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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Multi Source E Beam kV X Ray Tube for Image Guided Radiotheraphy

    SBC: TELESECURITY SCIENCES, INC.            Topic: 102

    DESCRIPTION provided by applicant This project will develop a commercial product that will enable for the first time realtime tumor tracking during radiotherapy at an attractive price point and with minimal interference with standard clinical practice The key novel technology is an optimized multi source X ray tube with focal spots that is placed below the multi leaf collimator MLC of a r ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. I Live Inspired Individually Tailored and Integrated Social Support Network for Tobacco Cessation

    SBC: Live Inspired, LLC            Topic: NIDA

    DESCRIPTION provided by applicant Smoking kills Americans annually exacerbates myriad diseases and costs billions in healthcare and productivity losses Numerous barriers exist to accessing traditional treatment e g costs traveling to and scheduling appointments other logistics Text messaging is an extremely popular communication method Over of all Americans use text m ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Point of care immunoassay for rapid diagnosis of tinea capitis

    SBC: DxDiscovery Incorporated            Topic: NIBIB

    Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. In Situ Autovaccination against Solid Cancers with Intratumoral Hiltonol Poly ICLC A phase II Adaptive Multicenter Clinical Study

    SBC: Oncovir            Topic: 102

    DESCRIPTION provided by applicant Hiltonol poly ICLC is a stabilized dsRNA therapeutic viral mimic or andapos danger signalandapos that activates multiple elements of innate and adaptive immunity It is a standalone immunomodulator but when properly combined with antigen it generates a comprehensive Th weighted immune response best suited for antiviral and antitumor action This project ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Accurate Nightlight for Satellite Calibration for Weather and Climate Applications

    SBC: INNOVATIVE IMAGING & RESEARCH CORP            Topic: 843

    This project’s aim is to develop an Accurate Active Light Source (AALS) that can be fielded at selected calibration sites to address NOAA’s unmet needs and improve the calibration of the Suomi NPP VIIRS Day Night Band (DNB) operating in the high gain stage (HGS) under low light level conditions. The DNB HGS has extreme low-light sensitivity that enables a new generation of nighttime imaging. M ...

    SBIR Phase II 2016 Department of Commerce
  8. Probabilistic subseasonal weather forecasts for the energy & agriculture sectors

    SBC: CLIMATE FORECAST APPLICATIONS NETWORK, LLC            Topic: 831

    This proposal from Climate Forecast Applications Network addresses the challenge of providing business-relevant subseasonal forecasts for the energy and agricultural sectors, including applications to renewable energy. An innovative multi-model prediction system using the CFSv2 and ECMWF forecasts will be developed to exploit the advantages of each model. An interactive web-based dashboard system ...

    SBIR Phase II 2016 Department of Commerce
  9. High Stability Atmospheric Carbon Dioxide and Methane Analyzer

    SBC: LI-COR, Inc.            Topic: 832

    LI-COR proposes to develop a next-generation CO2/CH4/H2O analyzer that will offer an unprecedented combination of high precision and stability, making it the first high-performance gas analyzer suitable for long-term unattended operation. The instrument will be smaller, lighter, and far less expensive than competing technologies. LI-COR’s approach exploits a proprietary, revolutionary design tha ...

    SBIR Phase I 2016 Department of Commerce
  10. Smart Module Commercial Development Research

    SBC: Mechelen, LLC            Topic: 852

    Most sensor data collection systems are unique to a given application, sensors do not easily transcend across applications or platforms. Smart sensor development improved the ability to utilize common communications to a certain degree, where most used RS-232 or RS-485 type communications protocols, but differences are still found and no uniformity exists in the commercial markets. The Smart Modul ...

    SBIR Phase I 2016 Department of Commerce

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