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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. TheSieve

    SBC: Cyber Point International, LLC            Topic: NA

    We propose to create an advanced forensic analysis tool called TheSieve. This tool will use machine learning techniques that can classify files as malicious or benign as well as suggesting files for closer inspection. Built upon custom enhancements to the National Software Reference Library (NSRL), TheSieve will allow forensic investigators to spend theirvaluable time examining the most significan ...

    SBIR Phase I 2018 Department of CommerceNational Institute of Standards and Technology
  2. Development of a Rapid Monitoring System for Detection of Pathogens in Marine Aquaculture Operations

    SBC: InnovaPrep, LLC            Topic: 836

    TECHNICAL ABSTRACT: InnovaPrep proposes to develop a rapid sample-to-answer monitoring system for detecting pathogens in marine aquaculture waters. An assessment of industry needs will include a kickoff meeting with NOAA and a visit to Toby Island Bay Oyster Farm. Following the assessment and report, a TRL-4 breadboard prototype system will be developed that will include the combination of sample ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  3. Topic 378: mPROS: Mobile PRO-CTCAE Administration System for Post-Radiation Toxicities

    SBC: Intelligent Automation, Inc.            Topic: NCI

    The problems this contract is addressing include making it easy for patients to report toxicities after radiation therapy so that they can be timely and accurate and so that they can be incorporated into a medical database for use by medical professionals. This would allow the app to recommend (when appropriate), and for clinicians to intervene, with appropriate treatments and will lead to better ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health

    SBC: Otomagnetics, Inc.            Topic: NCI

    Our company has invented a magnetic drug delivery device that we intend to develop to enable prevention of a major side effect of chemotherapy in children. Cisplatin and carboplatin chemotherapy regimens can lead to severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss is FDA listed on-label as a dose limiting toxicity. Hearing loss in kids has a dramatic impact on the ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Topic 343- MindCap: Monitoring for Cognitive Impairment and Dyfunction in Cancer Patients

    SBC: Intelligent Automation, Inc.            Topic: NCI

    Persistent cognitive impairment is a frequent complaint of cancer patients undergoing chemotherapy. The current tests used to assess cognitive function are not sensitive enough to capture the degree of decline associated with cancer-related cognitive impairment (CRCI). In addition, they require professional administration and are subject to practice effects so they cannot practically be used for t ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. TOPIC 363- Caregiver Buddy: Leveraging Standards to Help Cancer Caregivers and Clinicians

    SBC: CARE PROGRESS, LLC            Topic: NCI

    This research project seeks to create innovative software that aids cancer patient caregivers,by improving their ability to access patient information, communicate with clinicians, and provide peer support. We seek to leverage the insights of stakeholders and subject matter experts as well as industry standards to enhance a caregiver facing SmartPhone app and related software developed in Phase I ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. AMADEUS: Acute Marijuana Intoxication DetectionUsing Digital Markers

    SBC: Intelligent Automation, Inc.            Topic: NIDA

    NIH through NIDA solicits the research and development of digital markers for detection of marijuana intoxication and cognitive impairmentThe goal of this project is to identify the most appropriate among candidate digital markerscognitive and physiologicalto detect driving related impairments due to acute Marijuana use and to develop a system consisting of wearablesa mobile appand accompanying ma ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. The purpose of this contract is to identify several cellular factors that have a major impact on production of a full-length HIV-1 envelope trimer without altering its native antigenic properties.


    million adults and more thanchildren become infected with HIV each yearAn effective HIV vaccine is a one time intervention that is extremely cost effective compared with the cost of lifelong treatmentThe classical vaccination approaches that have been successful in the control of various viral diseases by priming the adaptive immunity to recognize the viral envelope proteins have failed in the cas ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. The objective of this contract is to develop chemically modified mimics of microRNAs with improved activity and stability for the treatment of many diseases

    SBC: miRecule            Topic: NIAID

    Approximatelymillion people are currently living with human immunodeficiency virusHIVinfection worldwideWith no curative therapy on the horizonpatients must be on antiretroviral therapyARTfor decades to manage their diseaseBecause ART targets only actively replicating virustreatment interruption or ART failure leads to rebound of latent virusRNA therapeutics have shown great promise as a new mecha ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Novel Vaccine Technologies and Strategies to Promote Sustained Vaccine Efficiency


    The overarching objective of this proposal is the identification of novel vaccination regimen sleading to improved malaria vaccine efficacyThe medical need for such a vaccine remains compellingTo accomplish this goaltwo attenuatedheterologous viral vaccine vectorsrecombinant vesicular stomatitis virusrVSVand recombinant Isfahan virusrISFVabundantly expressing Plasmodium falciparum circumsporozoite ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health

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