Award Data

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to provide private and public stakeholders with new technological tools to better monitor and predict pandemics. This project is expected to modernize the tools used today by private and public laboratories to collect and purify pathogens, particularly human coronaviruses from community was ...

The broader/commercial impact of this Small Business Innovation Research (SBIR) Phase I project is the development of Artificial Intelligence (AI)-based algorithms that generate content for word-meaning video games at an affordable cost. Word-meaning games support literacy, fluency, critical thinking, and cross-cultural understanding for players of all ages and backgrounds via adaptive vocabulary ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to improve early detection and clinical management of bacteremia in patients suspected of bacterial sepsis. Over 250,000 patients die of sepsis each year in the U.S., which results in hospitalization costs exceeding $20 billion. A sepsis patient’s risk of death has been demonstrated to in ...

The broader impact of this Small Business Innovation Research (SBIR) Phase I project is to reimagine bio-manufacturing with a novel platform technology that could boost the yields of many products, including food additives, biomaterials precursors, biofuels, and pharmaceuticals. The technological advancement addresses a fundamental issue that limits conventional bio-fermentation, which is that pro ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to develop an antimicrobial muscle-regenerating biomaterial into a commercial-ready product and address volumetric muscle loss injuries. In the context of defense medicine, severe muscle trauma often occurs in environments where external factors such as sterility are not well-controlled. Th ...

The broader impact /commercial potential of this Small Business Innovation Research (SBIR) Phase I project addresses the lack of instant, remote medical tests for telehealth. This project could develop an accurate machine learning-based predictive model for strep throat. The business model delivers an artificial intelligence (AI)-based clinical decision support system as a Software as a Service su ...

The broader impact of this Small Business Innovation Research (SBIR) Phase I project will be to develop methods to facilitate the efficient, reproducible insertion of large DNA segments into stable locations on bacterial vectors, viral and non-viral shuttle vectors, and the chromosomes of prokaryotic and eukaryotic host cells comprising novel target sequences plus helper and donor vectors that cou ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to improve the diagnosis of residual cancer cells, after treatment of cancer patients. The test will be conducted early and accurately using a simple blood draw. Twenty percent of cancer patients will experience cancer recurrence. Unfortunately, cancer recurrence is not diagnosed until year ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project will result from the development of a high-speed, low-power solver based on standard semiconductor technologies that can directly solve combinatorial optimization problem (COP) problems. COP problems have broad applicability across manufacturing optimization, semiconductor wire routing, logist ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is the creation of the first all-in-one automated syphilis test available at the point-of-care. The number of syphilis cases in the United States have doubled in the past 5 years with a five-fold increase in congenital syphilis passed from a pregnant mother to the fetus. Annual infections now ...