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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Production of Image Guided Metastatic Melanoma Therapy Radiopharmaceuticals

    SBC: VIEWPOINT MOLECULAR TARGETING, LLC            Topic: 102

    DESCRIPTION provided by applicant Melanoma the fastest growing cancer incidence in the world today and the American Cancer Society reports that death rates for melanoma continue to rise Alarmingly melanoma is the most common cancer in young adults under One characteristic of metastatic melanoma cells that is recognized as a potential target for new therapies is upregulation of cell surfac ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Quantitative PCR Platform for The Assessment of Alcohol Consumption

    SBC: BEHAVIORAL DIAGNOSTICS, INC.            Topic: NIAAA

    DESCRIPTION provided by applicant Heavy alcohol use is common and presents a major social economic challenge Although chronic use of small amounts of alcohol is not always harmful heavier use andgt drinks day is generally harmful and frequently leads to alcoholism or as it is termed in ICD Alcohol Use Disorder AUD AUD affects of the U S population and causes over $ billio ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Multi Source E Beam kV X Ray Tube for Image Guided Radiotheraphy

    SBC: TELESECURITY SCIENCES, INC.            Topic: 102

    DESCRIPTION provided by applicant This project will develop a commercial product that will enable for the first time realtime tumor tracking during radiotherapy at an attractive price point and with minimal interference with standard clinical practice The key novel technology is an optimized multi source X ray tube with focal spots that is placed below the multi leaf collimator MLC of a r ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. I Live Inspired Individually Tailored and Integrated Social Support Network for Tobacco Cessation

    SBC: Live Inspired, LLC            Topic: NIDA

    DESCRIPTION provided by applicant Smoking kills Americans annually exacerbates myriad diseases and costs billions in healthcare and productivity losses Numerous barriers exist to accessing traditional treatment e g costs traveling to and scheduling appointments other logistics Text messaging is an extremely popular communication method Over of all Americans use text m ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. An Automated Patient Chart Error Detection System for Radiation Therapy

    SBC: Infondrian LLC            Topic: 101

    Project Summary Abstract Every year approximately severe mistreatments happen in radiation therapy Radiation therapy lawsuits rank in the top third of all medical specialties with an average of $ per claim settled or litigated The current method for detecting treatment errors is by a weekly patient chart check where each treatment record is manually reviewed on a weekly basis Thi ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Point of care immunoassay for rapid diagnosis of tinea capitis

    SBC: DxDiscovery Incorporated            Topic: NIBIB

    Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. A Quantitative Epigenetic Test for Guiding Smoking Cessation Therapy

    SBC: BEHAVIORAL DIAGNOSTICS, INC.            Topic: NCI

    Smoking is the most common preventable cause of morbidity and mortality in the United States Each year smoking causes the premature death of over Americans and $ billion of economic damage Effective treatment is possible but barriers to its implementation limits the success rate of smoking cessation in the general population to about Notably reward based incentive smoking cessat ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. In Situ Autovaccination against Solid Cancers with Intratumoral Hiltonol Poly ICLC A phase II Adaptive Multicenter Clinical Study

    SBC: Oncovir            Topic: 102

    DESCRIPTION provided by applicant Hiltonol poly ICLC is a stabilized dsRNA therapeutic viral mimic or andapos danger signalandapos that activates multiple elements of innate and adaptive immunity It is a standalone immunomodulator but when properly combined with antigen it generates a comprehensive Th weighted immune response best suited for antiviral and antitumor action This project ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health

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