Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Structure activity relationship of small molecule inhibitors of human papillomavirus E protein will be tested

    SBC: SUNNYLIFE PHARMA INC.            Topic: NIAID

    The human papillomavirus HPV E protein is needed for viral replication Infection with high risk HPV types can progress to pre malignant lesions called dysplasias which over a period of years can eventuate in invasive and metastatic epithelial malignancies HPV E proteins bind to the ubiquitin ligase E AP and this complex targets p and other E binding proteins for proteasome mediated de ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Commercialization of a serum diagnostic for detection of Alzheimer s Disease

    SBC: Arkley BioTek, LLC            Topic: NIA

    DESCRIPTION provided by applicant Commercialization of a blood diagnostic for early detection of Alzheimerandapos s Disease The goal of this research is to demonstrate proof of concept in being able to utilize a disease marker in the blood to develop a diagnostic andapos testandapos for the early detection and staging of Alzheimerandapos s disease AD AD is a chronic neurodegenerative disea ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Malarial Retinopathy Screening System for Improved Diagnosis of Cerebral Malaria

    SBC: Visionquest Biomedical LLC            Topic: NIAID

    DESCRIPTION provided by applicant Cerebral malaria CM is a life threatening neurological complication associated with malarial infection Malaria affects about million people worldwide and claims lives annually of whom are African children under years of age CM is mistakenly over diagnosed about of the time in which the cases of concurrent non CM diseases with simil ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Telehealth Platform for Treatment with the SpeechVive Device

    SBC: SpeechVive, Inc.            Topic: Y

    DESCRIPTION provided by applicant The majority of people with Parkinsonandapos s disease PD experience communication impairments which impact all aspects of daily life leading to social isolation and reduced quality of life Because of difficulties in accessing speech therapy only a very small percentage of people with PD participate in these treatments during their disease An easily acce ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. I Live Inspired Individually Tailored and Integrated Social Support Network for Tobacco Cessation

    SBC: Live Inspired, LLC            Topic: NIDA

    DESCRIPTION provided by applicant Smoking kills Americans annually exacerbates myriad diseases and costs billions in healthcare and productivity losses Numerous barriers exist to accessing traditional treatment e g costs traveling to and scheduling appointments other logistics Text messaging is an extremely popular communication method Over of all Americans use text m ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. A high volume parallel acoustic flow cytometer for the detection of rare cells or particles in a large sample volume with a low background concentration i e very dilute samples

    SBC: ETA DIAGNOSTICS, INC            Topic: 400

    DESCRIPTION provided by applicant Many biomedical applications require the detection of rare cells or particles in large sample volumes These applications can be divided into those that require the detection of highly dilute cells in a large sample volume and those that require the detection of rare cells in a high background concentration of similar cells within a large volume Though flow cy ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Point of care immunoassay for rapid diagnosis of tinea capitis

    SBC: DxDiscovery Incorporated            Topic: NIBIB

    Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. In Situ Autovaccination against Solid Cancers with Intratumoral Hiltonol Poly ICLC A phase II Adaptive Multicenter Clinical Study

    SBC: Oncovir            Topic: 102

    DESCRIPTION provided by applicant Hiltonol poly ICLC is a stabilized dsRNA therapeutic viral mimic or andapos danger signalandapos that activates multiple elements of innate and adaptive immunity It is a standalone immunomodulator but when properly combined with antigen it generates a comprehensive Th weighted immune response best suited for antiviral and antitumor action This project ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government