List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. FOR AGRICULTURE AND RANGE

    SBC: Earth Satellite Corpon            Topic: N/A

    NOAA AVHRR DATA HAS PROVIDED USEFUL QUALITATIVE INFORMATION IN AGRICULTURE AND FORESTRY APPLICATIONS. QUANTITATIVE APPLICATIONS OF AVHRR ARE HOWEVER IN THEIR INFANCY. STUDIES BY EARTHSAT PERSONNEL HAVE SHOWN THAT FOR ONE YEAR IN ONE LOCATION CORN YIELD CAN BE QUANTITATIVELY RELATED TO AVHRR VEGETATION INDEX COUNT VALUES. THE PROPOSED STUDIES WILL EXAMINE FURTHER QUANTITATIVE APPLICATIONS OF AVHRR ...

    SBIR Phase I 1985 Department of Commerce
  2. THE GOAL OF THIS PROJECT WILL BE TO SCREEN NEW DERIVATIVES OF L-ASCORBIC ACID ADDUCTS CLASSIFIED AS METHYLFURYLBUTYROLACTONES, ALSO REFERRED TO AS NAFOCARE B.

    SBC: American Biotechnology Co            Topic: N/A

    THE GOAL OF THIS PROJECT WILL BE TO SCREEN NEW DERIVATIVES OF L-ASCORBIC ACID ADDUCTS CLASSIFIED AS METHYLFURYLBUTYROLACTONES, ALSO REFERRED TO AS NAFOCARE B. WORKING IN COLLABORATION WITH A SYNTHETIC ORGANIC CHEMISTRY GROUP AT WEST VIRGINIA UNIVERSITY, WE HAVE DETERMINED THAT THE PARENT COMPOUND, MFBL, HAS EXTENSIVE IMMUNE POTENTIATING ACTIVITY. OUR PROJECT WILL ANALYZE FIVE NEW DERIVATIVES OF L- ...

    SBIR Phase I 1985 Department of Health and Human Services
  3. AND ITS POTENTIAL APPLICATION TO HUMAN HYBRIDOMA TECHNOLOGY.

    SBC: American Biotechnology Co            Topic: N/A

    AND ITS POTENTIAL APPLICATION TO HUMAN HYBRIDOMA TECHNOLOGY.THIS PROJECT INVOLVES DETERMINING THE ABILITY OF A NEW CLASS OF SYNTHETIC BIOLOGICAL RESPONSE MODIFIERS (BRM) KNOWN AS METHYLFURYLBUTYROLACTONES (MFBL) TO AUGMENT THE PRODUCTION OF LYMPHOKINES (IL-2, B-CELL GROWTH FACTOR, AND IMMUNE INTERFERON) AND MONOKINES (IL-1, PROSTAGLANDINS, AND CYTOLYTIC FACTOR). OUR LABORATORY HAS DETERMINED THAT ...

    SBIR Phase I 1985 Department of Health and Human Services
  4. ALTHOUGH INVESTIGATION INTO BIOLOGICAL RESPONSE MODIFIERS HAS INCREASED RECENTLY, MOST OF THE EFFORT HAS BEEN TOWARDS POTENTIATING THE HOST'S CELL-MEDIATED IMMUNITY.

    SBC: American Biotechnology Co            Topic: N/A

    ALTHOUGH INVESTIGATION INTO BIOLOGICAL RESPONSE MODIFIERS HAS INCREASED RECENTLY, MOST OF THE EFFORT HAS BEEN TOWARDS POTENTIATING THE HOST'S CELL-MEDIATED IMMUNITY. DATA ACCUMULATED BY OUR LABORATORIES INDICATE THAT THE METHYLFURYLBUTYROLACTONE (MFBL) CLASS OF COMPOUNDS REPRESENTS NEW SYNTHETIC IMMUNE RESPONSE MODIFIERS CAPABLE OF ACTIVATING SEVERAL COMPONENTS OF IMMUNE RESPONSE WITH NEGLIGIBLE T ...

    SBIR Phase I 1985 Department of Health and Human Services
  5. STABLE ANTITUMOR PLATINUM COMPLEXES

    SBC: AMT, INC.            Topic: N/A

    THE OBJECTIVE OF THIS STUDY IS TO PREPARE ANTINEOPLASTIC PLATINUM COMPLEXES WITH STABILITIES IN SOLUTION GREATER THANTHAT OF 4-CARBOXYPHTHALATO(1,2-DIAMINOCYCLOHEXANE) PLATINUM (NSC 271674;DACHPT). NSC 271674 IS A CISPLATIN ANALOG INVENTED BY THE APPLICANT AND NOW IN PHASE II CLINICAL TRIALS AT MEMORIAL SLOAN-KETTERING CANCER CENTER IN NEW YORK. IT IS ACTIVE AGAINST CISPLATIN-RESISTANT TUMORS WITH ...

    SBIR Phase II 1985 Department of Health and Human Services
  6. THE PROVEN CLINICAL EFFECTIVENESS OF CISPLATIN AS WELL AS SEVERAL SECOND GENERATION ANALOGS HAS ESTABLISHED THE ROLE OF METAL COORDINATION COMPOUNDS IN CANCER CHEMOTHERAPY.

