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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Soy-Based Structural Insulated Panels for Energy Efficient Housing

    SBC: IBIOCAT, INCORPORATED            Topic: 88

    The production of bioethanol is performed under non-sterile conditions and as a result is subjectto contamination.The industry typically treats the contamination with harsh chemicals and/orantibiotics with residues making their way into the byproducts including animal feed. Estimatesput the losses in production at 2 to 4% which translates at the lower end to an annual industry- wide loss of 316 mi ...

    SBIR Phase I 2019 Department of Agriculture
  2. Using Renewable Energy to Make Tilapia Production Financially Viable for Small Farms

    SBC: Arizona Green (Division of TeachSharp LLC)            Topic: 812

    Using Renewable Energy to Make Tilapia Production Financially Viable for Small FarmsInvestigator: Fox W.S. Institution: Arizona Green (Div. of Teach Sharp LLC) Elfrida AZMaking production of tilapia (and other warm-water fish) financially viable and sustainable on asmall-farm scale depends on several factors. The number-one constraint is the need to maintaino o tropical water temperatures (70 to 1 ...

    SBIR Phase I 2019 Department of Agriculture
  3. Development of Disease Resistant Pennycress as a Novel Oilseed Crop

    SBC: ARVEGENIX LLC            Topic: 82

    Field pennycress (Thlaspi arvense L.) a plant in the mustard family is emerging as a premierwinter cover crop for biofuel and edible oil production for the Midwestern agricultural rotationsystem because of its ease of genetic manipulation high oil content winter hardiness and itsability minimize soil erosion and leeching of nitrogen into waterways. Since it is grown off- season between corn and so ...

    SBIR Phase I 2019 Department of Agriculture
  4. Discovery of T-type Calcium Channel Antagonists from Multicomponent Reactions and Their Application in Paclitaxel-induced Peripheral Neuropathy

    SBC: Regulonix            Topic: 101

    Summary Abstract Chemotherapy induced peripheral neuropathyCIPNis detected inof cancer patients during all phases of cancerSensory symptoms in the hands and or feettypically in astocking glovepatternare commonand manifested as painnumbnessand or tinglingCIPN can result in chemotherapy dose reduction or discontinuationand can also have long term effects on the quality of lifeThe course of CIPN can ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Object Oriented Data Analysis for Untargeted Metabolomics

    SBC: WILLIAM D SHANNON CONSULTING LLC            Topic: 400

    PROJECT SUMMARY ABSTRACT In this Phase I SBIR applicationwe propose to develop and optimize functional Object Oriented Data AnalysisfOODAmethods and create a cloud based SaaS platform to analyze untargeted metabolomics dataUntargeted metabolomics quantifies the amount of known and unknown metabolites in samples with the purpose of finding known and unknown metabolites that correlate with subgroups ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Noninvasive Functional Cortical Mapping with Innovative tEEG

    SBC: CREmedical Corp            Topic: 106

    PROJECT SUMMARY Resective neurosurgery is essential for treating a range of neurologic conditions such as epilepsy and brain tumorsFor some patientswhose lesion is close to cortical language areaspostoperative expressive or receptive language deficit is a major and feared postoperative complicationMuch effort is devoted to identifying the cortical language regionsand relating such localization to ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Developing a Nutraceutical Product against Ototoxicity

    SBC: GATEWAY BIOTECHNOLOGY, INC.            Topic: NIDCD

    PROJECT SUMMARYDespite recent advances in cancer therapiesplatinum based drugs are still widely used for the treatment of solid tumorsA primary example is cisplatinwhich is frequently used to treat lungbladdertesticularand cervical cancersHoweverlimitations of this therapy include the development of drug resistance in cancer cells as well as severe side effectssuch as nephrotoxicity and neurotoxic ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Rapid high-resolution typing of Human Leukocyte Antigen genes by nanopore sequencing for transplantation

    SBC: NewVentureIQ, LLC            Topic: NIAID

    ABSTRACT Human leukocyte antigenHLAtyping is an essential laboratory test to evaluate the donor recipient compatibility before life saving transplantationsInaloneHLA typing of donors and recipients guided overorgan and stem cell transplantations in the United StatesExisting high resolution HLA typing methods require a turnaround time of days to weeksThere has been an unmet clinical need for a rapi ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Automated objective outcome measures for clinical use in dysarthria

    SBC: Aural Analytics, Inc.            Topic: NIDCD

    AbstractSummary The inability to engage in spoken communication is among the most debilitating of all human conditionsIn the field of communication disordersa speech language pathologist sSLP sperceptual evaluation of the quality of speech production is the gold standard for assessment and for documenting treatment progressHoweverdecades of research has confirmed that auditory perceptual judgments ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Glioblastoma multiforme therapy via telomerase reverse transcriptase (hTERT) down-regulation. Molecular chaperones redirect quadruplex folding to reverse the effect of hTERT gene promoter mutations.

    SBC: Reglagene, LLC            Topic: 106

    Project Summary Overexpression of hTERT is a hallmark of cancer and is associated with oncogenesistumor maintenanceand resistance to conventional chemotherapyElongated telomeres at the ends of chromosomes are a hallmark for cancer in the early stage of tumorigenesis and are associated with genetic instabilityAs a consequencesuppressed telomerase in normal cells is highly activated to immortalize t ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health

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