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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Risperidone Subcutaneous Implant

    SBC: Delpor, Inc            Topic: 101

    DESCRIPTION provided by applicant The objective of the proposed study is to develop a subcutaneous implant of risperidone which provides consistent therapeutic blood levels of the drug for months The benefits of such product include improved medication adherence the ability to withdraw the medication if needed due to treatment emergent Adverse Effects AEs fewer relapses and improved eff ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Commercialization of a Benchtop Radiosynthesizer for the Production of PET Probes

    SBC: Sofie Biosciences, Inc.            Topic: NIMH

    DESCRIPTION provided by applicant Positron Emission Tomography PET is a molecular imaging modality that utilizes radiolabeled molecules andquot probesandquot to target and measure biological processes Basic scientists can use the same probes to examine cells and mice as they do in patients to visualize and characterize the biology of disease monitor its progression and evaluate therapeutic efficac ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Diametrically Patterned Dural Graft for Enhanced Dura Mater Regeneration

    SBC: NANONERVE, INC.            Topic: NINDS

    DESCRIPTION provided by applicant NanoNerve is developing a novel diametrically patterned nanofibrous dural substitute for rapid dura mater regeneration following neurosurgical procedures In the US alone neurosurgical procedures are performed annually that require patching of the dura mater to prevent leakage infection and neural damage Currently available dural substitutes include xenogenic colla ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Novel, Chronic, Volume Microelectrodes for the Broad Neuroscience Community

    SBC: Modular Bionics Inc            Topic: 102

    DESCRIPTION provided by applicant Novel Chronic Volume Microelectrodes for the Broad Neuroscience Community Project Summary Neuroscience researchers studying the nervous system have relied on microelectrode devices to record neural activity for decades Microelectrodes are micro scale structures with exposed conductive regions that are inserted within nervous systems to record the activity of ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. NeuroPlay Adventures for K-2

    SBC: MORPHONIX            Topic: NIMH

    DESCRIPTION provided by applicant NeuroPlay Adventures addresses the need to develop innovative neuroscience educational tools to benefit children in kindergarten through th grade K The goals of this project are to develop mobile apps for tablets and smart phones and a web site that introduces children ages to the brain using music motor and story based activities and to evaluate the effectiveness ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Non-invasive Blood Alcohol Sensor for Emergency Room Applications

    SBC: Intelligent Optical Systems, Inc.            Topic: 150

    DESCRIPTION provided by applicant Project Summary Accurate quantification of alcohol and drugs of abuse intoxication in emergency rooms ERs is an important screening step for a precise diagnosis and hence for prompt treatment Some severe emergencies such as traumatic head injury diabetes and stroke can be misdiagnosed in the absence of screening for alcohol and drug intoxication reliable ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Biocomputation across distributed private datasets to enhance drug discovery

    SBC: COLLABORATIVE DRUG DISCOVERY, INC.            Topic: NCATS

    DESCRIPTION Collaborative Drug Discovery Inc CDD will create a novel web based software platform that enables scientists to work together effectively to discover and improve new drug leads by sharing computational predictions based on open source descriptors and models for the first time without needing to reveal underlying chemical structures and biodata It will create the first practical system ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. MRI-Compatible Fiber-Optically Sensorized Biopsy Needles for Oncological Applicat

    SBC: Intelligent Fiber Optic Systems Corporation            Topic: NIBIB

    DESCRIPTION provided by applicant The goal of this research is to develop an innovative prototypical medical device treatment system capable of detecting and visualizing three dimensional shape and tip position of a biopsy needle during Magnetic Resonance Imaging MRI or other image assisted interventional radiological procedures This work will be done in collaboration with interventional rad ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Cell Lysates to Sequencing Reads: A Multiplex Gene Expression Profiling Tool for

    SBC: BioSpyder Technologies, Inc.            Topic: 172

    DESCRIPTION provided by applicant This proposed Phase I SBIR project will transfer RASL Seq a targeted sequencing technology developed in academia to a small business Xpress Inc and demonstrate feasibility for its commercialization as a platform for drug discovery and high throughput screening HTS The technology detects hundreds of RNA targets at once in cell lysates using oligo li ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Safety of Allogeneic Cardiosphere-Derived Cells for Dilated Cardiomyopathy

    SBC: CAPRICOR, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant Project Abstract Capricor Inc has an allogeneic cell therapy product CAP presently in clinical development CAP consists of cardiosphere derived cells CDCs grown from a donor unrelated to the recipient using a proprietary process exclusively licensed to Capricor Autologous CDCs have demonstrated their utility as a regenerative agent able to ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
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