Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Novel Trypanocidal Compounds for the Treatment of Stage and HAT

    SBC: MEDISYNERGICS, LLC            Topic: R

    DESCRIPTION provided by applicant Human African Trypanosomiasis HAT is a disease caused by a parasitic organism trypanosoma brucei It is often referred to as andquot sleeping sicknessandquot because of the symptoms that emerge in Stage patients The disease exists in two forms depending on the causative parasite Trypanosoma brucei gambiense or Trypanosoma brucei rhodesiense T b gamb ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Malarial Retinopathy Screening System for Improved Diagnosis of Cerebral Malaria

    SBC: Visionquest Biomedical LLC            Topic: NIAID

    DESCRIPTION provided by applicant Cerebral malaria CM is a life threatening neurological complication associated with malarial infection Malaria affects about million people worldwide and claims lives annually of whom are African children under years of age CM is mistakenly over diagnosed about of the time in which the cases of concurrent non CM diseases with simil ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Androgen Receptor Degraders to Treat Castration Resistant Prostate Cancer

    SBC: Arvinas, Inc            Topic: 102

    DESCRIPTION provided by applicant The overall aim of this grant is to generate data to understand and enable the development of a novel therapeutic approach for the treatment of patients with castration resistant prostate cancer Prostate cancer is the third most lethal cancer in the US with new cases and deaths projected to occur in While early detection surgery and horm ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. I Live Inspired Individually Tailored and Integrated Social Support Network for Tobacco Cessation

    SBC: Live Inspired, LLC            Topic: NIDA

    DESCRIPTION provided by applicant Smoking kills Americans annually exacerbates myriad diseases and costs billions in healthcare and productivity losses Numerous barriers exist to accessing traditional treatment e g costs traveling to and scheduling appointments other logistics Text messaging is an extremely popular communication method Over of all Americans use text m ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. A high volume parallel acoustic flow cytometer for the detection of rare cells or particles in a large sample volume with a low background concentration i e very dilute samples

    SBC: ETA DIAGNOSTICS, INC            Topic: 400

    DESCRIPTION provided by applicant Many biomedical applications require the detection of rare cells or particles in large sample volumes These applications can be divided into those that require the detection of highly dilute cells in a large sample volume and those that require the detection of rare cells in a high background concentration of similar cells within a large volume Though flow cy ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Point of care immunoassay for rapid diagnosis of tinea capitis

    SBC: DxDiscovery Incorporated            Topic: NIBIB

    Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. In Situ Autovaccination against Solid Cancers with Intratumoral Hiltonol Poly ICLC A phase II Adaptive Multicenter Clinical Study

    SBC: Oncovir            Topic: 102

    DESCRIPTION provided by applicant Hiltonol poly ICLC is a stabilized dsRNA therapeutic viral mimic or andapos danger signalandapos that activates multiple elements of innate and adaptive immunity It is a standalone immunomodulator but when properly combined with antigen it generates a comprehensive Th weighted immune response best suited for antiviral and antitumor action This project ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Quantitative Biomarkers of T D Peripheral Neuropathy using Functional Imaging

    SBC: Visionquest Biomedical LLC            Topic: 200

    Summary The objective of this project is to validate the i RxTherm VisionQuest s patented functional thermal imaging system that produces biomarkers for early detection of diabetic peripheral neuropathy DPN This device is based on the principle that changes in microvascular function are correlated to quantifiable changes in nerve function as expressed in measureable microvascular changes Dia ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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