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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Optimum Control of Induction Generators for Water Current Energy Harnessing

    SBC: Electro Standards Laboratory, Inc.            Topic: 815

    Optimization of generator performance and maximization of output power are difficult to attain in the generation of hydro-power. This is due to the changing water conditions and corresponding changes in the form of available energy. ESL proposes to use self-tuning controls in combination with a suitably chosen and optimized generator driven by hydro-energy and condition it for distributi ...

    SBIR Phase I 2010 Department of Commerce
  2. Efficient Processing Using New Cell Disruption Method

    SBC: ENIGMATICS, INC.            Topic: 815

    The proposed effort is aimed at the development of a new low-cost technique for extracting the fuel precursor components from marine alga cells. The effort is aimed at reducing the total production costs of alga-derived fuels, up to one-half of which may be attributed to the recovery/extraction process alone. Development of advanced processing technologies such as that proposed here is n ...

    SBIR Phase I 2010 Department of Commerce
  3. Photoacoustic Sensor for High-sensitivity Measurement of Water Vapor

    SBC: MASSTECH, INC.            Topic: 824

    We propose to build a compact, rugged airborne laser photoacoustic spectrometric (LPAS) sensor based on a tunable mid-IR diode laser for continuous, real-time measurements of water vapor, and perform field tests to qualify it for dynamic airborne in situ monitoring of upper troposphere water vapor. An innovative diode laser frequency locking technique developed by us will be utilized for tuna ...

    SBIR Phase I 2010 Department of Commerce
  4. Novel Targeted Therapy for Breast Cancer

    SBC: A&G PHARMACEUTICAL, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Breast cancer remains one of the top three cancers to affect and cause mortality in women. Major shortcomings with current treatment are the high level of side effects induced in patients and insufficient efficacy, particularly for patients with metastatic disease. Targeted cancer therapy is designed to treat only the cancer cells and minimize damage to healthy ...

    SBIR Phase II 2010 Department of Health and Human Services
  5. TB Diagnostics at the Point of Care

    SBC: AKONNI BIOSYSTEMS INC.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Of all diseases, Tuberculosis (TB) represents one of, if not, the greatest health disparity between whites and minorities [1]. To be specific, for every TB-infected white person in the United States, there are an estimated 9 African-Americans, 8 Latinos, 6 Native Americans, 23 Asians, and 21 Native Hawaiian/Pacific Islanders with this disease [2]. Compounded wi ...

    SBIR Phase I 2010 Department of Health and Human Services
  6. Combination Treatment of tPA and Apyrase for Stroke

    SBC: APT THERAPEUTICS, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): Human apyrase represents a highly promising therapy for acute ischemic stroke which is a leading cause of death and disability with almost no effective therapy for most patients. Using a protein informatics approach, we have successfully engineered a human apyrase which exhibits significantly higher enzymatic activity and platelet inhibition than the wild-type ...

    SBIR Phase II 2010 Department of Health and Human Services
  7. Combination Therapy of Aspirin and Apyrase for Stroke

    SBC: APT THERAPEUTICS, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): Human apyrase represents a highly promising therapy for acute ischemic stroke which is a leading cause of death and disability with almost no effective therapy for most patients. This enzyme strongly inhibits platelet activation and aggregation with modest bleeding risk. We will validate hypothesis that in thromboembolic model of stroke in rats, combination tre ...

    SBIR Phase I 2010 Department of Health and Human Services
  8. TGF-beta Antagonists for Accelerating Wound Healing

    SBC: AUXAGEN, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Every year in the United States, gt1.25 million people suffer from burns, 6.5 million have chronic skin ulcers caused by pressure, venous stasis or diabetes mellitus and 0.25 million have keloids sufficiently severe to require surgery. Burn treatment costs 1.8 billion per year in the US. The treatment of persons with chronic skin ulcers costs 13 billion per y ...

    SBIR Phase II 2010 Department of Health and Human Services
  9. Development of a novel human rhinovirus vaccine

    SBC: BIOLOGICAL MIMETICS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Human Rhinoviruses (HRV) cause approximately one third of the 60 million cases of common cold each year in the US and therefore are one of the most economically important human diseases of developed countries. Although rhinoviruses are not generally considered killer viruses, more recent studies have shown that rhinoviruses are a significant source of hosp ...

    SBIR Phase I 2010 Department of Health and Human Services
  10. New Needle for Two-Needle Hemodialysis

    SBC: BIOMEDICAL ENTERPRISES, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Studies performed with phase I SBIR grants 1R43DK55385-01A1 and 1 R43 DK59062-01A1 and phase II SBIR grants 2R44DK059062-02A1 and 5R44DK059062-04 have demonstrated the following: a) A new hemodialysis(HD) venous needle (NVN) with three jets is hemodynamically superior to the current venous needle (CVN) because it decreases the velocity of the vascular access ...

    SBIR Phase II 2010 Department of Health and Human Services

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