Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Marketing Strategic Plan and Distribution Logistics for Sanaria PfSPZ Vaccine against Malaria.

    SBC: SANARIA INC.            Topic: NIAID

    ABSTRACT The development of Sanaria s Plasmodium falciparumPfsporozoiteSPZbased vaccines is receiving overwhelming global support after the publication inin Science of clinical data showingprotection against controlled human malaria infectionCHMIfollowing intravenous administration ofdoses of SanariaPfSPZ Vaccinecomposed of purifiedasepticradiation attenuatedcryopreserved PfSPZ meeting all regulat ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Therapy Management System for Model-Based Behavioral Interventions

    SBC: Experiad LLC            Topic: 104

    In this Phase II SBIR applicationExperiad Solutions proposes to complete the development of Motivitya new type of software that has the potential to modernize the practice of behavioral therapy for autismApplied Behavior AnalysisABAis an evidence based autism treatment that is practiced by overBoard Certified Behavior AnalystsBCBAsin the USBCBAs analyze a child s unique needsthen construct an indi ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Improved long-term biocompatibility of coronary stents by plasma coating process

    SBC: NANOVA INC.            Topic: NHLBI

    Improved long term biocompatibility of coronary stents by plasma coating process Abstract Drug eluting stentsDEShave been widely used to treat patients of coronary heart diseaseCHDdue to their better ability to control restenosis than bare metal stentsBMSHoweverthere is a high risk of late in stent thrombosis associated with DES after implantation in patientswhich could lead to fatal heart attack ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Antithrombotic Therapy with No Bleeding Risk for PCI

    SBC: APT THERAPEUTICS, INC.            Topic: y

    Adjunctive antithrombotic treatment with dual antiplatelet therapyaspirinP Yantagonistplus anticoagulantheparin or bivalirudinis a guideline mandated for percutaneous coronaryinterventionPCIpatientsDespite aggressive antithrombotic therapyhowevermyocardialperfusion after PCI remains inadequate in many patientsReocclusion from recurrent thrombosiscontinues to occurand dose limiting bleeding occurs ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Novel non-invasive antigen detection assay for the diagnosis of active visceral leishmaniasis and to monitor the therapy efficacy of this disease

    SBC: DETECTOGEN INC.            Topic: NIAID

    ABSTRACTThe overall goal of this Phase II project is to validate novel leishmanial protein biomarkers for development of a non invasive urine based assay to diagnose active visceral leishmaniasisVLand to monitor the therapeutic efficacy of this serious diseaseVL is endemic incountriesaffectspeople a year and kills more thanof them children under ageVLalso known as kala azaris caused by parasites o ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. OnTrack> An Online Role-Playing Game

    SBC: C4 Innovations, LLC            Topic: 104

    Project Summary First episode psychosis is a serious mental health condition that affects youth and young adultsoften between the ages ofandThe illness is marked by hallucinationsdelusionswithdrawalpoor organization skillsand diminished cognitive and social functioningRecent research has demonstrated that programs designed to treat people experiencing early psychosis can reduce hospitalizationdecr ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Evidence-Based Pain Intervention for Veterans: Leveraging Mobile & Social Media

    SBC: Pro-Change Behavior Systems Inc            Topic: NCCIH

    Chronic musculoskeletal pain creates a significant public health burdenand Veterans are disproportionately affectedThe frequency and extent of co occurrence of pain and PTSDpain and Traumatic Brain InjuryTBIall three conditionsPost deployment Multi symptom DisorderPMDand other multi symptom syndromes can complicate and reduce the effectiveness of pain treatmentFurthermorethe majority of Veterans d ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. AVGN7, a Novel Gene Therapeutic for Treating Cancer Cachexia

    SBC: Aavogen, Inc.            Topic: 102

    PROJECT SUMMARYThe skeletal muscle wasting that occurs with cancer cachexia compromises quality of life and is both directly and indirectly responsible for cancer mortalitiesTumor derived and tumor responsive factors as well as many therapeutics themselves contribute to the cachectic statealthough nutritional support has little if any positive effect on restoring striated muscle mass or functionTh ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Validation of an In Vitro Human Airway Model for Regulatory Toxicity Testing

    SBC: Mattek Corporation            Topic: NIEHS

    Results of Phase II research indicate that formal validation of the EpiAirwayin vitro human bronchial tissue model for predicting toxicity of inhaled chemicals is an attainable goalThe proposed Phase IIB cooperative agreement project is intended to realize this goal by conducting formal ring trial validation studies that will be submitted to regulatory agencies and the Organization for Economic Co ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Rapid Molecular Detection of Tuberculosis without PCR amplification

    SBC: SCANOGEN INC.            Topic: NIAID

    Project Summary TuberculosisTBis a major global burden that killsmillion people every yearTB mostly affects developing countriesbut the rise of multi drug and extensively drug resistant strains is a global threatIn order to control and eradicate this diseaseit is imperative to have adequate tools to detect active TB in limited resource settings and point of carePOCsettingswhich is where most TB pa ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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