Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Optimization of the Production and Isolation of the Novel Antifungal Occidiofungin

    SBC: Sano Chemicals, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar fungicidal activity against a broad spectrum of fungi Occidiofungin is produced by the Gram negative bacterium Burkholderia contaminans From our structural characterization studies occidiofungin was determined to have a unique chemical composition Our studies have als ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Optimized lactoferrin for treatment of intracerebral hemorrhage

    SBC: PHARMAREVIEW CORPORATION            Topic: 101

    DESCRIPTION provided by applicant Intracerebral hemorrhage ICH is a major public health problem with the highest mortality rate of all stroke subtypes ICH is one of the leading causes of long term disability Since there are no available FDA approved therapies for ICH it is of vast importance to search for new approaches in treatment for this devastating medical condition Lactoferrin LT ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Nanotechnology-Based Environmental Smart Sensors for Personal Health Exposure Monitoring

    SBC: Wi-Sense LLC            Topic: NIEHS

    DESCRIPTION provided by applicant A broad goal of the proposed research is to develop personal exposure monitors comprising wearable wireless sensor arrays to detect harmful air pollutants within the breathing zone and improve the assessment of causative exposure dose response relationships in epidemiological studies Heterogeneous orthogonal detectors comprising functionalized carbon nanotub ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Microhook nerve tape A nerve repair coaptation aid

    SBC: Axion Biosystems, Inc.            Topic: 105

    DESCRIPTION provided by applicant This proposed project will develop and validate a microhook based nerve tape device for quick and effective repair of nerve injuries The microhook wrap consists of an array of microscale hooks distributed across a fine flexible meshwork and embedded in a biocompatible backing material This nerve tape will be used during nerve repair surgeries in place of mi ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Enhancing protective antibody responses for a DNA MVA HIV vaccine

    SBC: GEOVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The proposed work addresses a pivotal study for decisions on the form of the GeoVax Clade B HIV vaccine GOVX B to be taken into efficacy trials GOVX B is a DNA MVA vaccine that expresses virus like particles VLPs displaying trimeric membrane bound Env It has been under development for more than years during which time it has demonstrated unique pr ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. LASER TISSUE WELDING BREACHING BARRIERS IN THE SURGICAL MANAGEMENT OF THE PANCREAS

    SBC: Laser Tissue Welding, Inc            Topic: 102

    DESCRIPTION provided by applicant The pancreas is one of the most challenging organs from a surgical perspective and there is no technology available that effectively seals this organ after resection The development of pancreatic leakage and fistula is the single most significant cause of morbidity and mortality after pancreatectomy and abdominal sepsis occurs in of the postoperati ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. I Live Inspired Individually Tailored and Integrated Social Support Network for Tobacco Cessation

    SBC: Live Inspired, LLC            Topic: NIDA

    DESCRIPTION provided by applicant Smoking kills Americans annually exacerbates myriad diseases and costs billions in healthcare and productivity losses Numerous barriers exist to accessing traditional treatment e g costs traveling to and scheduling appointments other logistics Text messaging is an extremely popular communication method Over of all Americans use text m ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Portable nanofluidic aptamer SERS instrument for measurement of chemical exposure

    SBC: Biotex, Inc.            Topic: NIEHS

    DESCRIPTION provided by applicant The goal of this NIH SBIR Phase II effort is to develop a new point of care POC detection platform and methodology for assessment of human exposure to hazardous environmental compounds in the bloodstream Because the mechanisms of transport of such chemicals into the body their differing stabilities and elimination are difficult to model it is much more st ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government