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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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High-Resolution, Spinal Cord Stimulation for Non-Opioid Treatment of Neuropathic Pain
SBC: MICRO-LEADS INC Topic: 000In this SBIR FastTrack proposal, Micro-Leads will develop HD64—a high-resolution, 64- channel spinal cord stimulation therapy to provide more pain relief with greater specificity for those suffering from chronic neuropathic pain and opioid dependence. Over 25 million in the U.S. suffer from debilitating pain in the trunk and extremities and 55% depend on opioids to ease their suffering. Opioid a ...
SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
A Novel Immunological Probiotic for Treating Inflammatory Bowel Disease
SBC: Rise Therapeutics, LLC Topic: 300Project Summary The goal of this project is to develop a novel immunologically designed probiotic therapy to inhibit gut inflammatory processes for the treatment of inflammatory bowel disease (IBD). Over 3 million adults in the U.S. suffer from IBD, an umbrella term encompassing two chronic inflammatory diseases of the gastrointestinal tract: Crohn’s disease (CD) and ulcerative colitis (UC)6. IB ...
SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
Development of an ALDH2-Targeting RNAi Therapeutic for Alcohol Use Disorders
SBC: Dicerna Pharmaceuticals, Inc. Topic: 150Abstract Alcohol Use Disorder (AUD) is a chronic condition characterized by compulsive alcohol use, loss of control over alcohol use, and a negative emotional state when not using alcohol, with such use associated with a range of medical, psychological, social, economic, and personal problems. AUD is global and prevalent; in a survey of over 36,000 adults in the US, AUD had a 12-month prevalence o ...
SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
A Phase 2a Clinical Study of a Cardiac Hormone for the Outpatient Treatment of Worsening Heart Failure
SBC: MADELEINE PHARMACEUTICALS INC Topic: NHLBIAbstract/Summary Madeleine Pharmaceuticals, Inc. The Specific Aim of this SBIR Phase IIB proposal is to carry out the first phase 2a clinical trial of our Phase 2 program using rMP3167, a recombinant human form of the naturally occurring cardiac hormone proANP 31-67, for the treatment of worsening heart failure (WHF). This is part of our broad drug development objective, supported by leading cardi ...
SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
Immune modulation of radiation therapy with Flt3 ligand
SBC: AVANT IMMUNOTHERAPEUTICS, INC. Topic: 102Project Summary This proposal is a unique collaboration between a small, but full capability biotechnology company and an academic institution specialized in radiation therapy. Stereotactic radiosurgery (SRS) is being frequently used to control macroscopic tumor in patients with limited metastases. The success of SRS in controlling macroscopic disease has generated enthusiasm in combining SRS with ...
SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
A Mightier healthcare system: Introducing a game-based pediatric mental health intervention into payor-sponsored care to evaluate financial and clinical outcomes
SBC: Neuromotion, Inc. Topic: 104PROJECT SUMMARY Access to effective pediatric mental health treatment is a major public health concern in the United States as paucity of pediatric providers leading to long wait times, financial burden, and stigma pose significant barriers to treatment. Digital mental health promises to remedy many chronic problems we face in providing timely and accessible mental health interventions to children ...
SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
Optimizing SWELL1 modulators to treat non-alcoholic steatohepatitis
SBC: Senseion Therapeutics, Inc. Topic: 300Non-alcoholic fatty liver (NAFL) and its progression to advanced stage non-alcoholic steatohepatitis (NASH) is a growing health concern, with 83.1 million Americans affected in 2015, and projections to reach 100.9 million by 2030. Metabolic syndrome and Type 2 diabetes (T2D) are considered significant pathophysiological contributors to NAFL-NASH progression, therefore, novel therapeutic strategies ...
SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Online System for Primary Care to Prevent and Address Teen Substance Use
SBC: CHADIS, INC. Topic: NIDASubstance use usually (90%) begins during adolescence, causing brain and liver damage, risky sexualand driving behavior, and potentially leading to addiction therefore prevention and earlyintervention programs targeting teens are needed to prevent this morbidity, gain productive yearsof life and reduce costs.This proposal presents innovations to overcome the barriers toeffectively addressing teen ...
SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
PfSPZ Vaccine for Malaria: Towards a Successful Biologics License Application and Commercialization
SBC: SANARIA INC. Topic: NIAIDABSTRACT The WHO estimates that in 2017, malaria caused 219M clinical episodes and 435,000 deaths worldwide. Despite annual investments rt$3 billion for intensive control measures, 2017 was the third consecutive year in which there was no decrease in malaria, indicating existing tools are inadequate to make further progress. There is an urgent unmet medical need for a vaccine that prevents malaria ...
SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
Online system for identifying and addressing teen depression in primary care
SBC: CHADIS, INC. Topic: 104This proposal presents innovations to addressing teen depression during routine check-up visits through further development of an online clinical process support system called CHADIS. The primary care provider remains in the center of the process with his/her prior relationship with the family and humanity enabled with computer assistance prior to the encounter as well as moment of care reminders ...
SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health