Award Data

THE AIM OF THIS REVISED PROPOSAL IS TO DEVELOP LEVEL IV INTERACTIVE VIDEODISC COURSEWARE TO ENABLE PERINATAL NURSES TO ATTAIN/MAINTAIN ELECTRONIC FETAL HEART MONITORING (EFHM) SKILLS SIGNIFICANT TO EARLY DETECTION/INTERVENTION IN FETAL DISTRESS. COURSEWARE WILL BE DESIGNED WITH FLEXIBILITY TO ENSURE RELEVANCE FOR PERINATAL NURSE PRACTITIONERS' CONTINUING EDUCATION NEEDS AND FOR NURSES IN BASIC/GRA ...

THE USEFULNESS OF EVENT-RELATED BRAIN POTENTIALS (ERPS), BOTH AS A RESEARCH TOOL FOR THE STUDY OF COGNITIVE PROCESSESAND FOR APPLICATIONS IN CLINICAL AND OPERATIONAL SETTINGS, IS LIMITED BY THE NEED TO SIGNAL AVERAGE OVER MULTIPLE OCCURRENCES OF THE EVENT OF INTEREST AND BY THE CONSEQUENT NEED FOR PRECISE KNOWLEDGE OF THE TIMING OF THE ELICITING EVENT. THE PROPOSED WORK WILL EXPLORE THE APPLICABIL ...

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CURRENT SOURCES OF INFORMATION ON QUESTIONABLE MEDICAL MODALITIES ARE LIMITED IN AVAILABILITY AND GENERALLY LACK CRITICAL CONTENT. THIS PROJECT WILL DEVELOP THE CAPACITY TOPROVIDE EASILY ACCESSIBLE, ONLINE COMPREHENSIVE AND DETAILEDINQUIRY RESPONSES TO PHYSICIANS. THE CENTRAL ISSUE OF HOW TO CRITICALLY EVALUATE THERAPIES THAT FOR THE MOST PART HAVENOT FOLLOWED THE TRADITIONAL SCIENTIFIC PATTERNS O ...

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THE LONG-TERM OBJECTIVES OF THIS PROJECT ARE (1) TO ESTABLISH A STABLE SOURCE OF WELL-CHARACTERIZED ANTIBODIES TO DNA ADDUCTS OF CARCINOGEN/MUTAGENS SO THAT THESE IMPORTANT PROBES CAN BE MADE AVAILABLE FOR FUNDAMENTAL RESEARCH INTO THE MECHANISM(S) OF CARCINOGENESIS, AND (2) TOPROVIDE SERVICES/ASSAY KITS FOR MONITORING HUMAN POPULATIONSFOR POSSIBLE EXPOSURE TO SOME ENVIRONMENTAL CARCINOGENS BY SCR ...

THE LONG-TERM OBJECTIVE OF THIS PROJECT IS TO ESTABLISH A STABLE SOURCE OF PURE ENDOGENOUS HEPATIC PROLIFERATION INHIBITOR (HPI) AND OTHER RELATED MODULATORS OF CELL DIVISION. THESE IMPORTANT PROBES CAN THEN BE MADE AVAILABLEFOR FUNDAMENTAL RESEARCH INTO THE REGULATION OF CELL PROLIFERATION AND DIFFERENTIATION, WHICH MAY BE A COMMON DENOMINATOR FOR MALIGNANT DISEASES AND AGING. PHASE I STUDIES INV ...

INOSITOL TRISPHOSPHATE (IP3) HAS RECENTLY BEEN SHOWN TO STIMULATE CA(2+) RELEASE IN A VARIETY OF CELL TYPES AND, THEREFORE, MEDIATES SUCH PROCESSES AS MUSCLE CONTRACTION, HORMONE SECRETION, AND LIVER METABOLISM. IN ORDER TO INVESTIGATE THE MECHANISM OF IP3 ACTION AND TO DEVELOP THERAPEUTIC DRUGS THAT ACT BY DUPLICATING OR INHIBITING IP3 ACTION, ONE ESSENTIAL LINE OF RESEARCH IS TO STUDY IP3 BINDIN ...

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