Award Data

DESCRIPTION provided by applicant The past decade has seen a rapid increase in the application of brain stimulation devices to treat a variety of movement disorders such as Parkinsonandapos s disease PD and other neuropathologies Present noninvasive brain stimulation technologies suffer from fundamental limitations and have yet to reach the level of efficacy of invasive methods such as de ...

DESCRIPTION provided by applicant Errors in the administration of medications to residents of long term care facilities LTCFs threaten resident safety and add significant unnecessary costs to the healthcare system Use of unit dose medications that require LTCF staff to manually sort and assemble specific patient medications times per day can result in error rates as high as with of total errors ha ...

DESCRIPTION provided by applicant Optogenetic tools for activating and silencing specific neurons embedded within dense brain networks in a temporally precise fashion using light are key to understanding the roles that specific neurons play in behavior neural computation and disease In our Phase I SBIR Ferro Solutions and the Boyden lab at MIT collaborated to develop a fully wirelessly powered and ...

DESCRIPTION provided by applicant Evaluation of dental tobacco cessation tool in practice based research network This Phase II project will finish development and evaluate QuitAdvisorDDS as a tool for dental providers to advise patients on tobacco cessation The University of Kentucky will evaluate the effectiveness of QuitAdvisorDDS in increasing quit attempts in tobacco using patients The ev ...

DESCRIPTION Undesired platelet activation can be result of many common pathologies or interventions Arterial thrombosis and the acute ischemic events that follow such as myocardial infarction and stroke are among the leading causes of death incapacitation and rising health care costs in the developed world Therefore antiplatelet drugs have significant market share and clinical importance ...

DESCRIPTION provided by applicant This application andquot Imaging Software of Functional Connectivity MRI for Alzheimerandapos s Diseaseandquot is written in response to PA andquot Lab to Marketplace Tools for Brain and Behavioral Research SBIR R R andquot Alzheimerandapos s disease AD is the most common form of dementia However developing drugs that effectively slow or alter the course of Alzhei ...

DESCRIPTION provided by applicant The goal of this project is to develop a therapeutic acting specifically against Helicobacter pylori the causative agent of peptic ulcer and gastric carcinoma Roughly every other person carries the pathogen and there are an estimated cases annually of active infection in the US The currently used triple therapy is a combination of a proton pump inhibitor and broad ...

DESCRIPTION provided by applicant My Coverage Plan Inc MCP proposes to use our newly patented technology to create a commercially viable and nationally replicable suite of software and services for health care providers and other social service agencies that reduces avoidable health disparities and increases provider reimbursements The MCP health IT solution will help providers proactively ...

DESCRIPTION provided by applicant Medication safety is an important concern in hospital Emergency Departments EDs which provide approximately million patient visits annually in the US and are a common site of care for health disparity populations In more than one third of ED visits patients are unable to provide an accurate list of their medications Discrepancies and other errors in ...

DESCRIPTION provided by applicant The overall goal of this project is to discover novel antibiotics to combat important drug resistant pathogens We are running out of treatment options for pathogens such as S aureus MRSA vancomycin resistant Enterococci VRE multidrug resistant P aeruginosa A baumannii ESBL and New Delhi metallo b lactamase producing Enterobacteriaceae and M tuberculosis Only novel ...