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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Topic 377: Symptom Management and Intervention Roadmaps (STaIRS)

    SBC: Carevive Systems, Inc.            Topic: NCI

    Numerous adverse symptoms are under-detected in cancer care resulting1-3 in missed opportunities for intervention; leading to poor treatment adherence, avoidable hospitalizations, and worse morbidity and survival. The IOM proposed shaking up the current symptom paradigm from reactive to proactive, personalized, technology-enabled models of symptom care as a solution to this clinical quality crisis ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. A novel biomaterial based therapy utilizing auto antigen and adjuvant for the amelioration of Type Diabetes

    SBC: ONEVAX, LLC            Topic: NIAID

    Immune mediated diseases such as type diabetes T D multiple sclerosis rheumatoid arthritis and systemic lupus erythematosis are reaching epidemic proportions in the US T D affects an estimated million Americans with more than new patients diagnosed annually resulting in roughly $ B in health care costs in the US each year T D is an autoimmune disease characterized by effector ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. An interactive App to Promote Safe and Effective use of Opioids in Young Children Postoperatively

    SBC: ARCHIE MD INC.            Topic: NIDA

    In recent years increased attention to pain in children and adolescents has led to a recent fold increase in opioid prescriptions Unsurprisingly the annual rates of analgesic related adverse drug events AR ADEs have soared to include andgt hospital admissions and hundreds of accidental overdose deaths in children and adolescents and has remained a significant problem At the heart of ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Biomaterial based delivery of Interleukin to Regulatory T Cells for the amelioration of Type Diabetes

    SBC: ONEVAX, LLC            Topic: NIAID

    Type Diabetes T D results from a breakdown of self tolerance that is characterized by immune cell mediated destruction of the insulin producing cells in the pancreas Ultimately glucose metabolism is interrupted resulting in the development of life threatening complications such as heart disease and renal failure T D affects an estimated million Americans with more than new patie ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. A Preclinical Trial of Therapeutic Angiogenesis Plus Angioplasty and Stenting for Renal Vascular Disease

    SBC: Leflore Technologies LLC            Topic: 400

    Abstract Chronic kidney disease CKD is a progressive disorder affecting almost of the general population and this disease has shown a relentless growth over the past decades Patients with CKD have higher rates of hospitalization greater mortality shorter life expectancy and their healthcare costs are up to times more expensive than non CKD patients Thus treatments to slow halt ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Insert Earphones with Integrated In Ear Calibration

    SBC: Intelligent Hearing Systems Corp.            Topic: Y

    The specific aim of this project is to develop an insert earphone with integrated in ear sound level calibration capabilities Insert earphones provide great advantages for hearing testing with a convenient and comfortable way to deliver a stimulus with high noise and intra aural attenuation They not surprisingly have become a standard clinical transducer However their exact calibration over a ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Innovation for the earlydetection diagnosis and quantification of diabetic cardiomyopathy

    SBC: AVENTUSOFT L.L.C.            Topic: 200

    PROJECT SUMMARY ABSTRACT This SBIR Phase I project will develop an innovative medical device useful for rapid automated characterization of myocardial performance in diabetes patients Left ventricular systolic and diastolic myocardial impairment is the most common manifestation and the systolic function is monitored with left ventricular ejection fraction measurement and the diastolic function i ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. A computational platform to prioritize drugs and target genes for therapeutic intervention

    SBC: Genetic Networks, LLC            Topic: NCATS

    Project Summary This project proposes implementation of a computational discovery platform that quantifiably identifies and prioritizes both targets and compounds for therapeutic intervention This platform is based on a novel fusion of two state of the art computational approaches phenolog mapping and functional networks with proprietary data from our powerful gene drug screening assays HIP H ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Low Cost Catalytic Biomass Cookstove for Improved Indoor Air Quality

    SBC: MAINSTREAM ENGINEERING CORPORATION            Topic: NIEHS

    Project Summary An estimated billion people or about one third of the world s population rely on biomass fuel for cooking Emissions from biomass cookstoves contribute to global climate change indoor local air quality issues and related health effects In particular indoor air quality issues related to biomass cookstoves contribute significantly to rates of acute respiratory infection Re ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Therapeutic Administration of Suppressor of Cytokine Signaling Mimetics to Ameliorate Type Diabetes

    SBC: ONEVAX, LLC            Topic: NIAID

    Type Diabetes T D results from a breakdown of self tolerance that is characterized by immune cell mediated destruction of the insulin producing cells in the pancreas Ultimately glucose metabolism is interrupted resulting in the development of life threatening complications such as heart disease and renal failure T D affects an estimated million Americans with more than new patie ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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