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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. AAAPT Technology for Improving Chemotherapy

    SBC: SCI-ENGI-MEDCO SOLUTIONS, INC            Topic: NCI

    DESCRIPTION provided by applicant Dysregulation of apoptosis pathways and loss of Human Beta Defensin hBD are the common tactics adapted by cancer cells to circumvent the effects of chemotherapy Consequently high dose of chemotherapy is required to obtain a clinically relevant therapeutic index which in turn compromises safety and develops resistance to therapy The problem is acute p ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A badge-like exposure device for occupational safety and epidemiological study

    SBC: TF HEALTH CORPORATION            Topic: 113

    Abstract Chemical exposure poses a threat to the safety and health of each of usespecially those who work in certain industriessuch as petroleum extraction and refinery facilitiesmining industryand fertilizer factoriesVarious sensing technologies have been developed over the past decades to address the needbut a low cost and accurate personal exposure device that can track multiple chemical pollut ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Abscription?-Based CpG Methylation Assays for Early Cancer Detection

    SBC: Ribomed Biotechnologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): This application is focused on the development of a simple and sensitive technology for the detection of CpG methylation in CpG islands of human cancer cells. CpG islands are short genomic segments in the promoter regio ns of most human genes that are enriched in the dinucleotide CpG. CpG islands are unmethylated in normal tissues but become progressively more ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  4. A capsule-based bioconjugate vaccine to prevent Klebsiella pneumoniae infections

    SBC: VaxNewMO            Topic: NIAID

    PROJECT SUMMARY Klebsiella pneumoniae is an encapsulated human pathogen capable of causing a myriad of human infections. Recently, K. pneumoniae has also emerged as one the most common causes of secondary bacterial pneumonia in COVID-19 patients. Over the last 40 years, K. pneumoniae has evolved into two distinct pathotypes, known as classical K. pneumoniae (cKp) and hypervirulent K. pneumoniae (h ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Accelerated absorption of insulin via a subcutaneously implanted, vascularized micro-chamber

    SBC: PROCYON TECHNOLOGIES LLC            Topic: 200

    Project Summary In Type I diabetic (T1D) patients, insulin is injected into the subcutaneous (SC) tissue, by needle or a pump and SC cannula. A bolus of insulin SC reaches its peak in about one hour or more. This slow absorption is in dramatic contrast to the secretion of insulin into the blood by the normal human pancreas, a process measured in seconds. Consequently, patients with T1D often strug ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. A COMPREHENSIVE OUTCOME SCALE FOR OUTPATIENT PSYCHIATRY

    SBC: PSYCH PRODUCTS PRESS            Topic: N/A

    DESCRIPTION (provided by applicant): The proposed project is related to NIMH research topic Assessment of Emotional and Psychological States. The goal is to develop a multidimensional, modular, self-report questionnaire that evaluates the course and outcome of psychiatric treatment. The Multidimensional Assessment of Symptoms and Psychosocial Functioning (MASP) is designed to assess symptom severi ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  7. A cost-effective robotic platform for on-demand production of flexibly dosed medications in a chewable gummy dosage form

    SBC: Vitae Industries, Inc.            Topic: NICHD

    PROJECT SUMMARYThis project s goal is to develop an innovative cost effective robotic platform for fast on demand pharmacy production of pediatric drugs as individually tailored palatable gummy dosage formsMedication adherence is notoriously low among children due to difficulty swallowing pills and rejection of bad tasting medicationsAlthough some common pediatric drugs have flavored liquid formsp ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Acoustic Bandgap Materials and Devices

    SBC: LASER FARE ADVANCED TECHNOLOGY GROUP            Topic: N/A

    N/A

    SBIR Phase I 1999 Department of DefenseDefense Advanced Research Projects Agency
  9. Acoustic Band Gap Materials and Devices

    SBC: LASER FARE ADVANCED TECHNOLOGY GROUP            Topic: N/A

    Laser Fare, working with Triton Systems, the Naval Undersea Weapons Center, and the Electric Boat Division of General Dynamics, recently completed the DARPA

    SBIR Phase I 2001 Department of DefenseDefense Advanced Research Projects Agency
  10. Acoustoelectric Echocardiography for Improving Prognosis and Guiding Treatment Decisions for Advanced Arrhythmias

    SBC: ElectroSonix LC            Topic: NHLBI

    ABSTRACT Atrial Fibrillation (AF) is characterized by a disorganized activation of the atrium leading to impaired cardiac function and more serious complications like embolic stroke, worsening heart failure, and increased mortality. AE affects 9% of the U.S. population (2% younger than 65) and contributes to 750,000 hospitalizations and 130,000 deaths per year. There is a clear unmet clinical need ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
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