    SBC: AMT, INC.            Topic: N/A

    THE PROVEN CLINICAL EFFECTIVENESS OF CISPLATIN AS WELL AS SEVERAL SECOND GENERATION ANALOGS HAS ESTABLISHED THE ROLE OF METAL COORDINATION COMPOUNDS IN CANCER CHEMOTHERAPY. COMPLEXES OF METALS OTHER THAN PLATINUM HAVE BEEN OFTEN POORLY DESIGNED BECAUSE THEY WERE MODELED AFTER THE ACTIVE PLATINUM COMPLEXES WITHOUT CONSIDERING THEIR DIFFERENT THERMODYNAMIC AND KINETIC PARAMETERS. IN PARTICULAR, PALL ...

    SBIR Phase I 1985 Department of Health and Human Services
  7. THE OBJECTIVE OF THIS STUDY IS TO SYNTHESIZE, CHARACTERIZE, AND EVALUATE BIOLOGICAL PROPERTIES OF POLYMERIC PLATINUM COMPLEXES IN AN EFFORT TO ENHANCE SOLUBILITY AND STABILITY WHILE REDUCING TOXICITY AND OBTAINING GREATER SUSTAINED ACTIVITY THAN THAT

    SBC: AMT, INC.            Topic: N/A

    THE OBJECTIVE OF THIS STUDY IS TO SYNTHESIZE, CHARACTERIZE, AND EVALUATE BIOLOGICAL PROPERTIES OF POLYMERIC PLATINUM COMPLEXES IN AN EFFORT TO ENHANCE SOLUBILITY AND STABILITY WHILE REDUCING TOXICITY AND OBTAINING GREATER SUSTAINED ACTIVITY THAN THAT FOUND WITH ACTIVE, STRUCTURALLY RELATED, MONOMERIC COMPLEXES. THE PHASE I RESEARCH PLAN IS BASED ON THE PROMISING PRELIMINARY IN VIVO RESULTS OBTAINE ...

    SBIR Phase I 1985 Department of Health and Human Services
  8. THIS PROJECT AIMS TO DEVELOP A MICROCOMPUTER DATABASE MANAGEMENT AND TESTING SYSTEM FOR CHILDHOOD PSYCHOPHARMACOLOGY AND CHILD PSYCHIATRY, WITH A FULLY DOCUMENTED, SELF-INSTRUCTIONAL, ON-SITE SYSTEM WHICH WILL ALLOW CLINICIANS AND INVESTIGATORS TO TEST,

    SBC: Behavioral Medicine, Inc.            Topic: N/A

    THIS PROJECT AIMS TO DEVELOP A MICROCOMPUTER DATABASE MANAGEMENT AND TESTING SYSTEM FOR CHILDHOOD PSYCHOPHARMACOLOGY AND CHILD PSYCHIATRY, WITH A FULLY DOCUMENTED, SELF-INSTRUCTIONAL, ON-SITE SYSTEM WHICH WILL ALLOW CLINICIANS AND INVESTIGATORS TO TEST, RECORD, AND SUMMARIZE PATIENT DATA SUITABLE FOR CLINICAL DRUG TRIALS AND OTHER CLINICAL PSYCHIATRIC APPLICATIONS. A COMPLETE SET OF RATING SCALES, ...

    SBIR Phase I 1985 Department of Health and Human Services
  9. THE LONG-TERM OBJECTIVE OF THIS PROJECT IS TO ESTABLISH A STABLE SOURCE OF WELL-CHARACTERIZED ANTIBODIES TO DNA ADDUCTS OF CARCINOGENS/MUTAGENS, SO THAT THESE IMPORTANT PROBES CAN BE MADE AVAILABLE FOR RESEARCH INTO MECHANISM(S) OF CARCINOGENESIS, AND

    SBC: Biological Research Faculty &            Topic: N/A

    THE LONG-TERM OBJECTIVE OF THIS PROJECT IS TO ESTABLISH A STABLE SOURCE OF WELL-CHARACTERIZED ANTIBODIES TO DNA ADDUCTS OF CARCINOGENS/MUTAGENS, SO THAT THESE IMPORTANT PROBES CAN BE MADE AVAILABLE FOR RESEARCH INTO MECHANISM(S) OF CARCINOGENESIS, AND FOR MOLECULAR CANCER EPIDEMIOLOGY TO MONITOR HUMAN POPULATIONS FOR POSSIBLE EXPOSURE TO ENVIRONMENTAL CARCINOGENS. PHASE I EFFORTS INVOLVE: A.PRODUC ...

    SBIR Phase I 1985 Department of Health and Human Services
  10. THE OBJECTIVE OF THIS PROJECT IS TO ESTABLISH INNOVATIVE SCREENING SYSTEMS THAT IDENTIFY NEW CHEMOPREVENTIVE AGENTS, USING DIFFERENT IN VITRO MODELS OF ONCOGENESIS.

    SBC: Biological Research Faculty &            Topic: N/A

    THE OBJECTIVE OF THIS PROJECT IS TO ESTABLISH INNOVATIVE SCREENING SYSTEMS THAT IDENTIFY NEW CHEMOPREVENTIVE AGENTS, USING DIFFERENT IN VITRO MODELS OF ONCOGENESIS. THREE POTENTIAL SYSTEMS, EACH REPRESENTING A DIFFERENT STAGE IN THE CARCINOGENIC PROCESS, WILL BE TESTED AGAINST SELECTED CHEMOPREVENTIVE AGENTS. PHASE I EFFORTS INVOLVE DETERMINATION OF THE INHIBITORY EFFECTS OF RETINOIDS ON: A.IMMORT ...

    SBIR Phase I 1985 Department of Health and Human Services

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government