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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. In Situ Autovaccination against Solid Cancers with Intratumoral Hiltonol Poly ICLC A phase II Adaptive Multicenter Clinical Study

    SBC: Oncovir            Topic: 102

    DESCRIPTION provided by applicant Hiltonol poly ICLC is a stabilized dsRNA therapeutic viral mimic or andapos danger signalandapos that activates multiple elements of innate and adaptive immunity It is a standalone immunomodulator but when properly combined with antigen it generates a comprehensive Th weighted immune response best suited for antiviral and antitumor action This project ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Point-of-care immunoassay for early diagnosis of pertussis

    SBC: DXDISCOVERY INC            Topic: R

    Project Summary Pertussis is rapidly re emerging as a serious public health threat in the United StatesDespite high vaccine coverage nationallyannual reported cases in the U Shave been increasing recentlywith ayear high ofinMoreoverreported cases represent a large underestimate of pertussis infectionsDiagnosis of early pertussiscatarrhal stageprior to paroxysmal coughis particularly challenging be ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. I Live Inspired Individually Tailored and Integrated Social Support Network for Tobacco Cessation

    SBC: LIVE INSPIRED LLC            Topic: NIDA

    DESCRIPTION provided by applicant Smoking kills Americans annually exacerbates myriad diseases and costs billions in healthcare and productivity losses Numerous barriers exist to accessing traditional treatment e g costs traveling to and scheduling appointments other logistics Text messaging is an extremely popular communication method Over of all Americans use text m ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Multi Source E Beam kV X Ray Tube for Image Guided Radiotheraphy

    SBC: Telesecurity Sciences, Inc.            Topic: 102

    DESCRIPTION provided by applicant This project will develop a commercial product that will enable for the first time realtime tumor tracking during radiotherapy at an attractive price point and with minimal interference with standard clinical practice The key novel technology is an optimized multi source X ray tube with focal spots that is placed below the multi leaf collimator MLC of a r ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. AcetaSTAT Rapid Assay for Acetaminophen Liver Injury

    SBC: ACETAMINOPHEN TOXICITY DIAGNOSTICS, LLC            Topic: 300

    DESCRIPTIONprovided by applicantAlthough acetaminophen is the most common drug for treating pain and feverand also the most common cause of life threatening drug induced liver damagethere are no tests that specifically diagnose a liver injury from an overdoseThe object of this grant is to complete the development of AcetaSTAT ran innovative new method to diagnose an acetaminophen overdoseThe new t ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Advancing a Glioma Immunotherapy

    SBC: IN CYTU, INC.            Topic: 102

    DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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