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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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TARGETING STEALTH LIPOSOME FOR CANCER GENE THERAPY
SBC: SYNERGENE THERAPEUTICS, INC. Topic: N/AAdvanced prostate cancer tends to be relatively refractory to standard chemotherapeutic agents, and this chemoresistance correlates with a lack of functional p53. Our preliminary data indicate that cancer cells can be sensitize to chemotherapy via p53 replacement using a tumor-targeting liposomal delivery system. The low stability and rapid clearance from circulation of these ligand-liposomes are ...
STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health -
IMMUNOLIPOSOME-MEDIATED GENE THERAPY FOR PROSTATE CANCER
SBC: SYNERGENE THERAPEUTICS, INC. Topic: N/ADESCRIPTION (provided by applicant): Advanced prostate cancer tends to be relatively refractory to standard chemotherapeutic agents and radiation treatment, and this resistance correlates with a lack of functional p53. Our previous data indicate that cancer cells can be sensitized to radiation and chemotherapy via p53 replacement using a tumor-targeting liposomal delivery system. In the STTR Phase ...
STTR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health -
IMMUNOLIPOSOME-MEDIATED GENE THERAPY FOR PROSTATE CANCER
SBC: SYNERGENE THERAPEUTICS, INC. Topic: N/ADESCRIPTION (provided by applicant): Advanced prostate cancer tends to be relatively refractory to standard chemotherapeutic agents and radiation treatment, and this resistance correlates with a lack of functional p53. Our previous data indicate that cancer cells can be sensitized to radiation and chemotherapy via p53 replacement using a tumor-targeting liposomal delivery system. In the STTR Phase ...
STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health -
Development of nucleic acid delivery platform based on polymeric CXCR4 antagonists
SBC: Bohemica Pharmaceuticals, LLC Topic: 100DESCRIPTION provided by applicant Therapeutics based on nucleic acids NA promise to revolutionize treatment of multiple diseases but their widespread use is currently limited by the lack of efficient delivery methods We have recently developed a new NA delivery platform based on polymeric CXCR inhibitors PCX suitable as dual function systems for simultaneous NA delivery and inhibition of ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Mutation Enriched Targeted Re Sequencing
SBC: TRANSGENOMIC, INC. Topic: 103DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Precision, pulmonary disease evaluation and lung cancer detection using quantitative low-dose CT
SBC: VIDA DIAGNOSTICS, INC. Topic: 102DESCRIPTION provided by applicant Lung cancer is responsible for more cancer deaths than breast prostate and colon cancers combined Minimal improvements in the five year survival rate for lung cancer have occurred over the past thirty years Recently a mortality benefit has been demonstrated for lung cancer screening using low dose computed tomography LDCT in people with high cancer risk ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
An Automated Patient Chart Error Detection System for Radiation Therapy
SBC: Infondrian LLC Topic: 101Project Summary Abstract Every year approximately severe mistreatments happen in radiation therapy Radiation therapy lawsuits rank in the top third of all medical specialties with an average of $ per claim settled or litigated The current method for detecting treatment errors is by a weekly patient chart check where each treatment record is manually reviewed on a weekly basis Thi ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Ultrasensitive SERS Nano-Sensors for Pancreatic Cancer Diagnosis and Prognosis
SBC: Sanguine Diagnostics And Therapeutics, Inc. Topic: 103ABSTRACT Pancreatic cancer PC is an extremely aggressive malignancy with one of the worst prognoses of all cancers with a median survival of less than one year and an overall year survival of andlt With marked resistance to chemo and radiotherapies surgery is the only curative option In patients with localized disease and no lymph node or extra pancreatic metastases complete surgical ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Development of Chol-DsiRNA Polyplexes to Improve the Therapy of Breast Cancer
SBC: ACTORIUS PHARMACEUTICALS, LLC Topic: 100DESCRIPTION provided by applicant Breast cancer is the most common type of cancer in women between the ages of and and responsible for deaths annually If treated early five year survival rates for patients in the U S are between and but drop to once metastatic breast cancer has developed Thus there is a great need to develop more effective treatment strategies fo ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
A brief iPad based screening measure for HIV associated neurocognitive disorders
SBC: Digital Artefacts LLC Topic: 105Despite significance advances in anti retroviral treatments HIV associated neurocognitive disorder HAND remains prevalent and can affect a broad range of everyday activities An effective brief cognitive screen that could be implemented in busy HIV clinics where clinicians have limited time to provide care for patients with complex medical psychiatric and cognitive conditions has the poten ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health