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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. UNIQUE IMMUNOASSAYS FOR DETECTION OF CIGUATOXIN AND RELATED MARINE TOXINS USING MONOCLONAL ANTIBODIES

    SBC: Moana Bioproducts Inc            Topic: N/A

    THIS PROPOSAL DESCRIBES A UNIQUE AND HIGHLY SIMPLIFIED IMMUNOLOGICAL PROCEDURE USING A MONOCLONAL ANTIBODY TO CIGUATOXIN IN A TWO-STEP PROCEDURE. THE MONOCLONAL ANTIBODY(MAB) IS PREPARED BY THE MOUSE HYBRIDOMA TECHNIQUE, USING HIGHLY PURIFIED CIGUATOXIN CONJUGATED TO PROTEIN CARRIERS. THE MAB-CTX THUS OBTAINED IS CONJUGATED TO COLLOIDAL GOLD (< 0.45 UM DIAMETER) OR COLORED LATEX PARTICLES. THIS WI ...

    SBIR Phase I 1989 Department of Commerce
  2. SHALLOW WATER SONAR SYSTEM

    SBC: Ocean Systems Research, Inc.            Topic: N/A

    SPECIAL MILITARY NARROW BEAM ACOUSTIC PROJECTORS AND TRANSMISSION TECHNIQUES CAN BE EASILY ADAPTED FOR COMMERCIAL USE TO ENABLE FISHERMEN OR RESEARCHERS TO DETECT,LOCATE, AND QUANTIFY BIOLOGICAL TARGETS WITH VERY HIGH ACCURACY IN SHALLOW WATER. THE PROPOSED EFFORT WILL PROVIDE A METHOD FOR PRODUCING VERY NARROW ACOUSTIC BEAMS WITH VIRTUALLY NO SIDELOBES FROM A SMALL APERTURE PROJECTOR ARRAY. ALSO ...

    SBIR Phase I 1989 Department of Commerce
  3. CAMREAD-- A HIGH-SPEED OPTICAL RECOGNITION SYSTEM

    SBC: Ada Digital Systems, Inc            Topic: N/A

    AN IBM-AT-BASED MULTIFUNCTIONAL SYSTEM-CAMREAD-IS PLANNED. CAMREAD IS AN INEXPENSIVE, REAL-TIME IMAGE-PROCESSING SYSTEM WITH THE CAPABILITY OF HIGH-SPEED CHARACTER RECOGNITION TO SOLVE THE PROBLEM OF CONVERTING PRINTED DOCUMENTS INTO MACHINE-READABLE RECORDS. DIFFERENT FROM OTHER COMMERCIALLY AVAILABLE EXPENSIVE MONOFUNCTIONAL READING MACHINES, THIS SYSTEM HAS MANY UNIQUE FEATURES. FIRST, IT IS A ...

    SBIR Phase I 1989 Department of Health and Human Services
  4. USING TELEPHONE MEDIA TO PLAN FOR RETIREMENT

    SBC: Associated Enterprises Inc.            Topic: N/A

    N/A

    SBIR Phase I 1989 Department of Health and Human Services
  5. GRAPHICAL INTERNATIONAL FOOD RETRIEVAL/ANALYSIS PROGRAM

    SBC: AIMS, INC.            Topic: N/A

    THE MAJOR GOALS FOR THE GRAPHICAL INTERNATIONAL FOOD RETRIEVAL AND ANALYSIS PROGRAM SYSTEM WERE TO COMPLETE THE INTERACTIVE PORTION OF THE SYSTEM AND TO ALLOW FOR THE INTEGRATION OF OTHER DATABASES. THE MICROSOFT WINDOWS SOFTWARE UNDER DOS WAS CHOSEN FOR DEVELOPMENT DUE TO ITS LARGER USER BASE. DURING PHASE I, INFORMATION MANAGEMENT SERVICES, INC., DEVELOPED THE SYSTEM INTO A FULLY INTERACTIVE, GR ...

