Award Data

DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...

ABSTRACT: Many turbomachinery applications have achieved improved availability, reliability and cost savings by incorporating health monitoring systems to determine the mechanical condition of key components in near real time. The goals of any health monitoring system are to ensure reliability by avoiding unplanned maintenance, to reduce operating costs by providing the information needed to plan ...

ABSTRACT: The Air Force spends $4.5 billion annually on aircraft maintenance related to corrosion.The source of this corrosion frequently is airborne chlorides that settle on metal parts and sensitive avionics and then absorb moisture from the air to create an electrolyte that promotes galvanic corrosion.The proposed work will design, fabricate and test a Corrosion Mitigation System (CMS) that sup ...

ABSTRACT: The objective of the effort is the development of a Femtosecond Laser Electronic Excitation Tagging (FLEET) system and data analysis tools for the measurement of transport parameters in nitrogen and air ground test facilities without seeding the flow with either particles or with foreign gases.  The effort follows Phase I accomplishments, wherein a transportable FLEET laser system with ...

ABSTRACT:A system is proposed to access, collate and process imagery from multiple small satellite constellations. The imagery is fused and registered to a common reference so that exploitation algorithms, such as change detection and event monitoring, are reported with accurate geographic coordinates. The system, called SatTel, is implemented as open source software that is designed to run on the ...

DESCRIPTION provided by applicant Therapeutics based on nucleic acids NA promise to revolutionize treatment of multiple diseases but their widespread use is currently limited by the lack of efficient delivery methods We have recently developed a new NA delivery platform based on polymeric CXCR inhibitors PCX suitable as dual function systems for simultaneous NA delivery and inhibition of ...

DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

DESCRIPTION provided by applicant A number of academic groups and life sciences companies are developing and testing approaches to delay aging the most significant risk factor for the vast majority of serious human diseases Critical for these efforts is the development and validation of minimally invasive cost effective biomarkers of aging DiamiR a molecular diagnostics company has deve ...

DESCRIPTION provided by applicant Urinary incontinence UI and overactive bladder OAB are highly prevalent in women and their prevalence is increased with the age In a representative United States survey UI was reported to affect from to of women The OAB prevalence estimates vary considerably among studies ranging from to These conditions are socially embarrassing causin ...

DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...