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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Advancing a Glioma Immunotherapy
SBC: IN CYTU, INC. Topic: 102DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...
SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
High-potency nitro antimicrobials for topical treatment of trichomoniasis
SBC: DESIGNMEDIX, INC. Topic: RDESCRIPTION provided by applicant Trichomonas vaginalis is the causative agent of the most common non viral sexually transmitted infection with million new cases reported annually in the world and million cases in the U S In addition to infections of the urogenital tract trichomoniasis increases the risk of adverse pregnancy outcomes and HIV transmission and increases the incidence ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Development of DRα1-MOG-35-55 for treatment of DR2 negative MS subjects
SBC: VIROGENOMICS BIODEVELOPMENT INC Topic: NIAIDDESCRIPTION provided by applicant Our laboratory discovered and is developing partial p MHC class II constructs pMHC as a possible immunotherapy for multiple sclerosis MS pMHC containing the extracellular domains of the MS risk factor HLA DR linked covalently to the encephalitogenic peptide of myelin oligodendrocyte glycoprotein pDR MOG can reverse CNS inflammation and ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Peripheral Nerve-on-a-chip for Predictive Preclinical Pharmaceutical Testing
SBC: AXOSIM, INC. Topic: NCATSDESCRIPTION provided by applicant The drug development pipeline is plagued by unacceptable rates of attrition due in large part to toxicities that are not identified in pre clincal stages of development The ability to de risk lead compounds during pre clinical development with advanced andquot organoid on a chipandquot technologies show tremendous promise Chemotherapeutics in particular whi ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Development of nucleic acid delivery platform based on polymeric CXCR4 antagonists
SBC: Bohemica Pharmaceuticals, LLC Topic: 100DESCRIPTION provided by applicant Therapeutics based on nucleic acids NA promise to revolutionize treatment of multiple diseases but their widespread use is currently limited by the lack of efficient delivery methods We have recently developed a new NA delivery platform based on polymeric CXCR inhibitors PCX suitable as dual function systems for simultaneous NA delivery and inhibition of ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Mutation Enriched Targeted Re Sequencing
SBC: TRANSGENOMIC, INC. Topic: 103DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza
SBC: EPIVAX, INC. Topic: NIAIDDESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...
SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Phase I Clinical trial with Demethyl cholesteryloxycarbonylpenclomedine DM CHOC PEN in Children with Cancer Involving the CNS
SBC: DEKK-TEC INC Topic: 102DESCRIPTION provided by applicant The primary goal of this Phase I pediatric oncology clinical trial will be to evaluate the safety and use of demethyl cholesteryloxycarbonylpenclomedine DM CHOC PEN as anticancer therapy for children with advanced cancer involving the central nervous system CNS DM CHOC PEN is a polychlorinated pyridine cholesteryloxycarbonate that crosses the blood br ...
SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Advancing Human Health by Lowering Barriers to Electrophysiology in Genetic Model Organisms
SBC: NEMAMETRIX, INC Topic: 300DESCRIPTION provided by applicant The nematode Caenorhabditis elegans is a powerful experimental system that is widely used as a model for a large number of high impact medical conditions from aging and metabolic disorders to neurodegenerative diseases The strength of this microscopic worm as a medical model derives from the extensive genetic homology between nematodes and humans together ...
SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
ESCALA (Escuela y Carrera Latina/Latino School and Career)
SBC: IRIS MEDIA INC Topic: NIMHDDESCRIPTION provided by applicant The proposed project will develop ESCALA Escuela y Carrera Latina Latino School and Career a mobile web app designed to increase the college and lowest educational attainment in the United States Because educational attainment is a major social determinant of health it is not surprising that Latinos also experience poor health outcomes compared to white ...
SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health