Award Data

This project will develop a computer-assisted consultation system for clinical radiologists in thedetection of lung nodules (cancer) on chest radiographs. An automated screening of digital chestradiographs can be further developed when this system is fully tested in various clinical settings. Thesuccess of this project will inspire revolutionary improvements in other cancer diagnostic proceduresth ...

This project will develop a computer-assisted consultation system for clinical radiologists in theclassification of benign and malignant (cancer) calcifications on mammograms. An automated screeningof digital mammograms can be further developed when this system is fully tested in various clinicalsettings. The success of this project will inspire revolutionary improvements in other cancer diagnosti ...

NATIONAL ATTENTION HAS REFOCUSED ON FINDING NEW ECONOMIC DEVELOPMENT INITIATIVES TO HELP RURAL ECONOMIES. RURAL TOURISM CAN REVITALIZE THESE ECONOMIES BUT IS HINDERED BY POOR RURAL INFRASTRUCTURE, ISOLATION, POOR ACCESS TO RESOURCE INFORMATION, AND INSUFFICIENT PROMOTION FUNDS. TELESONIC PROPOSES TO DEVELOP AND TEST THE FEASIBILITY OF INTRODUCING A UNIQUE MULTIMEDIA TELEPHONE TECHNOLOGY PROGRAM TO ...

THE GOAL OF THIS RESEARCH IS TO PRODUCE ACAP, A PERSONAL COMPUTER-BASED ADVISOR FOR FAMILIES AND CAREGIVERS OF ALZHEIMER'S AND OTHER DEMENTED PATIENTS. UTILIZING EXPERT SYSTEM TECHNIQUES,THE SYSTEM IS INTENDED TO PROMOTE AN UNDERSTANDING OF DEMENTIA RELATED DISEASE PROCESSES, PROVIDE AN OVERVIEW OF THE MEDICAL, CUSTODIAL CARE, FINANCIAL, AND LEGAL PROBLEMS NORMALLY ENCOUNTERED, AND IDENTIFY SPECIF ...

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We will develop and validate a new assay system to replace existing immunocytochemicalassays for detecting occult micrometastases in bone marrow of patients with primary breast cancer.This assay would offer simplicity, low cost, and a quantitative end point. The assay is based on aninnovative amplification mechanism, the bacterial chain reaction (BCR), which is potentially capable oflowering the d ...

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A NOVEL CONFOCAL MODULATION SYSTEM THAT CONVENIENTLY ATTACHES TO ALMOST ANY CONVENTIONAL MICROSCOPE AND CONVERTS IT INTO A CONFOCAL MICROSCOPE HAVING INNOVATIONS AND CAPABILITIES NOT AVAILABLE TOGETHER IN CURRENT CONFOCAL MICROSCOPES WILL BE DEVELOPED. THE SPECIFIC AIMS ARE TO MODEL, BUILD, AND TEST THE CRUCIAL OPTICAL SUB-COMPONENTS OF THE INVENTION FOR USE IN MODELING AND TESTING OVERALL SYSTEM ...

Association of human papillomaviruses (HPV) infection an carcinogenesis of the uterine cervixhas been firmly established both epidemiologically and in the laboratory. Several HPV subtypes are nowconsidered to be contributing factors for cervical cancer. However, the association of HPV and oralcancer has not been fully investigated. The Southern blotting technique, HPV-32, HPV-13 and HPV-6have been ...

Dysfunctional genes and aberrant expression of regulatory genes are speculated to be key eventsin human tumorigenesis. In breast cancer, examples of these genes include, but are not limited toc-erbB-2 (HER-2/neu), int-2, and c-myc, (oncogenes), and p53 (tumor suppressor gene). Many otherundefined oncogenes and tumor suppressor genes may also play a role in breast cancer development.We propose to d ...