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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. P-FITS: The Pediatric Food Intake Technology System

    SBC: Viocare, Inc.            Topic: NICHD

    Diet plays an integral role in the physical, emotional, and general health of children and adolescents. The consequences of poor diet during this critical time period are long-lasting, with nutritional status being a strong risk factor for chronic conditions throughout adolescence and adulthood. Current dietary assessment tools available for self-administration in older children are extremely limi ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. A point of care-device for the determination of creatinine phosphokinase (CPK), the CPK Now

    SBC: ANALYTICAL DIAGNOSTIC SOLUTIONS INC            Topic: NICHD

    AbstractThis application is in regard to the National Center for Advancing Translational Sciences SBIR/STTR Omnibus Solicitation. In Vitro Diagnostic Solutions, LLC (IVDS) proposes to develop a point-of-care test (POCT) to rapidly determine blood creatine phosphokinase (CPK) activity for the improved management of long-chain fatty acid oxidation disorders (LCFAODs). FAODs are inborn errors of meta ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Oscillating Magnetic Field Assisted Supercooling Preservation of Fresh and Unfrozen Ovaries at Subzero Temperatures

    SBC: JUN INNOVATIONS, INC.            Topic: NICHD

    PROJECT SUMMARY/ABSTRACT When the internal temperature of a material during freezing is below its equilibrium freezing point before ice nucleation has occurred, the material is said to be in the supercooled state. The long-term objective of this project is to develop a novel commercially viable supercooling device to preserve biological materials far below their freezing points while retaining the ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Inter-alpha Inhibitors in Experimental Necrotizing Enterocolitis

    SBC: PROTHERA BIOLOGICS, INC.            Topic: NICHD

    Necrotizing enterocolitis (NEC) is a devastating acute inflammatory condition of the gastrointestinal tract resulting in intestinal necrosis, systemic sepsis and multi-system organ failure found mostly in infants born prematurely. Despite modern medical advances in the past decade, the etiology remains elusive and morbidity and mortality are still unacceptably high. It has been concluded that the ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Inter-alpha Inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, INC.            Topic: 105

    Perinatal brain injury resulting in mental retardation and cerebral palsy is the most severe disability in children and affects 40-148 in preterm and 1–2/1000 in full term infants. This places a huge burden on society, emphasizing the critical need for improved prevention/treatment strategies to decrease perinatal brain injury. Hypothermia (HT) is the only FDA approved therapy to attenuate brain ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Using Machine Learning and Blockchain Technology to Reduce Drug Diversion in Hospitals

    SBC: AUTONOMOUS HEALTHCARE INC            Topic: NIDA

    Based on an analysis, the volume of dosage lost due to diversion increased from 21 million in 2017 to 47 million in 2018, a 126% increase. Addressing the drug diversion problem is a multi-faceted problem involving many components ranging from provider training to implementation of hardware and software systems to manage access to controlled substances. However, despite recent improvements in contr ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: 100

    Abstract Duchenne Muscular Dystrophy (DMD) is a fatal muscle disease with an incidence of 1 in 5000 males. DMD results from mutations in the gene encoding dystrophin, a 427 kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and laminin in the extracellular matrix. The α7β1 integrin is a transmembrane linkage system in skeletal and card ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Recombinant E-NTPDase for shock

    SBC: Purine Pharmaceuticals Inc.            Topic: 300

    SUMMARYInflammation after ischemia and reperfusion injury secondary to hemorrhagic shock is responsible for significant mortality and morbidity in the United States. Available intravenous fluids administered at the incident scene to treat hypovolemic shock do not completely prevent ischemia and reperfusion injury. Re-initiation of blood flow causes activation of several inflammatory mediators, suc ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Development of an Atmospheric Plasma Generator for Nitrogen Fixation in Air

    SBC: AQUANIS, INC.            Topic: C5427b

    The conventional nitric acid manufacturing method uses natural gas as a feedstock for hydrogen and an energy intensive thermal process that emits a large amount of carbon dioxide. A new low-temperature plasma system, which can be driven electrically by a renewable or nuclear energy source, could reduce the energy consumed by the synthesis of nitric acid while eliminating the emission of greenhouse ...

    SBIR Phase II 2023 Department of Energy
  10. Automated Grid Interconnection Planning and Cost Estimation Tool

    SBC: MAKAI OCEAN ENGINEERING INC            Topic: C5417b

    As renewable energy and distributed energy generation increases on the nation’s grids, the integration costs increase, and optimization of grid interconnection becomes critical for project development. The existing methods used for systems level design, planning, and performance and cost modeling for interconnected grids remain a labor-intensive, lengthy, and highly iterative process. A demand e ...

    SBIR Phase II 2023 Department of Energy
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