Award Data

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We will develop a computer-assisted system to improve the ability of breast sonography to distinguifrom benign lesions. These are lesions originally detected by mammography and sent to ultrasound forThe lesions are biopsied when they are classified by ultrasound as solid or indeterminate, even thoubenign at biopsy. Because of the large numbers of breast biopsies being performed, even a small impro ...

Diabetes is widely recognized as one of the leading causes of death and disability. Medical complicdiabetes can cause blindness, heart disease, stroke, kidney failure, nerve damage, and amputations.and Complications Trial researched the effect of intensive treatment on insulin dependent diabetics.that intensive treatment significantly reduces the number of complications that diabetics suffer. Thro ...

An ECC monitoring system in the form of a miniature Personal Computer Memory Card International Ass(PCMCIA) card is proposed. PCMCIA is a standard for credit card-sized ( 5mm x 86mm x 54 mm) peripherdesigned to use with notebook and handheld computers. The user can quickly remove and add these cardportable computers. Cards are manufactured that add I/0 devices to the computer, such as modems, loc( ...

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Reuse in software engineering is an exciting concept that has yet to be reliably implemented. The number of program subroutines that are truly generic (and therefore applicable across all applications) is limited. However, there are specific applications that are required by many organizations, albeit with a set of constraints specific to each organization. This project proposes to design a too ...

We have described a new technology called "preparative in situ hybridization (Prep-I.S.H.), which is capable of isolating a set of cDNA or genomic clones according to their chromosome location. The technology takes advantage of in situ hybridization of cloned DNAs to metaphase chromosome spreads, chromosome microdissection, and the polymerase chain reaction (PCR). We will use this technology to de ...

Our research decribes a strategy for producing a high density set of PCR-base microsatellite markerpolymorphic in L5178Y, the cell line used in the mouse lymphoma assay (MLA). These polymorphic marketwo detailed long range restriction maps in the vicinity of the thymidine kinase (tk-1) gene, with tdefined distances from each other and the tk-1 gene. The first, lower resolution map will define thet ...