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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Advancing a Glioma Immunotherapy

    SBC: IN CYTU, INC.            Topic: 102

    DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Novel DFG out inhibitors of Abl-kinases to treat PML

    SBC: Inhibikase Therapeutics, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Inhibikase Therapeutics is a clinical stage biopharmaceutical company that has developed a host targeted mechanism of action to treat AIDS related and drug induced progressive multifocal leukoencephalopathy PML PML is a demyelinating disease of the central nervous system and was rarely seen clinically until the era of the HIV epidemic began in the mid s During the ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Development of nucleic acid delivery platform based on polymeric CXCR4 antagonists

    SBC: Bohemica Pharmaceuticals, LLC            Topic: 100

    DESCRIPTION provided by applicant Therapeutics based on nucleic acids NA promise to revolutionize treatment of multiple diseases but their widespread use is currently limited by the lack of efficient delivery methods We have recently developed a new NA delivery platform based on polymeric CXCR inhibitors PCX suitable as dual function systems for simultaneous NA delivery and inhibition of ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Online resource center for older adults with cochlear implants

    SBC: KDH Research & Communication, Inc.            Topic: NIDCD

    In this Phase I proposal resubmission KDH Research andamp Communication KDHRC proposes to develop and evaluate the Online Resource Center for Older Adults with Cochlear Implants RCCI RCCI will be an innovative web based resource center for older adults aged with cochlear implants CIs and their family members for age related hearing loss RCCI will provide high quality information ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Nanotechnology-Based Environmental Smart Sensors for Personal Health Exposure Monitoring

    SBC: WI-SENSE LLC            Topic: NIEHS

    DESCRIPTION provided by applicant A broad goal of the proposed research is to develop personal exposure monitors comprising wearable wireless sensor arrays to detect harmful air pollutants within the breathing zone and improve the assessment of causative exposure dose response relationships in epidemiological studies Heterogeneous orthogonal detectors comprising functionalized carbon nanotub ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Cryopreserved Adherent Neural Cell Assay Plates

    SBC: ARUNA BIO, INC.            Topic: 113

    DESCRIPTION provided by applicant Neural progenitor migration is an important process for the proper development and maintenance of the nervous system Derived from proliferative zones within the brain neural progenitors migrate to specific destinations guided by various extracellular cues Exposure to neurotoxicants during development can interfere with neural progenitor migration and lead to ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Improving the HIV testing experience for YMSM

    SBC: VIRTUALLY BETTER INC            Topic: NICHD

    DESCRIPTION provided by applicant Young men who have sex with men YMSM are the only risk group with a rising incidence of HIV infection yet a high proportion of HIV infected YMSM are unaware of their seropositive status HIV testing is the critical first component of HIV prevention and care Individuals who are aware of their infection can begin treatment which can reduce the likelihood of ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Routinizing HIV testing for Adolescents

    SBC: MEDIA REZ LLC            Topic: NICHD

    DESCRIPTION provided by applicant This study will aim to assess the feasibility and acceptability of using state of the art social media and game technology to increase HIV testing among adolescents and young adults AYA ages Rates of HIV testing among AYA are low resulting in high proportions of AYA who are positive or unaware of their HIV infection Further public health messages wh ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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