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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Fourth Trimester- A web-based tool for Postpartum Care to Address the Needs of Underserved Women

    SBC: Orange Square Design, Inc.            Topic: NIMHD

    PROJECT SUMMARY ABSTRACT In the United Statesthe postpartum period is a critical time for both maternal and child healththe mortality rate is the highest among other developedhigh income countries and more than half of all maternal deaths occur postpartumfrom one day to one year after birthThis poor outcome is linked to the racial and ethnic disparities that disproportionately effect black women w ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Novel High-Resolution Scintillation X-ray Detectors for Digital Dentistry

    SBC: NGS Detectors LLC            Topic: NIDCR

    Project SummaryNovel High Resolution Scintillation X ray Detectors for Digital Dentistry The transition from traditional film to digital X ray detectors has resulted in significant improvements across many areas for dental X ray imaging ranging from decreased wait timesimproved logistics and even lower radiation dose ratesOne significant drawback remains with digital X ray imaging howeverwhich is ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. SBIR Phase I: Evaluating the feasibility of the TotalTHM-NOW for drinking water treatment plants to improve water quality, reduce costs, and lower cancer risks

    SBC: Foundation Instruments, Inc.            Topic: NIEHS

    PROJECT SUMMARY ABSTRACT Research has suggested that there is an increased risk of cancer associated with long term exposure to drinking water containing halogenated disinfection by productsDBPsTrihalomethanesTHMsare the most common class of halogenated DBPs formed during water chlorinationEvery yearthousands of drinking water treatment plantsWTPsstruggle with THMs compliance issues often allocati ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Fully Human Antibodies for the Prevention of Respiratory Syncytial Virus

    SBC: IDBiologics, Inc.            Topic: NIAID

    The goal of this STTR is to provide a preclinically validated monoclonal antibody or antibody combination for the prevention of respiratory syncytial virusRSVin high risk patients including infants and the elderlyWorldwideof children are infected with RSV before the age ofresulting in an estimatedmillion lower respiratory tract infectionsIn the United States adults overhavemillion RSV infections c ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a dual MDM2/XIAP inhibitor with a high therapeutic index for childhood cancers

    SBC: SEAK Therapeutics, LLC            Topic: 102

    PROJECT SUMMARYAcute lymphoblastic leukemiaALLand neuroblastomaNBare the most common cancers in childrenCurrently treatment options are often associated with severe side effectsThereforethere is a strong unmet medical need to develop targeted drugs with higher therapeutic indexes for improved treatment outcomeThe oncoproteins MDMand XIAP are important cell survival proteins in tumorsElevated MDMan ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Preventing Neurovascular Matrix Degradation and Hemorrhage in Acute Ischemic Stroke

    SBC: Translational Sciences Inc.            Topic: NHLBI

    Seventeen million people each year suffer from an ischemic stroke and millions are left dead and disabledTreatment with recombinant tissue plasminogen activatorr tPAis only modestly effective at reducing disability and it is associated with brain hemorrhage in up toof patients when serial imaging studies are performedBrain hemorrhage causes death and disability andis the major cause of early morta ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Multifunctional Semi-Powered Ankle Prosthesis: Phase II

    SBC: Synchro Motion LLC            Topic: NICHD

    PROJECT SUMMARY A conventional prosthetic ankle consists of a carbon fiber ankle foot complex that is nominally configured to a neutral positionThese prostheses generally work well for level walking and level ground standingbut lack the adaptability to explicitly accommodate other terrain or locomotion activitiessuch as slope walkingslope standingand stair ambulationAs suchcommon activities with a ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Long non-coding RNA signatures to track treatment responses in multiple sclerosis

    SBC: IQuity Labs, Inc.            Topic: NIAID

    ABSTRACTEarly detection of multiple sclerosis is key to limiting neurological damage but monitoring patient progression and response to therapy is of arguably similar if not greater importance due to the chronic nature of diseaseMoreoverrates of non adherence to therapy has been reported to be as high astoin the patient population suggesting the need to provide continuous monitoring and selection ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a lead cyclic-PDZ-Enhancer drug for Anxiety and Depression

    SBC: Aingeal, LLC            Topic: 101

    Major depressive disorder is a debilitating mood disorder that affectsof US adults in their lifetimecosting the U Seconomy more than $billion a yearDrugs that increase monoaminergic signaling are the mainstay of depression therapybut have a delayed onset of action and are only effective in aboutof affected patientsAberrant brain derived neurotrophic factorBDNFsignaling has been proposed to underli ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Autoscreen: An innovative e-health solution for early identification of Autism Spectrum Disorder Phase II

    SBC: Adaptive Technology Consulting, LLC            Topic: NIMH

    PROJECT SUMMARY Early accurate identification and treatment of young children with Autism Spectrum DisorderASDrepresents a pressing public health and clinical care challengeGiven mounting evidence that earlyaccurate diagnosis of ASD is possible and that very young children who receive intervention can demonstrate substantial gains in functioningcurrent American Academy of Pediatrics practice guide ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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