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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Advancing a Glioma Immunotherapy

    SBC: IN CYTU, INC.            Topic: 102

    DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Development of nucleic acid delivery platform based on polymeric CXCR4 antagonists

    SBC: Bohemica Pharmaceuticals, LLC            Topic: 100

    DESCRIPTION provided by applicant Therapeutics based on nucleic acids NA promise to revolutionize treatment of multiple diseases but their widespread use is currently limited by the lack of efficient delivery methods We have recently developed a new NA delivery platform based on polymeric CXCR inhibitors PCX suitable as dual function systems for simultaneous NA delivery and inhibition of ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Monitored Breathing Awareness Therapy for Insomnia Disorder in Older Adults

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: NIA

    DESCRIPTION provided by applicant Insomnia of sufficient clinical severity to meet diagnostic criteria is present in approximately of older adults nearly million individuals n the US alone If left untreated it can lead to increased rates of depression cognitive impairment and cardiovascular disease Treatment relies on pharmacotherapy such as sedative hypnotic therapy which is ass ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Medical Sensor Applications of Tunnel Magnetoresistance TMR

    SBC: Koronis Biomedical Technologies Corp.            Topic: NIDCD

    DESCRIPTION provided by applicant Koronis Biomedical Technologies KBT proposes to develop a novel omnidirectional low power miniaturized hearing aid telecoil replacement module TCRM based on tunneling magnetoresistance TMR technology It has been reported that million Americans have hearing loss Hearing loss affects in Americans and in households Modern telecoils assist ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Advanced Magnetic Pickup Hearing Aids

    SBC: NVE CORP. (FORMERLY NONVOLATILE ELECTRONICS, INC.            Topic: Y

    DESCRIPTION provided by applicant The goal of this Small Business Innovative Research project proposed to the National Institutes of Health in particular the National Institute on Deafness and Other Communication Disorders is the creation of a superior signal receiving component in hearing aids The proposed advanced magnetic field pickup will increase the potential to wirelessly link the hea ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Development of BIO as a MCM for lethal radiation pneumonitis fibrosis

    SBC: Humanetics Corporation            Topic: R

    Project Summary A significant need exists for effective medical countermeasures for radiation induced pneumonitis and pulmonary fibrosis associated with the delayed effects of acute radiation exposure Of great importance are countermeasures that can be distributed for use without medical supervision making orally effective countermeasures of high interest and importance To address this unmet ne ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Generating a Porcine Model for Human Microvillus Inclusion Disease (MVID) by Gene Editing

    SBC: Recombinetics, Inc.            Topic: 300

    DESCRIPTION provided by applicant Microvillus inclusion disease MVID is the most severe cause of Congenital Diarrheal Diseases in neonates MVID results from mutations that lead to malabsorption and life threatening intractable secretory diarrhea To date no curative therapy exists MVID patients are largely dependent on parenteral nutrition Prognosis is generally poor due to metabolic d ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Semi-autonomous Robotic Powered Wheelchair Functionality

    SBC: Innovative Design Labs Inc.            Topic: NICHD

    DESCRIPTION provided by applicant Mobility limitations are the leading cause of functional limitations among adults and are strong predictors of activities of daily living ADL Impaired mobility often results in decreased opportunities to socialize and can lead to social isolation anxiety and depression There are many impairments for which driving a powered wheelchair can be a challenge in ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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