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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 7937 results
  1. Extended half-life GlyTR1 combined with checkpoint blockade for Cancer Immunotherapy

    SBC: GLYTR THERAPEUTICS, INC.            Topic: 102

    AbstractTreatment of non-resectable recurrent/metastatic solid cancers is currently palliative only and there is an urgent unmet need for novel mechanisms of action and additional paradigm shifting therapeutic options. Antigen- targeting cancer immunotherapies such as bi-specific antibodies (eg Bi-specific T cell engager or BiTE’s) provide a unique approach for cancer immunotherapy. However, app ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Point of Care HPV 16/18/45 DNA Test for Cervical Cancer

    SBC: CROSSLIFE TECHNOLOGIES INC.            Topic: 102

    Point of Care HPV 16/18/45 DNA Test for Cervical Cancer. CrossLife Technologies Inc. Project Summary/Abstract Human cervical cancer is the fourth most common cancer among women worldwide [1]. Despite cervical cancer has been thoroughly studied and the mortality has been significantly reduced through efficient screening, these preventive programs are found to be less effective in developing countri ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. P-FITS: The Pediatric Food Intake Technology System

    SBC: Viocare, Inc.            Topic: NICHD

    Diet plays an integral role in the physical, emotional, and general health of children and adolescents. The consequences of poor diet during this critical time period are long-lasting, with nutritional status being a strong risk factor for chronic conditions throughout adolescence and adulthood. Current dietary assessment tools available for self-administration in older children are extremely limi ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Quantifying microstructural changes in Alzheimer's disease using Restriction Spectrum Imaging

    SBC: Cortechs Labs, Inc.            Topic: NIA

    Project Summary/Abstract The overall goal of this project is to deliver an automated diffusion image analysis tool to be used in a clinical setting that quickly evaluates the diffusion images in conjunction with MR volumetric images and reports diffusion-based microstructural parameters derived from segmented anatomical locations to determine Alzheimer’s disease status of patients. Alzheimer’s ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Quantitative Modeling Software with Applications to Medical Decision Making

    SBC: Berkeley Madonna, Inc.            Topic: NLM

    Project Summary/Abstract In recent years, health care systems and physicians have made concerted efforts to practice evidence-based medicine and provide patients with the best available information when making choices about their medical care. However, medical decisions are often complex with many uncertainties and potential outcomes to consider, some beneficial and some adverse. A popular analyti ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Next generation MEMS-VCSEL technology for ultra-low-cost dental and periodontal swept source optical coherence tomography imaging

    SBC: PRAEVIUM RESEARCH INC            Topic: NIDCR

    This proposal aims to enable a new generation of high-speed, low-cost, wavelength-flexible swept source optical coherence tomography (SS-OCT) imaging device technology targeting applications in dental imaging and based on microelectromechanical systems vertical cavity surface emitting lasers (MEMS-VCSELs) and planar lightwave circuits (PLCs). MEMS-VCSELs provide an unmatched combination of high an ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Leveraging remote blood pressure monitoring and interpretable machine learning to improve clinical workflows for hypertensive disorders of pregnancy

    SBC: DELFINA CARE INC.            Topic: NICHD

    Project Summary/Abstract: Hypertensive disorders of pregnancy (HDP) are a leading cause of pregnancy-related deaths in the United States. Specific interventions, such as nutrition counseling and prophylactic aspirin use, are known to prevent the onset and exacerbation of HDP. However, current approaches to identify patients early in pregnancy are limited due to challenges collating patient data fr ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. A point of care-device for the determination of creatinine phosphokinase (CPK), the CPK Now

    SBC: ANALYTICAL DIAGNOSTIC SOLUTIONS INC            Topic: NICHD

    AbstractThis application is in regard to the National Center for Advancing Translational Sciences SBIR/STTR Omnibus Solicitation. In Vitro Diagnostic Solutions, LLC (IVDS) proposes to develop a point-of-care test (POCT) to rapidly determine blood creatine phosphokinase (CPK) activity for the improved management of long-chain fatty acid oxidation disorders (LCFAODs). FAODs are inborn errors of meta ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Developing a selective TRPC3 ion channel inhibitor for epilepsy treatment

    SBC: SEAK Therapeutics, LLC            Topic: 106

    Project SummaryEpilepsy is one of the most common brain disorders. Current drugs have limited efficacy. Identifying new targeted drugs that can be used as safer, more effective therapies is in urgent unmet need. Selective inhibition of the transient receptor potential canonical 3 (TRPC3) emerges as a novel strategy to impede epilepsy. However, the currently best selective TRPC3 inhibitor, Pyr3, ha ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Advancing precision pain medicines to the clinic

    SBC: NAVEGA THERAPEUTICS, INC.            Topic: 104

    Abstract Chronic pain is pain that persists past the normal time of healing. 1.5 billion people worldwide suffer from chronic pain and this number continues to increase as the elderly population grows, the prevalence of diabetes rises, and cancer survival rates improve. Chronic pain not only severely impacts daily quality of life for many patients, it also places a heavy socioeconomic burden on so ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
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