for use in humans capable of inducing a robust, nicotine-specific antibody (Ab) response with little or no inflammatory side effects. This will be accomplished by a vaccine design in which a conformationally biased, response-selective agonist Of C5a ( ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. Role of Inter-alpha Inhibitors in Anthrax Intoxication

    SBC: PROTHERA BIOLOGICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The primary goal of this proposal is to demonstrate the feasibility of utilizing Inter-alpha Inhibitor proteins (lalp) as an effective protective agent against exposure to anthrax, a lethal biological warfare agent. Inter-alpha inhibitor proteins are natural serine protease inhibitors found in relatively high concentration in human plasma. The protein complex h ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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