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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Assistive Device to Improve Object Recognition and Reading

    SBC: Aeon Imaging, LLC            Topic: na

    The goal of this project is to create an affordable system for optimizing the use of assistive devices (tablets) to improve reading and object recognition performance for individuals with visual impairments. The objectives are: (1) to select a suitable assistive device that can be paired with Aeon’s existing Digital Light Ophthalmoscope (DLO-LV) vision research retinal camera which maps the posi ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. Confocal and Autofluorescence Imaging of Macular Degeneration using a Low Cost Digital Imager

    SBC: Aeon Imaging, LLC            Topic: W

    Project SummaryAbstract The overall goal of the proposed SBIR Phase II research is to build and evaluate a low costmulti mode retinal camera used to detect and manage causes of macular impairmentAge related macular degenerationAMDremains the most common cause of permanent vision loss in the US and many industrialized countriesTreatments with portable lasers and injectable drugs can save sightbut e ...

    SBIR Phase II 2018 Department of Health and Human Services
  3. Polymeric nanoparticles for inductive browning of white adipose tissue

    SBC: ADIPO THERAPEUTICS, LLC            Topic: 200

    Global epidemics of obesity and its associated comorbidities pose formidable challenges to human healthCurrent few medications available for obesity treatment only produce modest effects and are usually accompanied with unpleasantpotentially harmful side effectsThere is accumulating evidence that significant metabolic differences that distinguish beige brown adipocytes from white adipocytes can po ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. Stage-Based Mobile Intervention for Substance Use Disorders in Primary Care: Implementation and Cluster-Randomized Trial

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    Nearlymillion Americans ageand olderneed treatment for a substance use disorderSUDWhile onlyof individuals requiring treatment for a SUD receive itan estimated two thirds see a primary care or urgent care provider everymonthsPrimary care providers are in a unique position to perform ScreeningBrief Interventionand Referral to TreatmentSBIRTWith Phase I contract fundingPro Change developed and pilot ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. A cost-effective robotic platform for on-demand production of flexibly dosed medications in a chewable gummy dosage form

    SBC: Vitae Industries, Inc.            Topic: NICHD

    PROJECT SUMMARYThis project s goal is to develop an innovative cost effective robotic platform for fast on demand pharmacy production of pediatric drugs as individually tailored palatable gummy dosage formsMedication adherence is notoriously low among children due to difficulty swallowing pills and rejection of bad tasting medicationsAlthough some common pediatric drugs have flavored liquid formsp ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Development of novel small molecule analgesics modulating the nNOS-NOS1AP protein-protein interaction

    SBC: ANAGIN            Topic: 103

    Abstract This applicationDevelopment of novel small molecule analgesics modulating the nNOS NOS AP proteinprotein interactionaddresses the critical need for more effective medications to treat chronic neuropathic pain affectingmillion people in the United StatesCurrent pain medications such as NSAIDSsteroidsopiates and gabapentin analogs have documented and often severe side effectsare poorly effe ...

    SBIR Phase II 2018 Department of Health and Human Services
  7. Caring for the Caregiver: A Theory-Driven Mobile Intervention to Promote Caregiver Well-Being

    SBC: Pro-Change Behavior Systems Inc            Topic: NIA

    Overmillion Americans are currently providing unpaid care to a family memberrelativeor friend with Alzheimer s disease or related dementiaWhile caregiving can be a positive experience that brings meaning and an increased sense of purposeit can also take a tollNearlyof Alzheimer s and dementia caregivers rate their emotional distress as high or very highand as many assuffer from depressionCaregiver ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Development and feasibility of prevention-minded oral health mobile App based on dietary selections and oral hygiene events.

    SBC: Indiana Nanotech, LLC            Topic: NIDCR

    The number of decayed and filled tooth surfaces in primary dentition is on the rise in US children between the ages ofandyears oldin factof adolescentsbetweenandyears oldandout ofdentate seniorsagebear evidence of dental cariesReinforced with areport statingof those between the ages ofandhave dental cariesvirtually all walks of life are thus affectedand this doesn t even include those unreportedor ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Fluoroscopic drill attachment for orthopedic trauma surgery

    SBC: Eclipse Orthopaedics, LLC            Topic: NIAMS

    Abstract Aboutleg and hip fractures each year are treated by implanting a stiff metal rod or intramedullaryIMnailthrough the center of the bone and fixing the ends of the nail to the bone with screwsBut placing the locking screws to fix the rod to the bone is difficultTo anchor the nail securelythe surgeon must accurately drill pilot holes through both the bone and locking holes in the nailwhile t ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. Targeting Therapeutics for Accelerated Bone Fracture Repair

    SBC: Novosteo Inc.            Topic: NIDCR

    Project Summary Abstract SignificanceThe failure of bone fractures to adequately repair in elderly patients causes significant morbidity and mortality each year in the United StatesThis problem will continue to be exacerbated by an aging populationwith aincrease in hip fractures alone expected byand significant costs in lost workquality of lifephysical therapyextended care facility staysand surger ...

    SBIR Phase I 2018 Department of Health and Human Services

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