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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Open System Manufacturing of Large Sensing/Weapons Platforms
SBC: Applied Radar, Inc. Topic: SB102005In order to maintain our nation’s technological superiority on air, sea and land, we must respond quicker to emerging threats and reduce the cost of major sensing platforms. Every DoD platform developed nowadays contains at least one sensor, whether it be RF, EO/IR, or acoustic. In fact, in a lot of recent developments, the platform is built around the sensor and exists only to support the senso ...
SBIR Phase I 2010 Department of DefenseDefense Advanced Research Projects Agency -
Combination Therapy of Aspirin and Apyrase for Stroke
SBC: APT THERAPEUTICS, INC. Topic: NINDSDESCRIPTION (provided by applicant): Human apyrase represents a highly promising therapy for acute ischemic stroke which is a leading cause of death and disability with almost no effective therapy for most patients. This enzyme strongly inhibits platelet activation and aggregation with modest bleeding risk. We will validate hypothesis that in thromboembolic model of stroke in rats, combination tre ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Rapid, Low-Cost Cell-Sorting System for Diagnosis of Candidemia
SBC: SOFTRAY, INC. Topic: NHLBIDESCRIPTION (provided by applicant): This SBIR Phase I project will prove the concept for a low-cost, point-of-care system for real-time diagnosis of candidemia (fungal infection of blood). Hospital-acquired infections occur in ~10% of the patients in critical care facilities in the US, and Candida species are currently the 4th leading cause of blood stream infection. They are associated with attr ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Facile Detection of Soil-Transmitted Helminth Infections
SBC: Divergence, Inc. Topic: NIAIDDESCRIPTION (provided by applicant): The goal of this project is to develop a rapid and accurate immunodiagnostic test for detection of soil- transmitted helminths (STHs) that can be used without laboratory infrastructure. Human STH infections from whipworm (Trichuris), roundworm (Ascaris), and hookworms (Necator and Ancylostoma) create a substantial burden to worldwide public h ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Whole-brain fluorescence and brightfield imaging at single-cell level
SBC: DMetrix, Inc Topic: NIADESCRIPTION (provided by applicant): The goal of this project is to develop an open and flexible imaging platform capable of rapid, 0.5- 5 m pixel resolution image capture of large-area histology sections (up to 125 mm by 175 mm), in brightfield and by epi-fluorescence optical sectioning. The project involves state-of-the- art instrumentation development coupled with application programming inter ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Direct RT-PCR detection of RNA pathogens and mRNA expression in crude samples
SBC: DNA POLYMERASE TECHNOLOGY, INC. Topic: NIGMSDESCRIPTION (provided by applicant): We propose to develop a highly simplified and improved method of detecting RNA for use in clinical tests and for scientific research by enabling the RT-PCR amplification of nucleic acids directly in whole blood, serum, plasma, and cell lysates. We propose a dual approach. We will work with two of our blood inhibition Taq mutants combined with a viral reverse tr ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Nuclease Probe Mediated Sequencing
SBC: HIGH THROUGHPUT GENOMICS, INC. Topic: NHGRIDESCRIPTION (provided by applicant): Sequencing is very powerful for identifying differences in genomic DNA that may regulate cell function and diseases, pre-dispose persons to certain diseases, or warn of adverse drug metabolism. It provides a basis for identifying differences in gene expression, though such applications have been limited and are problematic because each expressed gene can vary f ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Not Available
SBC: HIGH THROUGHPUT GENOMICS, INC. Topic: NIEHSThis Phase I proposal will develop and validate assays to measure the metabolism of compounds and their affect on liver cells using a multiplexed gene expression assay platform, the quantitative Nuclease Protection Assay (qNAP¿) that can measure the expression of up to 100 mRNA and miRNA and is a simple, robust and highly precise assay that provides high sample throughput. Two cell systems wil ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Not Available
SBC: HIGH THROUGHPUT GENOMICS, INC. Topic: NCIA molecular test using FFPE tissue from patients to distinguish basal-like breast cancer from other subtypes will be developed and confirmed. The test will be based on a commercial platform, the lysis-on ly quantitative Nuclease Protection Assay (qNPA 1M). Current gene expression signatures described for breast cancer, in particular those for distinguishing basal-like breast cancer from other subt ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Screening Test for HPV+ Head and Neck Cancer
SBC: HIGH THROUGHPUT GENOMICS, INC. Topic: NIAIDDESCRIPTION (provided by applicant): There is currently no good way to screen for early stages of head and neck cancers caused by high risk types of human papillomavirus. The objective of this proposal is to develop a screening assay for dental patients to detect HPV+ head and neck cancer ( HNC ) pre-symptomatically, based on the use of viral and host gene biomarkers. The overall hypothesis of thi ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health