You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 7000 results
  1. Developing a novel system combining cognitive assessment with PASCALL FDA-cleared intraoperative anesthesia EEG brain monitor to prevent postoperative neurocognitive disorders in aging patients

    SBC: PASCALL Systems, Incorporated            Topic: NIA

    Each day, more than 100,000 patients undergo general anesthesia in the United States. The current practice of general anesthesia is prone to over-sedating patients, either due to the lack of brain monitoring or using brain monitors with inaccurate indices. Over-sedation (at 28% incidence) contributes to perioperative neurocognitive disorders (PNDs) in elderly population (≥65yrs). The cost of PND ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. The Commercialization of High-Resolution, Spinal Cord Stimulation for Non-Opioid Treatment of Neuropathic Pain

    SBC: MICRO-LEADS INC            Topic: NINDS

    Abstract DESCRIPTION. Our FastTrack SBIR proposal has developed HD64—a high-resolution, spinal cord stimulation therapy to provide more pain relief with greater specificity for those suffering from chronic neuropathic pain and opioid dependence. Over 25 million in the U.S. suffer from debilitating pain in the trunk and extremities and 55% depend on opioids to ease their suffering. Opioid abuse h ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Commercial Readiness in CTS Pain Management

    SBC: HIGHLAND INSTRUMENTS INC            Topic: NIAMS

    Proprietary: This proposal includes trade secrets and other proprietary or confidential information of Highland Instruments and is being provided for use by the National Institutes of Health (NIH) for the sole purpose of evaluating this SBIR proposal. No other rights are conferred. This proposal and the trade secrets and other proprietary or confidential information contained herein shall further ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Developing a selective TRPC3 ion channel inhibitor for epilepsy treatment

    SBC: SEAK Therapeutics, LLC            Topic: 106

    Project SummaryEpilepsy is one of the most common brain disorders. Current drugs have limited efficacy. Identifying new targeted drugs that can be used as safer, more effective therapies is in urgent unmet need. Selective inhibition of the transient receptor potential canonical 3 (TRPC3) emerges as a novel strategy to impede epilepsy. However, the currently best selective TRPC3 inhibitor, Pyr3, ha ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. A new process to improve the mechanical performance of crosslinked UHMWPE injoint replacement prostheses

    SBC: POLYMERIX TECHNOLOGIES LLC            Topic: NIAMS

    While total joint replacement prostheses have been a great success for over 80 years in providing mobility to patients with osteoarthritis, post-surgery complications like aseptic loosening, dislocation and infections remain as problems, often leading to costly and complicated revision surgery. The objective of this proposal is to address implant dislocation, the second most common complication fo ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. The Development of a Bimodal Walking-Running Prosthetic Foot

    SBC: LIBERATING TECHNOLOGIES INC            Topic: NICHD

    PROJECT SUMMARY / ABSTRACT Over the course of this two-year Phase II effort, Liberating Technologies, Inc. (LTI), along with its collaborators at Fillauer Companies and Hanger Clinic, will refine, expand, and test a bimodal walking-running foot that would then be poised to become a viable commercial product that can be reimbursed under the existing L-code reimbursement structure. The goal of this ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Unintrusive Pediatric Logging Orthotic Adherence Device: UPLOAD

    SBC: LIBERATING TECHNOLOGIES INC            Topic: NICHD

    PROJECT SUMMARY/ABSTRACT The application’s broad objective is to create a product that is able to improve remote compliance monitoring in pediatric orthotics applications by creating a device that combines all of the ideal compliance monitoring features into a single device called the Unintrusive Pediatric Logging Orthosis Analytic Device (UPLOAD). Our initial focus is on pediatric orthotic popu ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Inter-alpha Inhibitors in Experimental Necrotizing Enterocolitis

    SBC: PROTHERA BIOLOGICS, INC.            Topic: NICHD

    Necrotizing enterocolitis (NEC) is a devastating acute inflammatory condition of the gastrointestinal tract resulting in intestinal necrosis, systemic sepsis and multi-system organ failure found mostly in infants born prematurely. Despite modern medical advances in the past decade, the etiology remains elusive and morbidity and mortality are still unacceptably high. It has been concluded that the ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Optimizing Small Molecule Mechanomimetics to Treat Age-related Osteoporosis.

    SBC: OAK RIDGE THERAPEUTIC DISCOVERY LLC            Topic: NIA

    Abstract There is an unmet need to develop treatments for senile osteoporosis, a disorder characterized by an age-related reciprocal decrease in osteogenesis and increase in bone marrow fat. Senile osteoporosis resembles disuse osteopenia, suggesting its pathogenesis involves impaired bone mechanosensing. We discovered that the polycystin heterotrimeric complex (1PC1+3PC2) functions as a mechanose ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Commercialization of an Improved Treatment of Extremity Fractures Using a Regenerative Bone Adhesive to Accelerate Bone Healing in Aging Patients

    SBC: REVBIO, INC.            Topic: NIA

    Project Abstract/Summary In the U.S., about 2.1 million people experience a fragility fracture each year. This number is expected to double or triple by 2040 as the population ages. Injuries in the upper and lower extremities equate to more than 40% of fragility fractures, and experiencing a prior fracture is associated with an 86% increased risk of recurrence. Falls from standing height and other ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government