Award Data

DESCRIPTION (provided by applicant): The specific aim of this study is to develop an add-on module for the ONCAD breast MRI CAD system that will provide radiologists with additional assistance when they have suspicion of the presence of infiltrating lobula r carcinoma (ILC). The proposed research will investigate the possibility of developing, training and evaluating an ILC- specific algorithm tha ...

DESCRIPTION (provided by applicant): Respiratory syncytial virus (RSV) is the leading viral cause of lower respiratory illness and hospitalization in young children and has long been recognized as a priority disease for a vaccine. RSV presents many challen ges for vaccine efficacy. Over the nearly 40 years since the failed formalin-inactivated RSV vaccine great strides have been made in understand ...

DESCRIPTION (provided by applicant): The specific aims of this Phase I SBIR proposal are to determine the feasibility of a novel detection technology for rapid and sensitive detection of influenza virus. Specifically, we will determine if the manual assay is rapid (about 15 minutes), sensitive (as least 100 times as good as, or better than, an FDA approved antigen test in terms of TCID50 units/m ...

DESCRIPTION (provided by applicant): This SBIR Phase I study is designed to develop and provide to the cell culture market, significantly improved surfaces for cell growth, differentiation control, and harvesting. The combination of two recently demonstrat ed improvements (thermally-responsive polymer for facile and gentle cell/tissue release from the support surface and nanofibrillar texture for ...

DESCRIPTION (provided by applicant): One in every 8 American women develops breast cancer at some point in their lifetime. It is estimated that more than 225,000 new cases of breast cancer occur among American women each year. Breast Conserving Therapy (BC T), defined as excision of the primary tumor and adjacent breast tissue followed by radiation therapy of the breast and/or regional lymph nodes ...

DESCRIPTION (provided by applicant): We propose this Phase II SBIR program to further capitalize on the very promising results from our Phase I effort to develop a novel, handheld three-dimensional (3D) camera able to perform objective, quantitative, and t rue 3D measurements of the size, shape, volume, color, and healing status of wounds. Accurate measurement of wound healing enables clinicians t ...

DESCRIPTION (provided by applicant): Envenomations by the brown recluse spider, Loxosceles reclusa, are a significant source of morbidity in endemic regions of the United States, and misdiagnoses are common. A survey of physicians in the endemic area has shown the economic viability of an accurate diagnostic test for these spider bites. Development and testing of an optimized Loxosceles venom as ...

DESCRIPTION (provided by applicant): The pharmaceutical industry is under mounting pressure to reinvent itself due to high failure rates in the clinic and exorbitant research costs. Larger research and development budgets have not yielded the promised incr ease in medicines entering the marketplace. Clearly new approaches to drug discovery must be explored. In response, Medros was founded on a pro ...

Location P.O. BOX 755 WEST KINGSTON, RI 02892 United States 9R44MH086129-02A1 $748 985.00 2 008 A Stage-Based Expert System for Teen Dating Violence Prevention Department of Health and Human Services National Institutes of Health SBIR Y N N PHS2007-2 Pro- ...

DESCRIPTION (provided by applicant): Advanced Medical Electronics seeks to develop a wearable device for the wireless acquisition of high-density surface-electromyogram (HD sEMG) signals. A new wireless networking standard called ultra-wideband (UWB) makes possible the creation of an ambulatory research HD sEMG instrument that can transmit 128 or more channels of data in real time. High-density s ...