Award Data

Onda Vision Technologies Inc (OVT) in collaboration with the University of Florida (UF)proposes to address the problem of heat-related illness (HRI) in farmworkers. This proposalsupports the United States Department of Agricultural (USDA) research interests in developingnew tools to enhance farm safety.This Small Business Innovation Research Phase I Project determines the feasibility of developing ...

PROJECT SUMMARY Title: SMoLDER: Situational awareness ModeLing and Decision support Engine for wildfire Response PD: Koplik Gary J. Institution: Geometric Data Analytics Inc. In 2020 58950 wildfires burned 10.1 million acres one of the highest acreage impacts in recorded history. Wildland firefighters particularly those in remote environments often rely on basic tools such as paper maps compasses ...

Project Summary/AbstractFunding Opportunity Number: USDA-NIFA-SBIR-009301Topic Area 8.8: Biofuels and Biobased ProductsTitle of Project: Designer Biochar - Low-cost adsorbents and fertilizers for nitrate and phosphateadsorption and nutrient deliveryPD/PI: Brigano Frank A. Glanris Inc.Co PD/PI: Mlsna Todd E. Mississippi State UniversityCo PD/PI: Pittman Charles Mississippi State UniversityGlanris I ...

ABSTRACT The goal of this STTR proposal is to develop a novel anti-fibrotic agent suitable for oral administration which could be used to safely and effectively treat Systemic Sclerosis (SSc), or Systemic Scleroderma patients. SSc is one of the most disabling and lethal immune-mediated rheumatic disorders. SSc is a rare disease, affecting 40,000-150,000 people in the United States and conferring a ...

ABSTRACT Significant advances in the specific targeting of delivery vectors and the increased therapeutic efficacy of such vectors for gene delivery have been made, stimulating major interest in the development and commercialization of therapeutic products focused on gene therapy indications. CLAIRIgene LLC focused on the development and optimization of various viral gene-to-cell transfer delivery ...

PROJECT SUMMARY To achieve the FDA’s required Sterility Assurance Level for use in humans, pharmaceutical products must undergo terminal sterilization or aseptic manufacturing. This can be accomplished using physical or chemical methods such as heat or formaldehyde for simple drug formulations; however, for pharmaceutical products that have more complex drug formulations or that contain biologic ...

Abstract: A Therapeutic Role for Apolipoprotein-E in the Germ Theory of ADP. gingivalis is the keystone bacteria of periodontal disease, the 6th most common infectious disease worldwide. Half of all Americans over the age of 30 and 70% of those over age 65 suffer some degree of P. gingivalis infection associated with gum disease. In a study of 6800 patients with gum disease that were followed for ...

Adeno-associated virus (AAV) vectors have been successfully employed in patients with rare neurological diseases. Recently, two AAV based gene therapy drugs have been approved by the FDA, Luxturna been valued at $850,000 with a one-time application for blindness and Zolgensma at $2,100,000 for spinal muscle atrophy. AAV vector mediated gene therapy has shown to be a potentially huge market. Althou ...

PROJECT SUMMARY Diabetic Retinopathy (DR) is a serious diabetic complication that is the leading cause of vision loss in working- age adults, affecting more than 7.5 million people in the USA. It causes more new cases of blindness than any other eye disease in people between the ages of 18 and 65. The anti-VEGF treatments can slow the progress of DR in many patients but are only used after signifi ...

PROJECT SUMMARY/ABSTRACT Obstructive sleep apnea (OSA) and obesity hypoventilation syndrome (OHS) are the most common types of sleep disordered breathing (SDB). OSA is highly prevalent in the United States, affecting 20-40% of the adult population and more than 50% of individuals with obesity. Approximately 20% of individuals with obesity develop OHS defined as daytime hypercapnia and hypoventilat ...