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Award Data
The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A novel glutaminase-free mammalian asparaginase with minimized immunogenicity to enable expanded use in cancer therapy
SBC: Enzyme by Design Inc. Topic: 102PROJECT SUMMARY Enzyme by DesignIncEbDis developing a safer version of L asparaginase that can be used routinely in the treatment of adult ALL patients whose hypersensitivity to todayandapos s bacterial L asparaginases deprives them from this efficacious therapyEbDandapos s L asparaginase is novel due to its mammalianguinea pigorigin and its lack of L glutaminase co activityThe need for better the ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Optimization of Novel Ryanodine Receptor Modulatory Compounds for Alzheimer's Disease
SBC: NeuroLucent Topic: NIAAbstract Summary Currentlythere are no effective treatments to preserve cognitive function in AD patients and the recent series of disappointing clinical trials highlight the need to explore alternative pathwaysTo this endNeuroLucent Incand its academic partnerRFUMSare developing small molecule compounds designed as allosteric modulators of the ryanodine receptorRyRa high conductance calcium chann ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Immersive Virtual Reality as a Tool to Improve Police Safety in Adolescents and Adults with ASD
SBC: Floreo, Inc. Topic: 103Floreo Technology proposes to develop the Police Safety Module (PSM), an innovative, immersive mobile virtual reality (VR) application designed to train police safety in adolescents and adults with autism spectrum disorder (ASD). ASD has been increasing in prevalence over recent years. While much attention has been paid to the causes and early diagnosis of ASD, there remains a clear need for effec ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Robot-Assisted Cognitive Training for Socially Isolated Older Adults with Mild Cognitive Impairment
SBC: Applied Universal Dynamics, Corp. Topic: NIAProject Summary Abstract This project will develop a Socially Assistive RobotSARto provide cognitive trainingin the form of learning to play the pianoto improve cognitive functioning and reduce feelings of loneliness in socially isolated older adultsThe SAR will administer cognitive training via guided practice on a set of standard piano lesson tasks designed to reflect particular cognitive functi ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
C.A.R.E.S.: A Mobile Health Program for Alcohol Risk Reduction for an Under-Served College Population
SBC: LIVE INSPIRED LLC Topic: 550Project Summary AbstractExcessive alcohol use is the third leading preventable cause of death in the U Swith young adults agesshowing the highest rates of hazardous alcohol useCommunity colleges serve overmillion studentscomprisingof all U Scollege studentsCommunity college studentsCCSshow rates of heavy alcohol use similar to students at traditional four year residentialFYRcollegesbut CCS are at ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Validation of a Novel Fungicidal Approach for Cryptococcal Meningitis
SBC: Minnetronix Medical, Inc. Topic: NIAIDABSTRACT When Cryptococcus is manifested as cryptococcal meningitis (CM), it creates a large burden of mortality and morbidity to the patient and is very difficult for the clinician to treat. There are now an estimated 2600-7800 US cases and 400,000 cases of CM worldwide annually, with estimated mortality of 15-50% per year. CM is caused when Cryptococcus neoformans, a basidiomycete fungal pathoge ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
An Opioid/Cannabinoid Analgesic that Boosts Pain Relief and Blocks Opiate Reward
SBC: ElSohly Laboratories, Incorporated Topic: NIDAProject Summary Abuse of prescription opioids and fatalities related to their misuse have increased sharply in recent yearsmaking the development of pain medications with reduced abuse potential a major public health priorityWhen combinedopioids and cannabinoidCBreceptor agonists show analgesic effects appear to be at least additive in a number of pain modelsCannabidiolCBDalthough much less psycho ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Validation of Novel Therapeutic Approach for Leptomeningeal Metastases
SBC: Minnetronix Medical, Inc. Topic: 102ABSTRACT Leptomeningeal Metastases (LM) is a condition in which tumor cells from a primary tumor metastasize, invade the subarachnoid space (SAS) and spread throughout the cerebrospinal fluid (CSF), resulting in seeding along the meninges, brain and spinal cord. LM represents a devastating event of cancer progression. There are 30,000 cases annually and currently no cure, with average survival of ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of mitochondrial disease mouse models
SBC: B-MoGen Biotechnologies Inc Topic: ODProject Abstract Mitochondria are double membrane bound organelles that are found in all eukaryotic cells and carry a specialized circularkb genomeThere is a group of devastating human genetic diseases caused by inherited or spontaneous mutation of genes encoded within the mitochondrial genomeThese diseases can cause a wide array of medical problems from subtle muscular weakness to extreme neuromu ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Mobile Support to Improve Recovery and Treatment Court Outcomes
SBC: LIVE INSPIRED LLC Topic: NIDAPROJECT SUMMARY ABSTRACTDrug Treatment CourtsDTCsare a rapidly evolving alternative to incarceration for non violent drug offenders in the U SPresently there are moreDrug Treatment Courts operating nationwideThese courts take a collaborativenon adversarialteam approach uniting the judgeprosecution and defense attorneys with substance abuse treatment professionals to facilitate effective drug treat ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health