    SBIR Phase I 1989 Department of Health and Human Services
  6. EFFECTS OF ANGIOGENESIS FACTORS ON SKIN FLAP SURVIVAL

    SBC: Angiogen, Inc.            Topic: N/A

    IN SPITE OF THE COMMON USE OF SKIN GRAFTS AND SKIN FLAPS IN PLASTIC AND RECONSTRUCTIVE SURGERY, SERIOUS COMPLICATIONS STILL ARISE. THE COMPLETE OR PARTIAL NECROSIS THAT CAN OCCUR IN SURGICAL FLAPS OR GRAFTS IS DUE TO PROLONGED TISSUEISCHEMIA THAT COMPROMISES TISSUE BLOOD FLOW. PROMPT REVASCULARIZATION OF THE GRAFT OR FLAP BY ANASTOMOSES AND NEOVASCULARIZATION IS A MAJOR DETERMINANT OF THE SUCCESS ...

    SBIR Phase I 1989 Department of Health and Human Services
  7. ULTRASENSITIVE NICKEL DETERMINATIONS FOR TOXICOLOGY

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    INCREASINGLY STRINGENT REQUIREMENTS ARE BEING PLACED ON THE DETECTION AND ACCURATE CHARACTERIZATION OF TOXIC ELEMENTS INENVIRONMENTAL HEALTH. THE TOXICOLOGY OF NICKEL, IN ELEMENTAL AND METALLO-ORGANIC FORM, HAS BEEN THE SUBJECT OF MUCH ATTENTION IN RECENT YEARS. NICKEL HAS BEEN IMPLICATED IN NUMEROUS CARCINOGENIC, MUTAGENIC, METABOLIC, AND EPIDEMIOLOGICAL STUDIES. AS THE KNOWLEDGE OF BIOLOGICAL ME ...

    SBIR Phase I 1989 Department of Health and Human Services
  8. DEVELOPMENT OF A SERUM-FREE MEDIUM FOR CELLS

    SBC: Biological Research Faculty &            Topic: N/A

    N/A

    SBIR Phase I 1989 Department of Health and Human Services
  9. MOLECULES PROBES FOR HUMAN B-LYMPHOTROPIC VIRUS

    SBC: Bio-molecular Technology, Inc.            Topic: N/A

    THE HUMAN HERPES VIRUS TYPE 6 (HHV-6) IS A NOVEL HERPES VIRUS ISOLATED FROM FRESH HUMAN BLOOD MONONUCLEAR CELLS. ALTHOUGH NOT EXCLUSIVELY ASSOCIATED WITH ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS), HHV-6 MAY PLAY A ROLE IN LYMPHOPROLIFERATIVE ABNORMALITIES. AS A RECENT VIRUS ISOLATE, LITTLE IS KNOWN OF THE BIOLOGICAL PROPERTIES OF HHV-6, AND FEW REAGENTS ARE AVAILABLE TO INVESTIGATORS IN THE FIELD ...

    SBIR Phase I 1989 Department of Health and Human Services
  10. ANTIBODY PROBES FOR HUMAN B-LYMPHOTROPIC VIRUS

    SBC: Bio-molecular Technology, Inc.            Topic: N/A

    THE HUMAN HERPES VIRUS TYPE 6 (HHV-6) IS A NOVEL HERPES VIRUS ISOLATED FROM FRESH HUMAN BLOOD MONONUCLEAR CELLS. ALTHOUGH NOT EXCLUSIVELY ASSOCIATED WITH ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS), HHV-6 MAY PLAY A ROLE IN LYMPHOPROLIFERATIVE ABNORMALITIES. AS A RECENT VIRUS ISOLATE, LITTLE IS KNOWN OF THE BIOLOGICAL PROPERTIES OF HHV-6, AND FEW REAGENTS ARE AVAILABLE TO INVESTIGATORS IN THE FIELD ...

    SBIR Phase I 1989 Department of Health and Human Services

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