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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Goldmann Contact Tonometry with Optimized Error Correction

    SBC: INTUOR TECHNOLOGIES LLC            Topic: N

    DESCRIPTION provided by applicant Intraocular pressure IOP is arguably the second most important criteria used to assess visual acuity when eye care professionals are diagnosing treating and managing patients The patented Intuor Applanation Tonometer IAT prism design is a novel and simple approach for improving the accuracy of IOP measurement in the eye The proposal describes an inexpen ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. B7-H3-Targeted Contrast Agent for Ultrasonic Imaging of Breast Cancer

    SBC: NUVOX PHARMA, L.L.C.            Topic: 102

    ABSTRACT Breast cancer is the second leading cause of cancer deaths in women in the United States and early detection can help improve survival While mammography is the current first line imaging technique for early breast cancer detection its diagnostic accuracy is limited in women with dense breast tissue Ultrasound is often performed as a second line test in women with dense breast tissue H ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Ultrahigh Performance Non-Denaturing Protein Chromatography Columns

    SBC: BIOVIDRIA, INC.            Topic: 400

    PROJECT SUMMARY The proposed product is an analytical scale UHPLC column for separating protein drugs in native form with the Phase I proposal focused on anion exchange chromatography as the separation mechanism The bonded phase is made of polymer chains in this case bearing weak anion exchange groups The study will be expanded to cation exchange and hydrophobic interaction chromatography in ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Development of Chol-DsiRNA Polyplexes to Improve the Therapy of Breast Cancer

    SBC: ACTORIUS PHARMACEUTICALS, LLC            Topic: 100

    DESCRIPTION provided by applicant Breast cancer is the most common type of cancer in women between the ages of and and responsible for deaths annually If treated early five year survival rates for patients in the U S are between and but drop to once metastatic breast cancer has developed Thus there is a great need to develop more effective treatment strategies fo ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. In Situ Autovaccination against Solid Cancers with Intratumoral Hiltonol Poly ICLC A phase II Adaptive Multicenter Clinical Study

    SBC: Oncovir            Topic: 102

    DESCRIPTION provided by applicant Hiltonol poly ICLC is a stabilized dsRNA therapeutic viral mimic or andapos danger signalandapos that activates multiple elements of innate and adaptive immunity It is a standalone immunomodulator but when properly combined with antigen it generates a comprehensive Th weighted immune response best suited for antiviral and antitumor action This project ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Ultrasensitive SERS Nano-Sensors for Pancreatic Cancer Diagnosis and Prognosis

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 103

    ABSTRACT Pancreatic cancer PC is an extremely aggressive malignancy with one of the worst prognoses of all cancers with a median survival of less than one year and an overall year survival of andlt With marked resistance to chemo and radiotherapies surgery is the only curative option In patients with localized disease and no lymph node or extra pancreatic metastases complete surgical ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Combinatorial Inactivation of ERBB Receptors in Breast Cancer using Therapeutic Stapled Peptides

    SBC: ARIZONA CANCER THERAPEUTICS L.L.C.            Topic: 103

    DESCRIPTION provided by applicant In metastatic breast cancer the Epidermal Growth Factor Receptor family of transmembrane tyrosine kinases ErbB drives proliferation and metastasis EGFR HER and ErbB are known to be highly expressed and active in both the HER and Triple Negative Basal subtypes of breast cancer and have been targeted with varying effectiveness Importantly targeting of ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Routinizing HIV testing for Adolescents

    SBC: MEDIA REZ LLC            Topic: NICHD

    DESCRIPTION provided by applicant This study will aim to assess the feasibility and acceptability of using state of the art social media and game technology to increase HIV testing among adolescents and young adults AYA ages Rates of HIV testing among AYA are low resulting in high proportions of AYA who are positive or unaware of their HIV infection Further public health messages wh ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Targeted and Non-targeted Microbubbles for Pediatric Applications

    SBC: NUVOX PHARMA, L.L.C.            Topic: NICHD

    Project Summary Staphylococcus is the most common cause of community and hospital acquired infective endocarditis worldwide Staphylococcal S aureus endocarditis is a serious health problem in children and adults that carries high morbidity and mortality The incidence of this disease is increasing due to healthcare advances with widespread use ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Point of care immunoassay for rapid diagnosis of tinea capitis

    SBC: DXDISCOVERY INC            Topic: NIBIB

    Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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