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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Noninvasive Functional Cortical Mapping with Innovative tEEG

    SBC: CREMEDICAL CORP            Topic: 106

    PROJECT SUMMARY Resective neurosurgery is essential for treating a range of neurologic conditions such as epilepsy and brain tumorsFor some patientswhose lesion is close to cortical language areaspostoperative expressive or receptive language deficit is a major and feared postoperative complicationMuch effort is devoted to identifying the cortical language regionsand relating such localization to ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A multivalent, easy-to-use product to mitigate and treat radiation exposure

    SBC: FIBROPLATE INC            Topic: NIAID

    ABSTRACTThe threat of radiological and nuclear accidents or attacks demands for effective radiation medical countermeasuresMCMable to mitigate and treat the effects of exposure to ionizing radiationsHematopoietic acute radiation syndromeHRASand cutaneous radiation syndromeCRSpose severelife threatening risks to exposed individualsCurrently no effective radio mitigatorto be administered after radia ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Combinatorial Biomarkers for Malignant Polyps and Colon Cancer Detection

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 102

    ABSTRACT Technological advancements in colonoscopic and polypectomy procedures have drastically reduced both the incidence and overall mortality due to colorectal cancerCRCHowevereven with the availability of multiple screening toolsonlyof CRC are diagnosed at early stagein part due to lack of compliance with follow up colonoscopy procedurelimited access to colonoscopyThese factors contribute to i ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Immunoassay for early diagnosis of mucormycosis

    SBC: DXDISCOVERY INC            Topic: NIAID

    Mucormycosis is one of the deadliest of the invasive fungal infections. Mucormycosis occurs most often in patients with hematological malignancies undergoing chemotherapy, patients who have received hematopoietic stem cell transplants or patients with diabetes mellitus. Improved diagnosis is the most frequently noted unmet need for management of the mucormycosis patient. Delays in treatment increa ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Developing, Testing and Validating a Wearable Alcohol Biosensor

    SBC: Clinitech, LLC            Topic: 450

    1 PROJECT SUMMARY2 This application for a Phase II SBIR award extends the successful completion of Phase I and represents a 3 collaboration between Clinitech, LLC and McLean Hospital/Harvard Medical School to continue the4 development of a wearable biosensor for detecting alcohol in the interstitial fluid of humans. Excessive use of5 alcohol accounts for much of the public health burden related to ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Soluble, solution-stable phospho-glucagon for hypoglycemic rescue

    SBC: MONON BIOVENTURES LLC            Topic: 200

    PROJECT SUMMARY Hypoglycemiaa decrease in blood sugar levelsis a common occurrence for themillion Americans with diabetesIn severe hypoglycemiathe individual is at risk for diabetic coma and even deathAlthough these events can be managed using a glucagon emergency kitcurrent kits require a multi step procedure in which lyophilized glucagon is reconstituted and administered as an injectionEmergency ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. A Novel Probiotic Platform to Treat Necrotizing Enterocolitis

    SBC: Scioto Biosciences Inc.            Topic: 300

    PROJECT SUMMARY Necrotizing enterocolitis (NEC) is a devastating disease affecting premature infants. Approximately 10% of infants born under 1500 g will develop the disease, and mortality for affected infants is 20-30%. Despite decades of research, the morbidity and mortality of the disease remain generally unchanged. Current treatment and preventive approaches for NEC remain suboptimal, with no ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Improving treatment options and outcomes in fungal keratitis

    SBC: TranZ Biosciences LLC            Topic: N

    ABSTRACT Fungal keratitisprimarily caused by CandidaFusariumor Aspergillus speciesis a leading cause of blindness among corneal diseasesAmphotericin BAmBremains the gold standard in the treatment of Candida keratitis and is also the fallback option for other corneal fungal infectionsAlthough widely used off label in ocular infectionsophthalmic AmB formulations are not available commerciallyThe com ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Prevention of White Matter Injury in Premature Infants

    SBC: Medosome Biotec, LLC            Topic: NICHD

    ABSTRACTUp toof low birth weight preterm infants manifest some form of periventricular white matter injuryPWMImaking it the most common form of brain injury affecting premature infantsPWMI is associated with significant morbidityas affected individuals may have profound intellectual impairment and cerebral palsyHighlighting the magnitude of PWMIeach year more thaninfants are born prematurely in th ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Development of non-invasive research and diagnostics platform for Alzheimer's disease based on plasma exosomes

    SBC: TYMORA ANALYTICAL OPERATIONS LLC            Topic: N

    PROJECT SUMMARY Almostmillion Americans currently live with Alzheimerandapos s diseaseADand this number is projected to increase tomillion byThe consensus is arising in the field that in order to treat AD effectivelyearly detection at the MCI stage is a mustThusthere is a critical need for a novel minimally invasive and cost effective diagnostic assay capable of such early detectionCell secreted e ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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