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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. CLASP Phase II: producing a Coastal Long-Term Automated Self-Calibrating Profiler Commercial Prototype

    SBC: Green Eyes, LLC            Topic: 814

    In our Phase I test, Green Eyes successfully demonstrated the feasibility of a Coastal Long-Term Automated Self-Calibrating Profiler (CLASP) system capable of autonomous operation for one year. The feasibility prototype also incorporated two-way telemetry and near real-time display of processed data. CLASP uses a profiling pump to deliver water to a flow-through multi probe sensor and additional ...

    SBIR Phase II 2008 Department of Commerce
  2. Carbon Nanotube Methods for Molecular Identification of Fish Species

    SBC: Pettit Applied Technologies, Inc.            Topic: 817

    Identification of particular fish species based on specific DNA sequences is not currently time or cost effective, but morphological identification is not always possible during early development stages. The project proposed seeks to develop a microfluidic based approach using DNA hybridization, coupled with a sensitive detection method based on the use of carbon nanotubes to rapidly identify fis ...

    SBIR Phase I 2008 Department of Commerce
  3. Dredged Channel Depth Monitoring

    SBC: SURVICE ENGINEERING COMPANY, LLC, THE            Topic: 844

    The condition of dredged channels in U.S. waterways is ever-changing due to sedimentation, shoaling, and the growing presence of submerged debris. Furthermore, the lack of the most current and accurate subsurface terrain data (specifically, channel depth as a function of position) at the time of a ship¿s transit introduces a level of uncertainty that prevents optimal safety and navigational ef ...

    SBIR Phase I 2008 Department of Commerce
  4. Inhaled nisin as an emergency intervention against antibiotic sensitive or resist

    SBC: AFG BIOSOLUTIONS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The deliberate release of Bacillus anthracis spores remains an imminent threat both in terms of bioterrorism and biowarfare. Individuals who inhale these spores are at extreme risk of infection and death from anthrax. C urrent prophylaxis and therapy in the event of B. anthracis spore inhalation fall into two categories. Vaccination to protect against future ex ...

    SBIR Phase I 2008 Department of Health and Human Services
  5. Add-on module for ONCAD for diagnosing infiltrating lobular carcinoma

    SBC: Alan Penn & Associates Inc            Topic: N/A

    DESCRIPTION (provided by applicant): The specific aim of this study is to develop an add-on module for the ONCAD breast MRI CAD system that will provide radiologists with additional assistance when they have suspicion of the presence of infiltrating lobula r carcinoma (ILC). The proposed research will investigate the possibility of developing, training and evaluating an ILC- specific algorithm tha ...

    SBIR Phase I 2008 Department of Health and Human Services
  6. Generation of a Modified DT_IL3 Fusion Toxin

    SBC: ANJIN GROUP, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A number of protein fusion toxins, composed of the diphtheria toxin (DT) toxophore and a targeting ligand, have been assembled and tested in Phase I clinical trials for the treatment of leukemias. To date, the only FDA approved protein fusion toxin is ONTAK. ONTAK is a DT, interleukin-2 receptor-targeted fusion toxin used to treat persistent or recurrent, cuta ...

    SBIR Phase I 2008 Department of Health and Human Services
  7. Further Analysis of a VLS Modified IL-2 Receptor Targeted Toxin

    SBC: ANJIN GROUP, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The project seeks to further the development of a series of diphtheria toxin mutants which, when employed in the construction of protein fusion toxins, display reduced induction of leakage through vascular endothelial c ell monolayers. The goals of this Phase I proposal are to evaluate two, in vivo models of vascular leakage, selecting one model for further in ...

    SBIR Phase I 2008 Department of Health and Human Services
  8. In vivo RNAi nanoparticle cancer gene function reagent

    SBC: APARNA BIOSCIENCES CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): In spite of recent advances, cancer remains a major killer posing a dire need for more effective therapy, and unfortunately this is particularly true for metastatic non-small cell lung cancer (NSCLC), which afflicts an extremely large number of patients and is one of the least treatable cancers. With the growing success of targeted therapeutics, it has become ...

    SBIR Phase I 2008 Department of Health and Human Services
  9. Hybrid synthetic targeted lenti-VLP nanoparticle for gene delivery

    SBC: APARNA BIOSCIENCES CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): A need for better gene delivery has blocked the potential advancement in biomedical research and most critically development of better therapeutics that operate at the gene function level. This problem is most acute for non-dividing cells, which in fact are the predominant cell type. Thus the considerable interest in gene therapy has narrowed considerably to e ...

    SBIR Phase I 2008 Department of Health and Human Services
  10. SBIR PHASE I- TOPIC 247- PORTABLE E-TECHNOLOGY DIET AND PHYSICAL ACTIVITY TOOLS F

    SBC: APPLIED MEDIA ANALYSIS, INC.            Topic: N/A

    Applied Media Analysis, Inc (AMA) proposes to collaborate with the George Washington University Weight Management Program and Peaksware LLC to demonstrate the technical feasibility of MobileVision DietMonitor, a software-based solution which uses existing camera-enabled smart phones to provide enhanced capabilities for diet and health monitoring. Our system will allow users to monitor, track , and ...

    SBIR Phase I 2008 Department of Health and Human Services

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