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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. 2-D Microfluidic Gene Scanner

    SBC: CALIBRANT BIOSYSTEMS, INC.            Topic: N/A

    Two-dimensional (2-D) DNA gel electrophores allows DNA fragments to be resolved in two dimensions based on their differences in size and sequence. Apart from nucleotide sequencing, this technique provides the only method with a theoretical sensitivity of virtually 100% for mutation detection. At present, 2-D DNA gel electrophoresis is relatively cost-effective in comparison with other mutation det ...

    SBIR Phase I 2001 Department of Health and Human Services
  2. A COMMUNICATION DEVICE FOR THE SPEECH IMPAIRED

    SBC: KIBITZER            Topic: N/A

    DESCRIPTION: This project addresses the alternative communication and computer access needs of individuals who, as a result of a neuromuscular disorder, e.g. cerebral palsy, are severely speech impaired and/or lack the fine motor control necessary to use direct selection to access an Augmentative and Alternative Communication (AAC) device or computer. Currently these indi ...

    SBIR Phase II 2001 Department of Health and Human Services
  3. A COMMUNICATION DEVICE FOR THE SPEECH IMPAIRED

    SBC: KIBITZER            Topic: N/A

    DESCRIPTION: This project addresses the alternative communication and computer access needs of individuals who, as a result of a neuromuscular disorder, e.g. cerebral palsy, are severely speech impaired and/or lack the fine motor control necessary to use direct selection to access an Augmentative and Alternative Communication (AAC) device or computer. Currently these indi ...

    SBIR Phase I 2001 Department of Health and Human Services
  4. A HEPATOCYTE SPHEROID ENTRAPMENT BIOARTIFICIAL LIVER

    SBC: ALGENIX, INC.            Topic: N/A

    APPLICANT?S DESCRIPTION: Gene therapy will allow for the treatment of both acquired and genetic diseases at the most fundamental level by introduction of therapeutic genes. Despite advances in delivery of foreign genes, achieving high and stable levels of expression has been problematic. The use of plasmid DNA for gene therapy has many advantages, including safety, accommodation of large genes, ea ...

    SBIR Phase I 2001 Department of Health and Human Services
  5. A High Throughout Protein Crystallization System

    SBC: BioSpace International            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal is directly applicable to the Protein Structure Initiative. A major bottleneck in the initiative is the capability to obtain quality diffractable protein crystals for structure elucidation. The automated DCCS system described in this proposal has been designed to minimize the effects of the protein crystal bott ...

    SBIR Phase I 2001 Department of Health and Human Services
  6. A LOW VOLTAGE ELECTROPORATION FOR GENE TRANSFER

    SBC: PORE SQUARED BIOENGINEERING            Topic: N/A

    DESCRIPTION (Verbatim from Applicant's Abstract): Our goal is to construct a prototype chamber with protocols for the manufacture of a new low-voltage electroporation (LVEP) system to transfect suspended and adherent cells under physiologic conditions. Electric field amplification results from embedding the cells into the pores of thin (13 um) insulating filters, ena ...

    SBIR Phase II 2001 Department of Health and Human Services
  7. A LOW VOLTAGE ELECTROPORATION FOR GENE TRANSFER

    SBC: PORE SQUARED BIOENGINEERING            Topic: N/A

    DESCRIPTION (Verbatim from Applicant's Abstract): Our goal is to construct a prototype chamber with protocols for the manufacture of a new low-voltage electroporation (LVEP) system to transfect suspended and adherent cells under physiologic conditions. Electric field amplification results from embedding the cells into the pores of thin (13 um) insulating filters, ena ...

    SBIR Phase I 2001 Department of Health and Human Services
  8. A method for sterilization of human plasma and platelets

    SBC: AMULET PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal is to develop a method to prolong the shelf-life and increase the safety of human platelets with a unique method of sterilization. The method delivers an agent known to kill a range of microbial pathogens in vitro including many bacterial species known to contaminate platelet concentrates, fungi, parasites, and vir ...

    SBIR Phase I 2001 Department of Health and Human Services
  9. A method for sterilization of human plasma and platelets

    SBC: AMULET PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal is to develop a method to prolong the shelf-life and increase the safety of human platelets with a unique method of sterilization. The method delivers an agent known to kill a range of microbial pathogens in vitro including many bacterial species known to contaminate platelet concentrates, fungi, parasites, and vir ...

    SBIR Phase II 2001 Department of Health and Human Services
  10. A New Tuberculin for the Diagnosis of Tuberculosis

    SBC: Sequella Inc            Topic: N/A

    DESCRIPTION (provided by applicant):Accurate diagnosis of tuberculosis (TB) infection is one of the pillars of effective TB control programs. The current tool to diagnose infection with Mycobacterium tuberculosis is the tuberculin skin test (TST). Because of the cross-reactive nature of purified protein derivative (PPD) of tuberculin, TST currently does not discr ...

    SBIR Phase I 2001 Department of Health and Human Services

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