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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Antithrombotic Therapy with No Bleeding Risk for PCI
SBC: APT THERAPEUTICS, INC. Topic: yAdjunctive antithrombotic treatment with dual antiplatelet therapyaspirinP Yantagonistplus anticoagulantheparin or bivalirudinis a guideline mandated for percutaneous coronaryinterventionPCIpatientsDespite aggressive antithrombotic therapyhowevermyocardialperfusion after PCI remains inadequate in many patientsReocclusion from recurrent thrombosiscontinues to occurand dose limiting bleeding occurs ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Development of small molecule TLR5 inhibitors for rheumatoid arthritis therapy
SBC: MICROBIOTIX, INC. Topic: NIAAbstractApproximatelymillion Americans have rheumatoid arthritisRAwhich is one of the most common chronic autoimmune disorders in the older populationThere is no cure for RAand up toof patients do not respond to current therapiesAs a resultdisease progression leads to joint destruction and severe disability in the elderlyThereforethe identification of a novel therapeutic strategy used alone or in ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Inhibitors of Pseudomonas aeruginosa efflux pumps to combat multi-drug resistance
SBC: MICROBIOTIX, INC. Topic: NIAIDAbstract Multi drug resistanceMDRin Gram negative pathogensincluding Pseudomonas aeruginosaposes a significant threat for effective treatment of infections caused by these organismsA major component in the development of the MDR phenotype in Paeruginosa is overexpression of the Resistance Nodulation DevelopmentRNDfamily efflux pumpswhich pump antibacterial agents and biocides out of the celland ar ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Research and screening platform for Alzheimer's and other chronic diseases
SBC: SCANOGEN INC. Topic: NIASummary Early diagnosis of chronic diseases makes possible early treatment initiationBloodstream miRNA panels are being pursued for screening and diagnosis of the most important chronic diseasesRecentlythere has been a particular interest in Alzheimer s diseaseADmiRNA panelsIf successfulthese panels may become part of regular medical check upsHowevertheir development and application is obstructed ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
An Implantable and High-Density, Multiplexed Micro-ECoG System
SBC: MICRO-LEADS INC Topic: 105DescriptionThe mechanisms underlying brain functionssuch as perceptionmotor controllearning and memoryin health and disease result from the coordinated responses of neurons distributed across multiple brain regionsHoweverconventional electrode technologies have not scaled to capture this networked activityResearchers are forced to compromise between low resolution over large areas of the brain or ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Screening for rAAV transduction enhancers
SBC: MICROBIOTIX, INC. Topic: NIAIDABSTRACT Recombinant adeno associated virusrAAVis a promising gene delivery vector for therapeutic and vaccine applicationsbut its low transduction efficacy currently limits its utilityThe primary reasons for low transduction efficacy are as followsiinefficient trafficking of the rAAV genome to the nucleusiiinefficient host cell mediated synthesis of double stranded DNA from the single stranded ge ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Platelet Bioreactor for Treatment of Radiation-Induced Thrombocytopenia
SBC: PLATELET BIOGENESIS, INC Topic: RPlatelet Biogenesis is developing a microfluidic bioreactor that reproduces key features of adult bone marrowphysiological microenvironmentto produce human plateletsPLTsPLTs are thebandaidsof the bloodstreamresponsible for clot formation and blood vessel repairLow PLT count is a significant consequence of a radiation accident or deliberate nuclear attackfor which PLTs are a critical first line the ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Selection of a device for intranasal administration of a mucosal vaccine for HSV
SBC: Biomedical Research Models, Inc. Topic: RGlobally an estimated of the human population is infected with HSV including andgt of the U S adult population Genital herpes is associated with an increased risk of HIV acquisition and transmission of HSV infection can cause neonatal herpes with high infant mortality HSV infection in the adult population has increased substantially in the past two decades despite the availabil ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Highly specific HIV mRNA detection method with global subtype coverage to monitor latency reversal in patients
SBC: ACCELEVIR DIAGNOSTICS LLC Topic: NIAIDProject Summary Abstract Human immunodeficiency virus type HIV is a retrovirus that infects CD T cells of the immune system If left untreated HIV infected individuals will progress to AIDS and may ultimately die as a result Combination antiretroviral therapy is extremely effective at stopping the replication of HIV in infected individuals Despite the success of this therapy at sup ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Improving access to vision correction for health disparity populations with the QuickSee: an accurate, low-cost, easy-to-use objective refractor
SBC: PLENOPTIKA, INC. Topic: NIBIBSummary The principal goal of this proposal is to increase the accuracy and precision of a low cost autorefraction device called the QuickSeein order to improve access to refractive eye care for underserved populationsPoor vision due to a lack of eyeglasses is highly prevalent in low resource settings throughout the world and significantly reduces quality of lifeeducationand productivityThe existi ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health