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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Discovery of T-type Calcium Channel Antagonists from Multicomponent Reactions and Their Application in Paclitaxel-induced Peripheral Neuropathy
SBC: Regulonix Topic: 101Summary Abstract Chemotherapy induced peripheral neuropathyCIPNis detected inof cancer patients during all phases of cancerSensory symptoms in the hands and or feettypically in astocking glovepatternare commonand manifested as painnumbnessand or tinglingCIPN can result in chemotherapy dose reduction or discontinuationand can also have long term effects on the quality of lifeThe course of CIPN can ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Screening Device for Autism Spectrum Disorders using High Stimulation Rate ABR with Continuous Loop Averaging Deconvolution
SBC: INTELLIGENT HEARING SYSTEMS CORP Topic: NIDCDThe purpose of this proposal is to develop an automated Auditory Brainstem ResponseABRbased neurological screening device and software module that will enhance the early detection of autism and other neurological conditionsAutism Spectrum DisordersASDhave an incidence rate ofBased onmillion births in the United States innew cases of ASD will be diagnosed from that birth cohort aloneThe practice of ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Object Oriented Data Analysis for Untargeted Metabolomics
SBC: WILLIAM D SHANNON CONSULTING LLC Topic: 400PROJECT SUMMARY ABSTRACT In this Phase I SBIR applicationwe propose to develop and optimize functional Object Oriented Data AnalysisfOODAmethods and create a cloud based SaaS platform to analyze untargeted metabolomics dataUntargeted metabolomics quantifies the amount of known and unknown metabolites in samples with the purpose of finding known and unknown metabolites that correlate with subgroups ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
AHTP-comet: development of an automated, high throughput comet assay system
SBC: ENGINEERING RESOURCES GROUP INC Topic: NIEHSPROJECT SUMMARY Genomic instabilityinduced by DNA damageand partly mitigated by DNA repair and antioxidantsplays a critical role in the pathogenesis of many major human diseasessuch as neurodegenerationcancer and cardiovascular diseasetogether with agingThere is a critical need for automated assays that can perform these assessmentsand bring them into greater routine usewhich will help advance our ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Leadless Pacemaker Betavoltaic Power Source
SBC: CITY LABS, INC. Topic: NHLBILeadless cardiac pacemakersLCPsrepresent a revolutionary leap forward in cardiac pacing technology via its circumvention of transvenous leadsCurrent LCP lithium CFX batteries arecc resulting in an overallcc LCP deviceThis Phase I effort will demonstrate the feasibility of acc betavoltaic battery for LCPs with ayear lifetimex lifetime of current LCP batteriesenabling LCPs with a volumetric size ofc ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Noninvasive Functional Cortical Mapping with Innovative tEEG
SBC: CREMEDICAL CORP Topic: 106PROJECT SUMMARY Resective neurosurgery is essential for treating a range of neurologic conditions such as epilepsy and brain tumorsFor some patientswhose lesion is close to cortical language areaspostoperative expressive or receptive language deficit is a major and feared postoperative complicationMuch effort is devoted to identifying the cortical language regionsand relating such localization to ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Developing a Nutraceutical Product against Ototoxicity
SBC: GATEWAY BIOTECHNOLOGY, INC. Topic: NIDCDPROJECT SUMMARYDespite recent advances in cancer therapiesplatinum based drugs are still widely used for the treatment of solid tumorsA primary example is cisplatinwhich is frequently used to treat lungbladdertesticularand cervical cancersHoweverlimitations of this therapy include the development of drug resistance in cancer cells as well as severe side effectssuch as nephrotoxicity and neurotoxic ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Rapid high-resolution typing of Human Leukocyte Antigen genes by nanopore sequencing for transplantation
SBC: NEWVENTUREIQ LLC Topic: NIAIDABSTRACT Human leukocyte antigenHLAtyping is an essential laboratory test to evaluate the donor recipient compatibility before life saving transplantationsInaloneHLA typing of donors and recipients guided overorgan and stem cell transplantations in the United StatesExisting high resolution HLA typing methods require a turnaround time of days to weeksThere has been an unmet clinical need for a rapi ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Automated objective outcome measures for clinical use in dysarthria
SBC: Aural Analytics LLC Topic: NIDCDAbstractSummary The inability to engage in spoken communication is among the most debilitating of all human conditionsIn the field of communication disordersa speech language pathologist sSLP sperceptual evaluation of the quality of speech production is the gold standard for assessment and for documenting treatment progressHoweverdecades of research has confirmed that auditory perceptual judgments ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Glioblastoma multiforme therapy via telomerase reverse transcriptase (hTERT) down-regulation. Molecular chaperones redirect quadruplex folding to reverse the effect of hTERT gene promoter mutations.
SBC: Reglagene, LLC Topic: 106Project Summary Overexpression of hTERT is a hallmark of cancer and is associated with oncogenesistumor maintenanceand resistance to conventional chemotherapyElongated telomeres at the ends of chromosomes are a hallmark for cancer in the early stage of tumorigenesis and are associated with genetic instabilityAs a consequencesuppressed telomerase in normal cells is highly activated to immortalize t ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health