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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Universal Attenuated Sporozoite Vaccine and Challenge System

    SBC: SANARIA INC.            Topic: NIAID

    ABSTRACT Sanaria s Plasmodium falciparumPfsporozoiteSPZvaccines development program is receiving global supportTrials of PfSPZ Vaccineradiation attenuated PfSPZor PfSPZ CVacPfSPZ Chemoprophylaxis Vaccineadministered by direct venous inoculationDVIincludingadults to infants were initiated in DecemberTanzaniaU Sor will be initiated in earlyin MaliKenyainfantsGhanaEquatorial GuineaGermany andaddition ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Advancing a Glioma Immunotherapy

    SBC: IN CYTU, INC.            Topic: 102

    DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. A Holistic Approach to Optimal and Secure Tactical Wireless Broadband Systems

    SBC: INTELLIGENT FUSION TECHNOLOGY, INC.            Topic: AF112055

    ABSTRACT:In the Phase I effort, IFT proposed a Holistic networking Infrastructure for tactical Satellite Communication Networks (HISCoN). It supports optimal network resource management and cross-layer cooperation that allow satellite communication networks to intelligently accommodate the communication needs of various missions/tasks with diverse traffic characteristics and drastically different ...

    SBIR Phase II 2016 Department of DefenseAir Force
  4. Protease chain reactions for molecular analysis of cancer markers

    SBC: POTOMAC AFFINITY PROTEIN LLC            Topic: 102

    DESCRIPTION provided by applicant Our objective is to develop a Protease Chain Reaction technology ProCR that will enable ultra sensitive and highly quantitative detection of cancer markers The basic element of a protease chain reaction is a protease inhibitor complex The protease is inactive when bound to the inhibitor but once freed is capable of cleaving the inhibitor and releasing ad ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Software for improved accuracy and rapid tracking of kinematics from dynamic Xray

    SBC: C-MOTION, INC.            Topic: NIAMS

    DESCRIPTION provided by applicant Orthopaedic disorders are a leading cause of disability in the U S with arthritis and or spine problems adversely affecting quality of life fo more than of adults While advances in diagnostic imaging have greatly improved our ability to detect structural changes in musculoskeletal tissues they typically reveal little about joint function There is evid ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Heimdall MSSS Strategic Collection

    SBC: ORBIT LOGIC INCORPORATED            Topic: AF141015

    ABSTRACT: Orbit Logic and the University of Colorado propose the Heimdall System to schedule observations of known objects and search for and establish custody of unknown objects from the Maui Space Surveillance Site. The Heimdall System includes a modeling environment a scheduling engine, and a track prioritization component. Within the Heimdall System, Finite Set Statistics (FISST) methods will ...

    SBIR Phase II 2016 Department of DefenseAir Force
  7. Versatile Live Patching System (VLPS)

    SBC: Intelligent Automation, Inc.            Topic: AF141044

    ABSTRACT: Patch management is one of the main enabling technologies in maintaining a high degree of security for IT systems.Often the patch requires a higher level of privilege to apply, making the patching operation itself a potential target of exploitation.The update or patch might require a reboot or perceivable system downtime, which becomes an issue for level 1 or 2 mission assurance category ...

    SBIR Phase II 2016 Department of DefenseAir Force
  8. Global Surveillance Augmentation Using Commercial Satellite Imaging Systems

    SBC: VISION SYSTEMS INC            Topic: AF153001

    ABSTRACT:A system is proposed to access, collate and process imagery from multiple small satellite constellations. The imagery is fused and registered to a common reference so that exploitation algorithms, such as change detection and event monitoring, are reported with accurate geographic coordinates. The system, called SatTel, is implemented as open source software that is designed to run on the ...

    SBIR Phase II 2016 Department of DefenseAir Force
  9. Computerizing NIAAA's Best Practices for Youth Screening and Brief Intervention

    SBC: COG ANALYTICS, LLC            Topic: 400

    DESCRIPTION provided by applicant The early onset of alcohol misuse during adolescence is a widespread problem in the U S Studies have consistently documented both the short and long term adverse neurophysiological impacts and health risk behaviors associated with alcohol misuse during adolescence Given the magnitude of this problem and its myriad consequences preventing early initiation of ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Effectiveness of VBP15, a dissociative steroidal analogue, on chronic inflammation in a mouse model of multiple sclerosis

    SBC: REVERAGEN BIOPHARMA, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Glucocorticoids GCandapos s such as prednisolone are used frequently to induce remission and treat multiple sclerosis MS Despite effectiveness many GC mediated detrimental side effects including osteoporosis and muscle atrophy limit long term chronic treatment of MS patients These side effects are believed to be mediated by well described glucocorticoi ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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