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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Natural Rubber Production

    SBC: American Sustainable Rubber Company, LLC            Topic: ST18C001

    Rubber is pervasive in our economy, with over 50,000 products requiring natural rubber (NR), including military grade tires. Yet significant global shortfalls are projected. Rubber dandelion (Taraxacum kok-saghyz) produces natural rubber (cis-1,4, -polyisoprene) in root latex vessels (laticifers) almost identical to rubber from the tropical rubber tree (Hevea brasiliensis). Problem: Cost-effective ...

    STTR Phase I 2019 Department of DefenseDefense Advanced Research Projects Agency
  2. TOPIC 363: myCare2- Supporting Caregivers and Caregiving

    SBC: BRIGHTOUTCOME INC.            Topic: NCI

    The myCare2 solution will be marketed to cancer care organizations and include three separate portals for cancer caregivers, patients and providers. The system will be mobile-enabled and support standards-based EHR integration. Primary myCare2 features include symptom assessment, communication with the care team, care plan dissemination, tailored education content for caregiving and for caregiver ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Developing specific rapid and cost effective immunoassays for Zika detection

    SBC: MEDIOMICS, LLC            Topic: R

    This proposal aims to develop highly specific rapid and cost effective immunoassays to detect Zika virus ZIKV infection ZIKV is a single stranded RNA virus in the Flaviviridae family that is transmitted to humans through infected mosquitos blood transfusions and sexual contact As of June around Zika Virus disease cases have been estimated in Brazil alone Recently ZIKV has be ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. A Metabologenomics Platform for Large Scale High Throughput Natural Product Discovery

    SBC: Microbial Pharmaceuticals, Inc.            Topic: NCCIH

    ABSTRACT The estimates of natural product producing gene clusters within the genomes of microorganisms are far greater than the number of known natural products indicating that there is a wealth of untapped molecules within these organisms that offer huge potential as leads for new medicines Unfortunately the prevailing paradigms for natural product discovery are ill suited for accessing this ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Targeting the alternative pathway to treat age related macular degeneration

    SBC: Serion, Inc            Topic: N

    Targeting the alternative pathway of complement to treat age related macular degeneration Abstract Age related macular degeneration AMD is the leading cause of vision loss in the developed world in people over and is a priority research area for the National Eye Institute It is a progressive degenerative disease that causes loss of the central vision due to destruction of the part of the re ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. The Preemie Pacer An Innovative Bottle to Promote Safe and Efficient Oral Feeding in Preterm Infants

    SBC: Preemie-Pacer, LLC            Topic: NICHD

    PROJECT SUMMARY ABSTRACT There are infants born preterm each year in the United States alone Preterm infants often necessitate care in the neonatal intensive care unit One of the final milestones to be achieved in order to be discharged from the neonatal intensive care unit is oral feeding Oral feeding can be a challenge for infants born preterm as they do not have the maturity that all ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. A rapid and portable test for home monitoring of phenylalanine levels by patients with phenylketonuria using a blood glucose meter

    SBC: GlucoSentient, Inc            Topic: NICHD

    Project Summary Abstract Phenylketonuria PKU is a serious inborn metabolic disorder affecting out of every children born in the U S annually Characteristic effect of PKU is the impaired capability of the body to convert the amino acid phenylalanine Phe to tyrosine and as a result Phe level is elevated in the blood stream While Phe is required for normal growth and brain developm ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Disaggregation of Toxic Protein Oligomers in Brain with Electromagnetic Treatment

    SBC: NeuroEM Therapeutics, Inc.            Topic: 104

    ABSTRACT Formation of misfolded protein oligomers in neurons is an early and causative event in a variety of neurodegenerative diseases such as Alzheimer s Disease amyloid and tau oligomers Fronto temporal lobe dementia tau oligomers and Parkinson s Disease synuclein oligomers These toxic oligomers share a common aggregation mechanism that involves formation of hydrogen bonds betwee ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Application of PPODA QT for embolization of aneurysms

    SBC: Aneuvas Technologies, Inc.            Topic: 101

    A cerebral aneurysm is an abnormal enlargement or pouch that forms from a weakened vessel segment in the brain Often going unnoticed and untreated an aneurysm can cause a sudden and catastrophic hemorrhage or stroke Approximately of patients die from an aneurysm rupture even before receiving medical attention and of patients die despite medical treatment Patients that survive typical ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Towards a New Generation of Glycoengineered Pneumococcal Bioconjugate Vaccines

    SBC: VaxNewMO            Topic: NIAID

    PROJECT SUMMARY Pneumococcal pneumonia remains the leading cause of bacterial pneumonia in both children under years of age and adults over years of age The standard preventative therapy is the conjugate vaccine Prevnar which consists of an immunogenic carrier protein covalently attached to one of thirteen pneumococcal capsular polysaccharides Although Prevnar has significantly red ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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