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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Computer based Screening for Diabetic Retinopathy

    SBC: Visionquest Biomedical LLC            Topic: NEI

    Summary VisionQuest Biomedical LLC VisionQuest has developed a diabetic retinopathy DR screening system EyeStar enabled by automated screening software DR RACS that was developed under the EY Phase II SBIR project Our product provides immediate feedback to the physician on the state of diabetic eye disease without burdening an eye care specialist to review those cases without retin ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. An Internet Application for SMART Recovery

    SBC: Checkup and Choices LLC            Topic: 350

    The objective of this research project is to update a web application Overcoming Addictions OA and enable it to be efficiently used by treatment providers in addition to its current use by the general public OA is an abstinence focused cognitive behavioral intervention based on the four point program for SMART Recovery www smartrecovery org We have already demonstrated the effectiveness of ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Developing Testing and Validating a Wearable Alcohol Biosensor

    SBC: Clinitech, LLC            Topic: 450

    PROJECT SUMMARY This application for a Phase I SBIR award represents a collaboration between Clinitech LLC and McLean Hospital Harvard Medical School to develop a wearable biosensor for detecting alcohol in the interstitial fluid of humans who have consumed alcohol Excessive use of alcohol accounts for much of the public health burden related to alcohol use disorders including fetal ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. A wearable tech app for CheckupandChoices

    SBC: Checkup and Choices LLC            Topic: 450

    The objective of this research project is to develop a prototype app for wearable technology that will significantly enhance the effectiveness of our web based alcohol and drug intervention Checkupandamp Choices CC We have already demonstrated the effectiveness of CCandapos s components in four randomized clinical trials CC has been commercialized and is in use by the general public This pro ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Comprehensive Eye Evaluation Algorithm CEEvA

    SBC: Visionquest Biomedical LLC            Topic: M

    Summary The objective of this project is to develop the Comprehensive Eye Evaluation Algorithm CEEvA a system to achieve blindness prevention in a cost effective way CEEvA uses fundus images and available personal medical data in the electronic medical record medical history and laboratory tests to automatically screen not only for DR but also for POAG and AMD in populations at higher risks ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Laboratory Bench Top EXAFS with STJ Spectrometer

    SBC: STAR CRYOELECTRONICS LLC            Topic: 100

    Project Summary Extended X ray absorption fine structure EXAFS is a technique that gives element specific structural and chemical information about molecules EXAFS currently requires bright X ray beams from specialized synchrotron light sources for most samples and so its applications are limited by access to these facilities This project will involve improved X ray detectors based on superco ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. An Internet Application for SMART Recovery

    SBC: Checkup and Choices LLC            Topic: 350

    The objective of this research project is to update a web application Overcoming Addictions OA and enable it to be efficiently used by treatment providers in addition to its current use by the general public OA is an abstinence focused cognitive behavioral intervention based on the four point program for SMART Recovery www smartrecovery org We have already demonstrated the effectiveness of ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Quantitative Biomarkers of T D Peripheral Neuropathy using Functional Imaging

    SBC: Visionquest Biomedical LLC            Topic: 200

    Summary The objective of this project is to validate the i RxTherm VisionQuest s patented functional thermal imaging system that produces biomarkers for early detection of diabetic peripheral neuropathy DPN This device is based on the principle that changes in microvascular function are correlated to quantifiable changes in nerve function as expressed in measureable microvascular changes Dia ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Point of care immunoassay for rapid diagnosis of tinea capitis

    SBC: DxDiscovery Incorporated            Topic: NIBIB

    Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health

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