Award Data

Despite significance advances in anti retroviral treatments HIV associated neurocognitive disorder HAND remains prevalent and can affect a broad range of everyday activities An effective brief cognitive screen that could be implemented in busy HIV clinics where clinicians have limited time to provide care for patients with complex medical psychiatric and cognitive conditions has the poten ...

DESCRIPTION provided by applicant During the last decade the quantity of bioimaging data has grown tremendously Current estimates indicate that the average hospital in the USA houses some TB of data of which approximately is composed of unstructured image data from CT MRI and X ray machines This huge quantity of data is expected to grow at a rate of annually meaning hospita ...

DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...

Project Summary Abstract Every year approximately severe mistreatments happen in radiation therapy Radiation therapy lawsuits rank in the top third of all medical specialties with an average of $ per claim settled or litigated The current method for detecting treatment errors is by a weekly patient chart check where each treatment record is manually reviewed on a weekly basis Thi ...

DESCRIPTION provided by applicant We present a new family of contrast agents based on targeting the maltodextrin transporter termed maltodextrin based imaging probes MDPs which are designed to image infections associated with implanted medical devices by fluorescent imaging The chemical structure of an MDP is composed of maltodextrins conjugated to the positron emitting radioelement fluori ...

PROJECT SUMMARY ABSTRACT Among men prostate cancer is the most common non skin cancer and second leading cause of cancer death with over new diagnoses expected in Approximately of men will be diagnosed with prostate cancer in their lifetime Current treatment options for prostate cancer however have sub optimal incidences of side effects that have a significant impact on pa ...

Smoking is the most common preventable cause of morbidity and mortality in the United States Each year smoking causes the premature death of over Americans and $ billion of economic damage Effective treatment is possible but barriers to its implementation limits the success rate of smoking cessation in the general population to about Notably reward based incentive smoking cessat ...

DESCRIPTION provided by applicant Smoking is the most common preventable cause of morbidity and mortality in the United States For of adult smokers this addiction began in adolescence Effective interventions to block the escalation of this initial smoking in adolescents exist However the implementation and effectiveness of these interventions are hindered by the inability of current bi ...

DESCRIPTION provided by applicant Neural progenitor migration is an important process for the proper development and maintenance of the nervous system Derived from proliferative zones within the brain neural progenitors migrate to specific destinations guided by various extracellular cues Exposure to neurotoxicants during development can interfere with neural progenitor migration and lead to ...

DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...