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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Universal Attenuated Sporozoite Vaccine and Challenge System

    SBC: SANARIA INC.            Topic: NIAID

    ABSTRACT Sanaria s Plasmodium falciparumPfsporozoiteSPZvaccines development program is receiving global supportTrials of PfSPZ Vaccineradiation attenuated PfSPZor PfSPZ CVacPfSPZ Chemoprophylaxis Vaccineadministered by direct venous inoculationDVIincludingadults to infants were initiated in DecemberTanzaniaU Sor will be initiated in earlyin MaliKenyainfantsGhanaEquatorial GuineaGermany andaddition ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Advancing a Glioma Immunotherapy

    SBC: IN CYTU, INC.            Topic: 102

    DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Protease chain reactions for molecular analysis of cancer markers

    SBC: POTOMAC AFFINITY PROTEIN LLC            Topic: 102

    DESCRIPTION provided by applicant Our objective is to develop a Protease Chain Reaction technology ProCR that will enable ultra sensitive and highly quantitative detection of cancer markers The basic element of a protease chain reaction is a protease inhibitor complex The protease is inactive when bound to the inhibitor but once freed is capable of cleaving the inhibitor and releasing ad ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Software for improved accuracy and rapid tracking of kinematics from dynamic Xray

    SBC: C-MOTION, INC.            Topic: NIAMS

    DESCRIPTION provided by applicant Orthopaedic disorders are a leading cause of disability in the U S with arthritis and or spine problems adversely affecting quality of life fo more than of adults While advances in diagnostic imaging have greatly improved our ability to detect structural changes in musculoskeletal tissues they typically reveal little about joint function There is evid ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Nanometer Precision Absolute Linear Interferometer

    SBC: AUTOMATED PRECISION, INC.            Topic: 090101

    The goal of this Phase I project is to develop an affordable, accurate, and rapid absolute interferometric length measurement technique with improved repeatability and accuracy. API has a patent-pending technology, Frequency-Modulated Time-to-Frequency Mapping Interferometer (FM-TFMI), that is an absolute interferometer capable of measuring at high speed and with exceptionally high accuracy. The T ...

    SBIR Phase I 2016 Department of CommerceNational Institute of Standards and Technology
  6. High-Throughput Low-Cost Manufacturing of Engineered MRI Contrast Agents

    SBC: WEINBERG MEDICAL PHYSICS, INC.            Topic: 90103

    New shape-engineered iron-based microscopic contrast agents (MCAs) for magnetic resonance imaging promise to increase diagnostic accuracy while reducing side effects, and enhance scientists’ ability to track stem cells. Currently, techniques used for making multispectral microscale contrast agent particles are cost prohibitive. In Phase I, an innovative technique (employing template-guided elect ...

    SBIR Phase II 2016 Department of CommerceNational Institute of Standards and Technology
  7. Resonant Scan Lens for Scanning Beam LIDAR

    SBC: z-senz LLC            Topic: 90501

    The objective of this Phase II project is to research, develop, and commercialize a resonant scan lens (RSL) for use in a resonant light detection and ranging (R-LIDAR) distance sensor. R-LIDAR uses a resonant optomechanical system to generate a beam scan. While resonant optomechanical systems produce high-speed and large field-of-view (FOV) scans from a miniature form factor, the beam scans lack ...

    SBIR Phase II 2016 Department of CommerceNational Institute of Standards and Technology
  8. Computerizing NIAAA's Best Practices for Youth Screening and Brief Intervention

    SBC: COG ANALYTICS, LLC            Topic: 400

    DESCRIPTION provided by applicant The early onset of alcohol misuse during adolescence is a widespread problem in the U S Studies have consistently documented both the short and long term adverse neurophysiological impacts and health risk behaviors associated with alcohol misuse during adolescence Given the magnitude of this problem and its myriad consequences preventing early initiation of ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. A High Resolution Radiation Therapy Dosimetry system

    SBC: DOSEIMAGING, LLC            Topic: 399

    DESCRIPTION provided by applicant Modern radiation therapy treatment modalities such as intensity modulated radiation therapy are associated with complex dose distributions and sharp dose gradients Experimental dose validation using multidimensional high spatial resolution dosimeters is mandatory The product to be developed is a novel high resolution dosimetry system that combines reusabil ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. PEGYLATED PEPTIDES LIGANDS TARGETING RADIATION-INDUCIBLE RECEPTORS ON CANCER

    SBC: Medical Guidance Systems LLC            Topic: 102

    DESCRIPTION provided by applicant The proposed research is the study of new paradigms in both the treatment of cancer and cancer drug development This platform technology will markedly expand the number of cancer specific surface receptors and antigens that can be targeted for drug delivery using peptide ligands The general principle of this new technology is that cancer cells respond to ioni ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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