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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Mobile multifunctional tool for monitoring and management of respiratory diseases

    SBC: TF HEALTH CORPORATION            Topic: NHLBI

    DESCRIPTION provided by applicant Mobile multifunctional tool for monitoring and management of respiratory diseases Chronic Obstructive Pulmonary Disease COPD and asthma affect millions of people worldwide Because there is no permanent cure for these diseases efficient management of the patients is needed New mobile health technologies such as personal devices that allow patients to monit ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a prototype system for assaying exocytosis from individual cells using using transparent microelectrode arrays

    SBC: EXOCYTRONICS, LLC            Topic: 101

    DESCRIPTION provided by applicant Cells secrete hormones and neurotransmitter via exocytosis Understanding how exocytosis is regulated and how pharmaceuticals and toxins inhibit exocytosis is of broad medical significance because it aids in developing approaches to treat medical conditions where release of transmitter needs to be enhanced e g Parkinsonandapos s disease or inhibited e g ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Rapid Magnetomotive Thrombolysis for Stroke

    SBC: Pulse Therapeutics, Inc.            Topic: 105

    DESCRIPTION provided by applicant Acute ischemic stroke AIS is the result of a blood clot in a cerebral artery It remains a leading killer and the leading cause of long term disabilit annually impacting over Americans Because brain tissue rapidly dies time to reperfusion is critical in both preventing death and improving neurological outcomes While current annual costs relat ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Rational design of small interfering RNA for genome-wide target knockdown

    SBC: Nawgen, LLC            Topic: 172

    DESCRIPTION provided by applicant RNA interference RNAi is a small RNA guided gene silencing process within living cells The RNAi technique is widely used in both biological research and clinical applications because it has the ability to knockdown essentially any gene of interest However one major unresolved issue in RNAi studies is non specific gene silencing It is well known that in ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Improving Interlock Compliance with Computerized Education and Monitoring Systems

    SBC: AXXESS UNLIMITED, LLC            Topic: 400

    DESCRIPTION provided by applicant All States have enacted laws providing for alcohol ignition interlocks as a sanction for impaired driving Going forward interlock programs may become as widely used with impaired drivers as license suspension even though they are more time consuming and expensive for the government to manage Although the extra expense of managing interlock programs is jus ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Recruiting underserved populations into clinical trials with customizable media

    SBC: Health Communication Impact, LLC            Topic: 100

    DESCRIPTION provided by applicant Racial and ethnic minorities older adults and those from rural communities continue to be underrepresented in cancer and other clinical trials research despite annual spending on patient recruitment in excess of $ billion While many individual studies have demonstrated that targeted outreach and education to underrepresented patients and engagement of fro ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Electrochemically Enhanced Plasmonic Imaging for Quantitative Proteomics

    SBC: BIOSENSING INSTRUMENT INC            Topic: 400

    DESCRIPTION provided by applicant We are proposing a technology to help in three key areas of proteomics including a recognition of protein interactions b characterization of post translational modifications and c quantitative measurements at high spatial and or temporal resolution to address the dynamics of protein interactions Several significant types of protein interactions remain ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Reduced gluten cereal grains

    SBC: Arcadia Biosciences, Inc.            Topic: 300

    DESCRIPTION provided by applicant Celiac disease CD is the most common food sensitive enteropathy known affecting approximately of the population and its incidence appears to be on the rise In addition non celiac gluten sensitivity GS has recently been revealed to be a distinct condition that affects a growing number of individuals Both of these conditions are triggered by gluten a ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. A NOVEL TARGETED DELIVERY SYSTEM FOR CANCER TREATMENT AND DIAGNOSIS

    SBC: ENDURX PHARMACEUTICALS INC            Topic: 102

    DESCRIPTION provided by applicant Glioblastoma multiforme GBM or andquot glioblastoma andquot is the most common and aggressive malignant primary brain tumor in humans An effective treatment that increases patient survival would represent a significant advance in the field and provide a desperately needed new therapy for this deadly disease EnduRx is focused on the development of new tar ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a standardized kit for the isolation, enrichment, and high-sensitivity profiling of circular RNAs in the nervous system

    SBC: COFACTOR GENOMICS, INC.            Topic: NIDA

    DESCRIPTION provided by applicant Long term objectives Modified ribonucleic acids RNA are important regulators of numerous cellular processes and are increasingly being associated with human diseases For example non coding microRNAs play significant roles in neuronal development and can serve as biomarkers for psychiatric disorders Another such modified RNA is circular RNA circRNA a ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
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