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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. AAAPT Technology for Improving Chemotherapy

    SBC: SCI-ENGI-MEDCO SOLUTIONS, INC            Topic: NCI

    DESCRIPTION provided by applicant Dysregulation of apoptosis pathways and loss of Human Beta Defensin hBD are the common tactics adapted by cancer cells to circumvent the effects of chemotherapy Consequently high dose of chemotherapy is required to obtain a clinically relevant therapeutic index which in turn compromises safety and develops resistance to therapy The problem is acute p ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A biodegradable ophthalmic drug delivery device

    SBC: Notus Laboratories, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Our long-term research goal is to develop an ophthalmic, nanofiber-based, biodegradable device that will provide extended release of therapeutic agents to the posterior segment of the eye via transscleral and intravitr eal approaches. This platform device will address the major technical problem in the treatment of posterior eye diseases (diabetic retinopathy, ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  3. A Biological Assessment System for Cognitive Persistence

    SBC: BIOASSESSMENTS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The low frequency cardiac rhythm (LFCR) is an innovative, but underutilized, biological marker. The PI's studies show that LFCR is strongly associated with the state of cognitive persistence in controls. Cognitive persistence refers to the ability to remain on-task and inhibit impulsive off-task behavior. Additional preliminary data also suggest that children w ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  4. A Biological Assessment System for Cognitive Persistence

    SBC: BIOASSESSMENTS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The low frequency cardiac rhythm (LFCR) is a promising biological marker for psychological research. The primary goal of this project is to make the LFCR methodology more accessible to researchers by providing a both a product and extensive support services. In Phase I, a prototype system was built and used to collect simultaneous physiological and cognitive da ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  5. A Broadly Tunable Ultrashort Pulse IR OPO Pumped by a Mode-Locked

    SBC: SCIENCE & ENGINEERING ASSOC., INC.            Topic: N/A

    We propose to develop an innovative, compact ultrafast high brightness laser source, broadly tunable in the infrared for vibrationally-resolved infrared microscopy and other applications. By passive Kerr lens mode-locking of a novel diode-pumped tunable Cr:LiSAF laser, 100fs pulses will be generated at 100 MHZ repetition rate with an average power of 1W. An optical parametric oscillator (OPO) pump ...

    SBIR Phase I 1997 Department of Commerce
  6. A capsule-based bioconjugate vaccine to prevent Klebsiella pneumoniae infections

    SBC: VaxNewMO            Topic: NIAID

    PROJECT SUMMARY Klebsiella pneumoniae is an encapsulated human pathogen capable of causing a myriad of human infections. Recently, K. pneumoniae has also emerged as one the most common causes of secondary bacterial pneumonia in COVID-19 patients. Over the last 40 years, K. pneumoniae has evolved into two distinct pathotypes, known as classical K. pneumoniae (cKp) and hypervirulent K. pneumoniae (h ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  7. Accelerate Adoption of Galaxy Pro in the Biomedical Research Marketplace

    SBC: GalaxyWorks LLC            Topic: NHGRI

    Project Summary Galactic Core LLC aims to develop a robust, scalable, and managed service for performing enterprise-grade biomedical data analysis. The service will be based on the popular open-source Galaxy application (​https://galaxyproject.org/​), offering unlimited data storage and compute capabilities with an extremely powerful, flexible, and collaborative environment for analyzing data. ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Accessible Mounting and Positioning Technology

    SBC: BLUE SKY DESIGNS INC            Topic: N/A

    DESCRIPTION (provided by applicant): People using wheelchairs are more active than ever before. Their wheelchair is a mobile station, a base from which they work, play and interact. Access from their wheelchair is essential, yet people are constrained by limitations imposed by existing mounts. Accessible mounting technology increases the independence and mobility of people with disabilities, resu ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Accessible Mounting and Positioning Technology

    SBC: BLUE SKY DESIGNS INC            Topic: N/A

    DESCRIPTION (provided by applicant): People using wheelchairs are more active than ever before. Their wheelchair is a mobile station, a base from which they work, play and interact. Access from their wheelchair is essential, yet people are constrained by limitations imposed by existing mounts. Accessible mounting technology increases the independence and mobility of people with disabilities, resu ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Accessible Virtual Reality for Machinist Training Modules

    SBC: Microcompatibles, Inc.            Topic: N/A

    This proposal will emphasize outfitting a virtual classroom and creating a skills (CNC) oriented training program. The virtual classroom will involve contextual learning using a realistic simulation of the manufacturing environment. The simulation will have all of the characteristics of a machine shop, but will allow the learner to explore and experiment ("discover") in ways that would not be pr ...

    SBIR Phase I 1995 Department of Commerce
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